Episode 903: Treating Precipitated Opioid Withdrawal

Episode 903: Treating Precipitated Opioid Withdrawal

Contributor: Aaron Lessen MD

Educational Pearls:

  • Opioid overdoses that are reversed with naloxone (Narcan), a mu-opioid antagonist, can precipitate acute withdrawal in some patients

  • Treatment of opioid use disorder with buprenorphine can also precipitate withdrawal

  • Opioid withdrawal symptoms include nausea, vomiting, diarrhea, and agitation

  • Buprenorphine works as a partial agonist at mu-opioid receptors, which may alleviate withdrawal symptoms

    • The preferred dose of buprenorphine is 16 mg

  • Treatment of buprenorphine-induced opioid withdrawal is additional buprenorphine

  • Adjunctive treatments may be used for other opioid withdrawal symptoms

    • Nausea with ondansetron

    • Diarrhea with loperamide

    • Agitation with hydroxyzine

References

1. Quattlebaum THN, Kiyokawa M, Murata KA. A case of buprenorphine-precipitated withdrawal managed with high-dose buprenorphine. Fam Pract. 2022;39(2):292-294. doi:10.1093/fampra/cmab073

2. Spadaro A, Long B, Koyfman A, Perrone J. Buprenorphine precipitated opioid withdrawal: Prevention and management in the ED setting. Am J Emerg Med. 2022;58:22-26. doi:10.1016/j.ajem.2022.05.013

Summarized by Jorge Chalit, OMSII | Edited by Meg Joyce & Jorge Chalit

Avsnitt(1145)

Podcast 581:  Alcohol Complications

Podcast 581: Alcohol Complications

\Contributor: Don Stader, MD Educational Pearls: Altered mental status/confusion are major symptoms associated with both alcohol use and withdrawal. Wernicke's encephalopathy is a triad of symptoms o...

27 Juli 20206min

On The Streets #6: Artificial Intelligence Detection for LVOs

On The Streets #6: Artificial Intelligence Detection for LVOs

Meet Michelle Whaley, Clinical Nurse Specialist and Stroke Program Coordinator at Sky Ridge Medical Center in Lone Tree, Colorado. Jordan and Michelle discuss advances in Artificial Intelligence techn...

22 Juli 202021min

Podcast 580:  Origin of PPE

Podcast 580: Origin of PPE

Contributor: Michael Hunt, MD Educational Pearls: PPE, or personal protective equipment, has become a major talking point since the emergence of the novel coronavirus (COVID 19). While ubiquitous now...

21 Juli 20204min

Podcast 579:  Yersinia Pestis

Podcast 579: Yersinia Pestis

Contributor: Don Stader, MD Educational Pearls: Yersinia Pestis is the bacteria that caused the black plague. It was first discovered to be the cause of the bubonic plague in 1800s in China during th...

20 Juli 20203min

Podcast 578: Brown-Sequard Syndrome

Podcast 578: Brown-Sequard Syndrome

Author: Eric Miller, MD Educational Pearls: Brown-Sequard Syndrome is a neurological deficit that results from hemisection of the spinal cord  This is usually from traumatic injury (blunt or penetrat...

14 Juli 20202min

Podcast 577:  Immunotherapies

Podcast 577: Immunotherapies

Contributor: Don Stader, MD Educational Pearls: Checkpoint inhibition normally helps our body detect abnormal cells and terminate it but cancerous cells often are able to avoid this countermeasure Mo...

13 Juli 20206min

UnfilterED #9: Dr. Steven Bradley

UnfilterED #9: Dr. Steven Bradley

Dr. Steven Bradley is an active duty U.S. Naval officer practicing as a Staff Anesthesiologist in Virginia where also resides on the Medical Ethics Committee for his hospital. He serves as the Anesthe...

8 Juli 202039min

Podcast 576: Status Epilepticus Drugs

Podcast 576: Status Epilepticus Drugs

Author: Charlene Gnisci Melton, PharmD Educational Pearls: Status Epilepticus is defined as continuous seizure activity for >5 minutes, or 2 or more seizures without full return to consciousness betw...

7 Juli 20205min

Populärt inom Vetenskap

p3-dystopia
dumma-manniskor
svd-nyhetsartiklar
allt-du-velat-veta
det-morka-psyket
kapitalet-en-podd-om-ekonomi
pojkmottagningen
sexet
rss-ufo-bortom-rimligt-tvivel
rss-vetenskapsradion-2
rss-vetenskapsradion
dumforklarat
halsorevolutionen
rss-broccolipodden-en-podcast-som-inte-handlar-om-broccoli
medicinvetarna
rss-experimentet
bildningspodden
vetenskapsradion
hacka-livet
intergalaktiskt