Emergency Medical Minute16 Maj 2022

Podcast 781: Foxglove, Dropsy, and Salvador Dali

Contributor: Chris Holmes, MD

Educational Pearls:

Foxglove plant contains the cardiac glycoside digoxin
Foxglove leaf potions were once used to treat Dropsy; a historic term for symptoms of heart failure
Digoxin, previously used for treating heart failure, works by increases heart contraction strength and slows heart rate
Of note, the EKG of patient on digitalis may have a 'Dali Mustache' appearance
Digoxin toxicity can lead to a variety of dysrhythmias as well as neurological, GI, and metabolic effects
Treatment of digoxin toxicity is digoxin-immune fab, which is an antibody that binds digoxin

References

David MNV, Shetty M. Digoxin. [Updated 2021 Dec 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556025/

Cummings ED, Swoboda HD. Digoxin Toxicity. [Updated 2021 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470568/?report=classic

Summarized by Kirsten Hughes, MS4 | Edited by John Spartz MS4 & Erik Verzemnieks, MD

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