Podcast 863: Treatments for Alcohol Use Disorder

Podcast 863: Treatments for Alcohol Use Disorder

Contributor: Aaron Lessen MD

Educational Pearls:

  • Patients with alcohol use disorder are frequently discharged from the ED without further resources

  • Pharmacological treatments to reduce cravings in AUD exist

  • Naltrexone

    • Effective at reducing alcohol cravings and heavy drinking

  • Gabapentin

    • Reduces the percentage of heavy drinking days in AUD

  • Patients being discharged from the ED should be asked if they feel their alcohol use is a problem, which can further direct appropriate pharmacological interventions

References

1. Kranzler M.D. HR, Feinn Ph.D. R, Morris B.A. P, Hartwell Ph.D. EE. A Meta-analysis of the Efficacy of Gabapentin for Treating Alcohol Use Disorder Henry. Addiction. 2019;114(9):1547-1555. doi:10.1111/add.14655

2. Maisel NC, Blodgett JC, Wilbourne PL, Humphreys K, Finney JW. Meta-analysis of naltrexone and acamprosate for treating alcohol use disorders: When are these medications most helpful? Addiction. 2013;108(2):275-293. doi:10.1111/j.1360-0443.2012.04054.x

3. Mariani JJ, Pavlicova M, Basaraba C, et al. Pilot randomized placebo-controlled clinical trial of high-dose gabapentin for alcohol use disorder. Alcohol Clin Exp Res. 2021;45(8):1639-1652. doi:10.1111/acer.14648

Summarized & Edited by Jorge Chalit, OMSII

Avsnitt(1149)

Podcast 636: May-Thurner Syndrome

Podcast 636: May-Thurner Syndrome

Contributor: Sam Killian, MD Educational Pearls: iliac vein compression syndrome is also called May-Thurner Syndrome The left leg more frequently develops deep venous thrombosis (DVT) in part because...

1 Feb 20213min

Pharmacy Phriday #8: Atropine with Ketamine for Conscious Sedation of Pediatrics

Pharmacy Phriday #8: Atropine with Ketamine for Conscious Sedation of Pediatrics

Educational Pearls: Atropine has been shown to reduce hypersalivation as well as nausea and vomiting induced by ketamine sedation. Atropine can increase the occurrence of a transient rash, as well a...

29 Jan 20213min

Podcast 635: Wide Complex Tachycardias

Podcast 635: Wide Complex Tachycardias

Contributor: Peter Bakes, MD Educational Pearls: Two main differentials for wide complex tachycardia (WCT) include ventricular tachycardia (most common) and supraventricular tachycardia with aberranc...

26 Jan 20215min

Podcast 634: D10 for Hypoglycemia

Podcast 634: D10 for Hypoglycemia

Contributor: Dylan Luyten, MD Educational Pearls: D10 may be a better alternative to D50 in correcting hypoglycemia Risks of D50: Can cause extravasation injury Risk of rebound hypoglycemia D10 ...

25 Jan 20214min

Podcast 633: Pathologic Femur Fractures

Podcast 633: Pathologic Femur Fractures

Contributor: Jared Scott, MD Educational Pearls: Pathologic bone fractures occur due to weakened bones from chronic disease and with less force when compared to non-pathologic fractures Can be due to...

19 Jan 20215min

Podcast 632: Neonatal Jaundice

Podcast 632: Neonatal Jaundice

Contributor: Jared Scott, MD Educational Pearls: Bilirubin is natural breakdown product of red blood cells but can be neurotoxic if levels become too high Fetal red blood cells are fragile and break ...

18 Jan 20216min

Pharmacy Phriday #7: Bactrim Adverse Events

Pharmacy Phriday #7: Bactrim Adverse Events

Contributor: Cheyenne Bean, PharmD Educational Pearls: Bactrim (TMP-SMX) is a sulfa antibiotic used for a number of infections but can have untoward effects. Hypoglycemia can be induced by the sulfa ...

15 Jan 20214min

Podcast 631: UK COVID-19 Mutation

Podcast 631: UK COVID-19 Mutation

Contributor: Gretchen Hinson, MD Educational Pearls: Viruses mutate frequently and a new variant of COVID has been found in the United Kingdom. Mutations typically occur due to transcription errors d...

13 Jan 20215min

Populärt inom Vetenskap

svd-nyhetsartiklar
dumma-manniskor
p3-dystopia
allt-du-velat-veta
rss-vetenskapsradion-2
medicinvetarna
kapitalet-en-podd-om-ekonomi
rss-ufo-bortom-rimligt-tvivel-2
rss-vetenskapsradion
det-morka-psyket
bildningspodden
hacka-livet
halsorevolutionen
vetenskapsradion
rss-geopodden-2
sexet
rss-arkeologi-historia-podden-som-graver-i-vart-kulturlandskap
rss-experimentet
dumforklarat
matfrihet