Podcast 668: Opioid-Induced Hyperalgesia

Podcast 668: Opioid-Induced Hyperalgesia

Contributor: Donald Stader, MD

Educational Pearls:

  • Opioids target kappa and NMDA receptors that can lead to central nervous system sensitization and therefore increased pain
  • For patients with opioid-induced hyperalgesia (OIH), oral ketamine (25-50 mg) can be used to treat their pain as it targets the NMDA receptor
  • Other treatments is IV magnesium, NSAIDs, tylenol, and clonidine
  • Buprenorphine and methadone are options for chronic pain management in the setting of OIH

References

Lee M, Silverman SM, Hansen H, Patel VB, Manchikanti L. A comprehensive review of opioid-induced hyperalgesia. Pain Physician. 2011;14(2):145-161.

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD

The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at www.emergencymedicalminute.com/cme-courses/ and create an account.

Donate to EMM today!



Avsnitt(1146)

UNTAMED PART 2: Surviving a Medical Emergency in the Outdoors

UNTAMED PART 2: Surviving a Medical Emergency in the Outdoors

11 Mars 201917min

UNTAMED PART 1: The Physiology of Experiencing Nature

UNTAMED PART 1: The Physiology of Experiencing Nature

11 Mars 201917min

Podcast #445: Hunting for the endotracheal tube

Podcast #445: Hunting for the endotracheal tube

Author: Michael Hunt, MD Educational Pearls: Bedside transtracheal ultrasound to confirm proper endotracheal intubation is simple and effective Review of 17 studies showed transtracheal ultrasound wa...

8 Mars 20192min

Podcast #444: Dyspnea in the intubated patient

Podcast #444: Dyspnea in the intubated patient

Author: Aaron Lessen, MD Educational Pearls: Dyspnea can occur in up to 50% of intubated patients Dyspnea is associated with prolonged mechanical intubation Often goes undiagnosed as these patients h...

6 Mars 20192min

Podcast #443: Measles - a timely revisit

Podcast #443: Measles - a timely revisit

Author: Sue Chilton, MD Educational Pearls: Measles is highly contagious Typically patients just look sick Remember 4 & 4, 14, and 4-C's: Contagious 4 days before and after onset of rash 14 days fo...

4 Mars 20193min

Podcast #442: When a severe man cold isn't

Podcast #442: When a severe man cold isn't

Author: Jared Scott, MD Educational Pearls: CXR is 40-90% sensitive for detecting pneumonia when compared to CT Patients with a high degree of suspicion for pneumonia may still warrant treatment de...

2 Mars 20194min

Podcast #441: Is Heparin Worthless for ACS?

Podcast #441: Is Heparin Worthless for ACS?

Author: Don Stader, MD Educational Pearls: Recent study demonstrated patients with non-STEMI treated with heparin had no difference in survival, but had an increased risk of major bleeding Heparin ...

27 Feb 20193min

Podcast # 440 : Carbon Monoxide Poisoning

Podcast # 440 : Carbon Monoxide Poisoning

Author: Katie Sprinkle, MD Educational Pearl: Carbon monoxide (CO) is the leading cause of death from poison world-wide CO forms from the combustion of any carbon based product Patients often prese...

25 Feb 20194min

Populärt inom Vetenskap

dumma-manniskor
svd-nyhetsartiklar
p3-dystopia
allt-du-velat-veta
kapitalet-en-podd-om-ekonomi
det-morka-psyket
rss-ufo-bortom-rimligt-tvivel
rss-vetenskapsradion
pojkmottagningen
sexet
rss-vetenskapsradion-2
dumforklarat
rss-broccolipodden-en-podcast-som-inte-handlar-om-broccoli
medicinvetarna
halsorevolutionen
bildningspodden
rss-experimentet
rss-spraket
hacka-livet
vetenskapsradion