Podcast 678: ECMO for Refractory VFib

Podcast 678: ECMO for Refractory VFib

Contributor: Aaron Lessen, MD

Educational Pearls:

  • Refractory ventricular fibrillation, defined as 3 defibrillation shocks without resolution, was studied via RCT looking to compare ECMO with cardiac cath vs. typical resuscitation
  • After 30 patients (15 each arm), the trial was stopped because such a significant benefit seen in the ECMO arm
  • 6 patients survived and 3 had good neurological outcomes at 6 months with ECMO
  • This is compared to 1 patient surviving initially and none surviving at 6 months in the typical resuscitation arm

References

Yannopoulos D, Bartos J, Raveendran G, et al. Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial. Lancet. 2020;396(10265):1807-1816. doi:10.1016/S0140-6736(20)32338-2

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD

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Podcast 689: Peri-Intubation Hypotension

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Podcast 688: tPA Before Thrombectomy

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Contributor: Aaron Lessen, MD Educational Pearls: DEVT Trial, a recent non-inferiority study, looked at giving tPA prior to endovascular thrombectomy and was stopped early because there was no benefi...

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Podcast 687: STI Complications

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Contributor: Jared Scott, MD Educational Pearls: PID (pelvic inflammatory disease) occurs when the infection ascends into the uterus Tubo-ovarian abscess occurs when the infection ascends to the fall...

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