Emergency Medical Minute15 Nov 2021

Podcast 729: Molnupiravir for COVID

Contributor: Jared Scott, MD

Educational Pearls:

A press release from Merck introduced Molnupiravir for treatment of mild to moderate COVID-19
The yet to be published study is a randomized control trial at around 100 different sites
Reported outcomes were hospitalization and mortality from COVID and mortality from COVID
Molnupiravir was found to be twice as effective as placebo looking at these two endpoints (7% vs. 14%)
5 day course of the drug taken twice per day costs $700, but cost-saved from using this drug was $32,000 per patient

References

https://www.merck.com/news/merck-and-ridgebacks-investigational-oral-antiviral-molnupiravir-reduced-the-risk-of-hospitalization-or-death-by-approximately-50-percent-compared-to-placebo-for-patients-with-mild-or-moderat/

https://www.merck.com/news/merck-and-ridgebacks-molnupiravir-an-oral-covid-19-antiviral-medicine-receives-first-authorization-in-the-world/

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD

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