Economics Roundtable: Investors Eye Central Banks

Economics Roundtable: Investors Eye Central Banks

Morgan Stanley’s chief economists examine the varied responses of global central banks to noisy inflation data in their quarterly roundtable discussion.


----- Transcript -----

Seth Carpenter: Welcome to Thoughts on the Market. I'm Seth Carpenter, Morgan Stanley's global chief economist. We have a special two-part episode of the podcast where we'll cover Morgan Stanley's global economic outlook as we look into the third quarter of 2024.

It's Friday, June 21st at 10am in New York.

Jens Eisenschmidt: And 4pm in Frankfurt.

Chetan Ahya: And 10pm in Hong Kong.

Seth Carpenter: Alright, so a lot's happened since our last economics roundtable on this podcast back in March and since we published our mid-year outlook in May. My travels have taken me to many corners of the globe, including Tokyo, Sao Paulo, Sydney, Washington D. C., Chicago.

Two themes have dominated every one of my meetings. Inflation in central banks on the one hand, and then on the other hand, elections.

In the first part of this special episode, I wanted to discuss these key topics with the leaders of Morgan Stanley Economics in key regions. Ellen Zentner is our Chief US Economist, Jens Eisenschmidt is our Chief Europe Economist, and Chetan Ahya is our Chief Asia Economist.

Ellen, I'm going to start with you. You've also been traveling. You were in London recently, for example. In your conversations with folks, what are you explaining to people? Where do things stand now for the Fed and inflation in the US?

Ellen Zentner: Thanks, Seth. So, we told people that the inflation boost that we saw in the first quarter was really noise, not signal, and it would be temporary; and certainly, the past three months of data have supported that view. But the Fed got spooked by that re-acceleration in inflation, and it was quite volatile. And so, they did shift their dot plot from a median of three cuts to a median of just one cut this year. Now, we're not moved by the dot plot. And Chair Powell told everyone to take the projections with a grain of salt. And we still see three cuts starting in September.

Jens Eisenschmidt: If you don't mind me jumping in here, on this side of the Atlantic, inflation has also been noisy and the key driver behind repricing in rate expectations. The ECB delivered its cut in June as expected, but it didn't commit to much more than that. And we had, in fact, anticipated that cautious outcome simply because we have seen surprises to the upside in the April, and in particular in the May numbers. And here, again, the upside surprise was all in services inflation.

If you look at inflation and compare between the US experience and euro area experience, what stands out at that on both sides of the Atlantic, services inflation appears to be the sticky part. So, the upside surprises in May in particular probably have left the feeling in the governing council that the process -- by which they got more and more confidence in their ability to forecast inflation developments and hence put more weight on their forecast and on their medium-term projections – that confidence and that ability has suffered a slight setback. Which means there is more focus now for the next month on current inflation and how it basically compares to their forecast.

So, by implication, we think upside surprises or continued upside surprises relative to the ECB's path, which coincides in the short term with our path, will be a problem; will mean that the September rate cut is put into question.

For now, our baseline is a cut in September and another one in December. So, two more this year. And another four next year.

Seth Carpenter: Okay, I get it. So, from my perspective, then, listening to you, Jens, listening to Ellen, we're in similar areas; the timing of it a little bit different with the upside surprise to inflation, but downward trend in inflation in both places. ECB already cutting once. Fed set to start cutting in September, so it feels similar.

Chetan, the Bank of Japan is going in exactly the opposite direction. So, our view on the reflation in Japan, from my conversations with clients, is now becoming more or less consensus. Can you just walk us through where things stand? What do you expect coming out of Japan for the rest of this year?

Chetan Ahya: Thanks, Seth. So, Japan's reflation story is very much on track. We think a generational shift from low-flation to new equilibrium of sustainable moderate inflation is taking hold. And we see two key factors sustaining this story going forward. First is, we expect Japan's policymakers to continue to keep macro policies accommodative. And second, we think a virtuous cycle of higher prices and wages is underway.

The strong spring wage negotiation results this year will mean wage growth will rise to 3 percent by third quarter and crucially the pass through of wages to prices is now much stronger than in the past -- and will keep inflation sustainably higher at 1.5 to 2 per cent. This is why we expect BOJ to hike by 15 basis points in July and then again in January of next year by 25 basis points, bringing policy rates to 0.5 per cent.

We don't expect further rate hikes beyond that, as we don't see inflation overshooting the 2 percent target sustainably. We think Governor Ueda would want to keep monetary policy accommodative in order for reflation to become embedded. The main risk to our outlook is if inflation surprises to the downside. This could materialize if the wage to price pass through turns out to be weaker than our estimates.

Seth Carpenter: All of that was a great place to start. Inflation, central banking, like I said before, literally every single meeting I've had with clients has had a start there. Equity clients want to know if interest rates are coming down. Rates clients want to know where interest rates are going and what's going on with inflation.

But we can't forget about the overall economy: economic activity, economic growth. I will say, as a house, collectively for the whole globe, we've got a pretty benign outlook on growth, with global growth running about the same pace this year as last year. But that top level view masks some heterogeneity across the globe.

And Chetan I'm going to come right back to you, staying with topics in Asia. Because as far as I can remember, every conversation about global economic activity has to have China as part of it. China's been a key part of the global story. What's our current thinking there in China? What's going on this year and into next year?

Chetan Ahya: So, Seth, in China, cyclically improving exports trend has helped to stabilize growth, but the structural challenges are still persisting. The biggest structural challenge that China faces is deflation. The key source of deflationary pressure is the housing sector. While there is policy action being taken to address this issue, we are of the view that housing will still be a drag on aggregate demand. To contextualize, the inventory of new homes is around 20 million units, as compared to the sales of about 7 to 8 million units annually. Moreover, there is another 23 million units of existing home inventory.

So, we think it would take multiple years for this huge inventory overhang to

be digested to a more reasonable level. And as downturn in the property sector is resulting in downward pressures on aggregate demand, policy makers are supporting growth by boosting supply.

Consider the shifts in flow of credit. Over the past few years, new loans to property sector have declined by about $700 billion, but this has been more than offset by a rise of about $500 billion in new loans for industrial sector, i.e. manufacturing investment, and $200 billion loans for infrastructure. This supply -centric policy response has led to a buildup of excess capacities in a number of key manufacturing sectors, and that is keeping deflationary pressures alive for longer. Indeed, we continue to see the diversions of real GDP growth and normal GDP growth outcomes. While real GDP growth will stabilize at 4.8 per cent this year, normal GDP growth will still be somewhat subdued at 4.5 per cent.

Seth Carpenter: Thanks, Chetan. That's super helpful.

Jens, let's think about the euro area, where there had, been a lot of slower growth relative to the US. I will say, when I'm in Europe, I get that question, why is the US outperforming Europe? You know, I think, my read on it, and you should tell me if I'm right or not -- recent data suggests that things, in terms of growth at least have bottomed out in Europe and might be starting to look up. So, what are you thinking about the outlook for European growth for the rest of the year? Should we expect just a real bounce back in Europe or what's it going to look like?

Jens Eisenschmidt: Indeed, growth has bottomed. In fact, we are emerging from a period of stagnation last year; and as expected in our NTIA Outlook in November we had outlined the script -- that based on a recovery in consumption, which in turn is based on real wage gains. And fading restrictiveness of monetary policy, we would get a growth rebound this year. And the signs are there that we are exactly getting this, as expected.

So, we had a very strong first quarter, which actually led us to upgrade still our growth that we had before at 0.5 to 0.7. And we have the PMIs, the survey indicators indicating indeed that the growth rebound is set to continue. And we have also upgraded the growth outlook for 2025 from 1 to 1.2 per cent here on the back of stronger external demand assumptions. So, all in all, the picture looks pretty consistent with that rebound.

At the same time, one word of caution is that it won't get very fast. We will see growth very likely peaking below the levels that were previous peaks simply because potential growth is lower; we think is lower than it has been before the pandemic. So just as a measure, we think, for instance, that potential growth in Europe could be here lie between one, maybe one, 1 per cent, whereas before it would be rather 1.5 per cent.

Seth Carpenter: Okay, that makes a lot of sense. So, some acceleration, maybe not booming, maybe not catching the US, but getting a little bit of convergence. So, Ellen, bring it back to the US for us. What are you thinking about growth for the US? Are we going to slump and slow down and start to look like Europe? Are things going to take off from here?

Things have been pretty good. What do you think is going to happen for the rest of this year and into next year?

Ellen Zentner: Yes, I think for the year overall, you know, growth is still going to be solid in the US, but it has been slowing compared with last year. And if I put a ‘the big picture view’ around it, you've got a fiscal impulse, where it's fading, right? So, we had big fiscal stimulus around COVID, which continues to fade. You had big infrastructure packages around the CHIPS Act and the IRA, where the bulk of that spending has been absorbed. And so that fiscal impulse is fading. But you've still got the monetary policy drag, which continues to build.

Now, within that, the immigration story is a very big offset. What does it mean, you know, for the mid-year outlook? We had upgraded growth for this year and next quite meaningfully. And we completely changed how we were thinking about sort of the normal run rate of job growth that would keep the unemployment rate steady.

So, whereas just six months ago, we thought it was around 100,000 to 120,000 a month, now we think that we can grow the labor market at about 250,000 a month, without being inflationary. And so that allows for that bigger but not tighter economy, which has been a big theme of ours since the mid-year outlook.

And so, I'm throwing in the importance of immigration in here because I know you want to talk about elections later on. So, I want to flag that as not just a positive for the economy, but a risk to the outlook as well.

Now, finally, key upcoming data is going to inform our view for this year. So, I'm looking for: Do households slow their spending because labor income growth is slowing? Does inflation continue to come down? And do job gains hold up?

Seth Carpenter: Alright, thanks Ellen. That helps a lot, and it puts things into perspective. And you're right, I do want to move on to elections, but that will be for the second part of this special episode. Catch that in your podcast feeds on Monday.

For now, thank you for listening. And if you enjoy the podcast, please leave a review wherever you listen and share Thoughts On the Market with a friend or colleague today.


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A Bullish Case for Large Cap U.S. Equities

A Bullish Case for Large Cap U.S. Equities

While market sentiment on U.S. large caps turns cautious, our Chief CIO and U.S. Equity Strategist Mike Wilson explains why there's still room to stay constructive.Read more insights from Morgan Stanley.----- Transcript -----Welcome to Thoughts on the Market. I'm Mike Wilson, Morgan Stanley’s CIO and Chief U.S. Equity Strategist. Today on the podcast, I’ll be discussing why we remain more constructive than the consensus on large cap U.S. equities – and which sectors in particular. It's Monday, June 16th at 9:30am in New York. So, let’s get after it. We remain more constructive on U.S. equities than the consensus mainly because key gauges we follow are pointing to a stronger earnings backdrop than others expect over the next 12 months. First, our main earnings model is showing high-single-digit Earnings Per Share growth over the next year. Second, earnings revision breadth is inflecting sharply higher from -25 percent in mid-April to -9 percent today. Third, we have a secondary Earnings Leading model that takes into account the cost side of the equation; and that one is forecasting mid-teens Earnings Per Share growth by the first half of 2026. More specifically, it’s pointing to higher profitability due to cost efficiencies. Interestingly, this was something we heard frequently last week at the Morgan Stanley Financials Conference with many companies highlighting the adoption of Artificial Intelligence to help streamline operations. Finally, the most underappreciated tailwind for S&P 500 earnings remains the weaker dollar which is down 11 percent from the January highs. As a reminder, our currency strategists expect another 7 percent downside over the next 12 months. The combination of a stronger level of earnings revisions breadth and a robust rate of change on earnings revisions breadth since growth expectations troughed in mid-April is a powerful tailwind for many large cap stocks, with the strongest impact in the Capital Goods and Software industries. These industries have compelling structural growth drivers. For Capital Goods, it’s tied to a renewed focus on global infrastructure spending. The rate of change on capacity utilization is in positive territory for the first time in two and a half years and aggregate commercial and industrial loans are growing again, reaching the highest level since 2020. The combination of structural tech diffusion and a global infrastructure focus in many countries is leading to a more capital intensive backdrop. Bonus depreciation in the U.S. should be another tailwind here – as it incentivizes a pickup in equipment investment, benefitting Capital Goods companies most directly. Meanwhile, Software is in a strong position to drive free cash flow via GenAI solutions from both a revenue and cost standpoint. Another sector we favor is large cap financials which could start to see meaningful benefits of de-regulation in the second half of the year. The main risk to our more constructive view remains long term interest rates. While Wednesday's below consensus consumer price report was helpful in terms of keeping yields contained, we find it interesting that rates did not fall on Friday with the rise in geopolitical tensions. As a result, the 10-year yield remains in close distance of our key 4.5 percent level, above which rate sensitivity should increase for stocks. On the positive side, interest rate volatility is well off its highs in April and closer to multi-year lows. Our long-standing Consumer Discretionary Goods underweight is based on tariff-related headwinds, weaker pricing power and a late cycle backdrop, which typically means underperformance of this sector. Staying underweight the group also provides a natural hedge should oil prices rise further amid rising tensions in the Middle East. We also continue to underweight small caps which are hurt the most from higher oil prices and sticky interest rates. These companies also suffer from a weaker dollar via higher costs and a limited currency translation benefit on the revenue side given their mostly domestic operations. Finally, the concern that comes up most frequently in our client discussions is high valuations. Our more sanguine view here is based on the fact that the rate of change on valuation is more important than the level. In our mid-year outlook, we showed that when Earnings Per Share growth is above the historical median of 7 percent, and the Fed Funds Rate is down on a year-over-year basis, the S&P 500's market multiple is up 90 percent of the time, regardless of the starting point. In fact, when these conditions are met, the S&P's forward P/E ratio has risen by 9 percent on average. Therefore, our forecast for the market multiple to stay near current levels of 21.5x could be viewed as conservative. Should history repeat and valuations rise 10 percent, our bull case for the S&P 500 over the next year becomes very achievable. Thanks for tuning in; I hope you found this episode informative and useful. Let us know what you think by leaving us a review; and if you find Thoughts on the Market worthwhile, tell a friend or colleague to try it out!

16 Juni 5min

The Economic Stakes of President Trump’s Immigration Policy

The Economic Stakes of President Trump’s Immigration Policy

Our economists Michael Gapen and Sam Coffin discuss how a drop in immigration is tightening labor markets, and what that means for the U.S. economic outlook and Fed policy. Read more insights from Morgan Stanley.----- Transcript -----Michael Gapen: Welcome to Thoughts on the Market. I'm Michael Gapen, Morgan Stanley's Chief U.S. Economist.Sam Coffin: And I'm Sam Coffin, Senior Economist on our U.S. Economics research team.Michael Gapen: Today we're going to have a discussion about the potential economic consequences of the administration’s shift in immigration policies. In particular, we’ll focus much of our attention on the influence that immigration reform is having on the U.S. labor market. And what it means for our outlook on Federal Reserve policy.It's Friday, June 13th at 9am in New York.So, Sam, news headlines have been dominated by developments in the President's immigration policies; what is being called by, at least some commentators, as a toughening in his stance.But I'd like to set the stage first with any new information that you think we've received on border encounters and interior removals. The administration has released new data on that recently that covered at least some of the activity earlier this year. What did it tell you? And did it differ markedly from your expectations?Sam Coffin: What we saw at first was border encounters falling sharply to 30,000 a month from 200,000 or 300,000 a month last year. It was perhaps a surprise that they fell that sharply. And on the flip side, interior removals turned out to be much more difficult than the administration had suggested. They'd been targeting maybe 500,000 per year in removals, 1500 a day. And we're hitting a third or a half of that pace.Michael Gapen: So maybe the recent escalation in ICE raids could be in response to this, right? The fact that interior removals have not been as large as some in the administration would desire.Sam Coffin: That's correct. And we think those efforts will continue. The House Budget Reconciliation Bill, for example, has about $155 billion more in the budget for ICE, a large increase over its current budget. This will likely mean greater efforts at interior removals. About half of it goes to stricter border enforcement. The other half goes to new agents and more operations. We'll see what the final bill looks like, but it would be about a five-fold increase in funding.Michael Gapen: Okay. So much fewer encounters, meaning fewer migrants entering the U.S., and stepped-up enforcement on interior removals. So, I guess, shifting gears on the back of that data. Two important visa programs have also been in the news. One is the so-called CHNV Parole Program that's allowed Cubans, Haitians, Nicaraguans, and Venezuelans to enter the U.S. on parole. The Supreme Court recently ruled that the administration could proceed with removing their immigration status.We also have immigrants on TPS, or Temporary Protected Status, which is subject to periodic removal; if the administration determines that the circumstances that warranted their immigration into the U.S. are no longer present. So, these would be immigrants coming to the U.S. in response to war, conflict, environmental disasters, hurricanes, so forth.So, Sam, how do you think about the ramping up of immigration controls in these areas? Is the end of these temporary programs important? How many immigrants are on them? And what would the cancellation of these mean in terms of your outlook for immigration?Sam Coffin: Yeah, for CHNV Paroles, there are about 500,000 people paroled into the U.S. The Supreme Court ruled that the administration can cancel those paroles. We expect now that those 500,000 are probably removed from the country over the next six months or so. And the temporary protected status; similarly, there are about 800,000 people on temporary protected status. About 600,000 of them have their temporary status revoked at this point or at least revoked sometime soon. And it looks like we'll get a couple hundred thousand in deportations out from that program this year and the rest next year.The result is net immigration probably falling to 300,000 people this year. We'd expected about a million, when we came into this year, but the faster pace of deportation takes that down. So, 300,000 this year and 300,000 next year, between the reduction in border encounters and the increase in deportations.Michael Gapen: So that's a big shift from what we thought coming into the year. What does that mean for population growth and growth in the labor force? And how would this compare – just put it in context from where we were coming out of the pandemic when immigration inflows were quite large.Sam Coffin: Yeah. Population growth before the pandemic was running 0.5 to 0.75 percent per year. With the large increase in immigration, it accelerated 1-1.25 percent during the years of the fastest immigration. At this point, it falls by about a point to 0.3-0.4 percent population growth over the next couple of years.Michael Gapen: So almost flat growth in the labor force, right? So, translate that into what economists would call a break-even employment rate. How much employment do you need to push the unemployment rate down or push the unemployment rate up?Sam Coffin: Yeah, so last year – I mean, we have the experience of last year. And last year about 200,000 a month in payroll growth was consistent with a flat unemployment rate. So far this year, that's full on to 160,000-170,000 a month, consistent with a flat unemployment rate. With further reduction in labor force growth, it would probably decline to about 70,000 a month. So much slower payrolls to hold the unemployment rate flat.Michael Gapen: So, as you know, we've taken the view, Sam, that immigration controls and restrictions will mean a few important things for the economy, right? One is fewer consuming households and softening demand, but the foreign-born worker has a much higher participation rate than domestic workers; about 4 to 5 percentage points higher.So, a lot less labor force growth, as you mentioned. How have these developments changed your view on exactly how hard it's going to be to push the unemployment rate higher?Sam Coffin: So, so far this year, payrolls have averaged about 140,000 a month, and the unemployment rate's been going sideways at 4.2 percent. It's been going sideways since – for about nine months now, in fact. We do expect that payroll growth slows over the course of this year, along with the slowing in domestic demand. We have payroll growth falling around 50,000 a month by late in the year; but the unemployment rate going sideways, 4.3 percent this year because of that decline in breakeven payrolls.For next year, we also have weak payroll growth. We also expect weak payroll growth of about 50,000 a month. But the unemployment rate rising somewhat more to 4.8 percent by the end of the year.Michael Gapen: So, immigration controls really mean the unemployment rate will rise, but less than you might expect and later than you might expect, right? So that's I guess what we would classify as the cyclical effect of immigration.But we also think immigration controls and a much slower growth in the labor force means downward pressure on potential. Where are we right now in terms of potential growth and where's that vis-a-vis where we were? And if these immigration controls go into place, where do we think potential growth is going?Sam Coffin: Well, GDP potential is measured as the sum of productivity growth and growth in trend hours worked. The slower immigration means slower labor force growth and less capacity for hours. We estimated potential growth between 2.5 and 3 percent growth in 2022 to 2024. But we have it falling to 2.0 percent presently – or back to where it was before COVID. If we're right on immigration going forward and we see those faster deportations and the continued stoppage at the border, it could mean potential growth of only 1.5 percent next year.Michael Gapen: That’s a big change, of course, from where the economy was just, you know, 12 to 18 months ago. And I'd like to circle back to one point that you made in bringing up the recent employment numbers. In the May job report that was released last week, we also saw a decline in labor force participation. It went down two-tenths on the month.Now, on one hand that may have prevented a rise in the unemployment rate. It was 4.2 but could have been maybe 4.5 percent or so – had the participation rate held constant. So maybe the labor market weakened, and we just don't know it yet. But you have an idea that you've put forward in some of our reports that there might be another explanation behind the drop in the participation rate. What is that?Sam Coffin: It could be that the threat of increased deportations has created a chilling effect on the participation rate of undocumented workers.Michael Gapen: So, explain to listeners what we mean by a chilling effect in participation, right? We're not talking about restricting inflows or actual deportations. What are we referring to?Sam Coffin: Perhaps undocumented workers step out of the workforce temporarily to avoid detection, similar to how people stayed out of the workforce during the pandemic because of fear of infection or need to take care of children or parents. If this is the case, some of the foreign-born population may be stepping out of the labor force for a longer period of time.Michael Gapen: Right. Which would mean the unemployment rate at 4.2 percent is real and does not mask weakness in the labor market. So, whether it's less in migration, more interior removals, or a chilling effect on participation, then the labor market still stays tight.Sam Coffin: And this is why we think the Fed moves later but ultimately cuts more. It's a combination of tariffs and immigration.Michael Gapen: That's right. So, our baseline is that tariffs push inflation higher first, and so the Fed sees that. But if we're right on immigration and your forecast is that the unemployment rate finishes the year at 4.3, then the Fed just stays on hold. And it's not until the unemployment rate starts rising in 2026 that the Fed turns to cuts, right. So, we have cuts starting in March of next year. And the Fed cutting all the way down to 250 to 275.Well, I think altogether, Sam, this is what we know now. It's certainly a fluid situation. Headlines are changing rapidly, so our thoughts may evolve over time as the policy backdrop evolves. But Sam, thank you for speaking with me.Sam Coffin: Thank you very much.Michael Gapen: And thanks for listening. If you enjoy the show, please leave us a review wherever you listen and share Thoughts on the Market with a friend or colleague today.

13 Juni 10min

Midyear Credit Outlook: Slowdown in Europe

Midyear Credit Outlook: Slowdown in Europe

Our analysts Andrew Sheets and Aron Becker explain why European credit markets’ performance for the rest of 2025 could be tied to U.S. growth.Read more insights from Morgan Stanley.----- Transcript -----Andrew Sheets: Welcome to Thoughts on the Market. I'm Andrew Sheets, Head of Corporate Credit Research at Morgan Stanley.Aron Becker: And I'm Aron Becker, Head of European Credit Strategy.Andrew Sheets: And today on the program, we're continuing a series of conversations covering the outlook for credit around the world. Morgan Stanley has recently updated its forecast for the next 12 months, and here we're going to bring you the latest views on what matters for European credit.It's Thursday, June 12th at 2pm in London.So, Aron, it's great to have this conversation with you. Today we're going to be talking about the European credit outlook. We talked with our colleague Vishwas in the other week about the U.S. credit outlook. But let's really dive into Europe and how that looks from the perspective of a credit investor.And maybe the place to start is, from your perspective, how do you see the economic backdrop in Europe, and what do you think that means for credit?Aron Becker: Right. So, on the European side, our growth expectations remain somewhat more challenging. Our economists are expecting growth after a fairly strong start to slow down in the back half of this year. The German fiscal package that was announced earlier this year will take time to lift growth further out in 2026. So, in the near term, we see a softening backdrop for the domestic economy.But I think what's important to emphasize here is that U.S. growth, as Vishwas and you have talked about last time around, is also set to decelerate on our economists forecast more meaningfully. And that matters for Europe.Two reasons why I think the U.S. growth outlook matters for European credit. One, nearly a quarter of European companies’ revenues are generated in the U.S. And two, U.S. companies themselves have been very actively tapping the European corporate bond markets. And in fact, if you look at the outstanding notion of bonds in the euro benchmarks, the largest country by far is U.S. issuers. And so, I do think that we need to think about the outlook on the macro side, more in a global perspective, when we think about the outlook for European credit. And if we look at history, what we can deduct from the simple correlation between growth and credit spreads is current credit valuations imply growth would be around 3 percent. And that's a stark contrast to our economists’ forecast where both Europe and U.S. is decelerating to below 1 percent over the next 12 months.Andrew Sheets: But Aron, you know, you talked about the slow growth, here in Europe. You talked about a slower growth picture in the U.S. You talked about, you know, pretty extensive exposure of European companies into the U.S. story. All of which sound like pretty challenging things. And yet, if one looks at your forecasts for credit spreads, we think they remain relatively tight, especially in investment grade.So, how does one square that? What's driving what might look like, kind of, a more optimistic forecast picture despite those macro challenges?Aron Becker: Right. That's a very important question. I think that it's not all about the growth, and there are a number of factors that I think can alleviate the pressures from the macro side. The first is that unlike in the U.S., in Europe we are expecting inflation to decelerate more meaningfully over the coming year. And we do think that the ECB and the Bank of England will continue to ease policy. That's good for the economy and the eventual rebound. And we also think that it's good for demand for credit products. For yield buyers where the cash alternative is getting less and less compelling, I think they will see yields on corporate credit much more attractive. And I do think that credit yields right now in Europe are actually quite attractive.Andrew Sheets: So, Aron, you know, another question I had is, if you think about some of those dynamics. The fact that interest rates are above where they've been over the last 10 years. You think about a growth environment in Europe, which is; it's not a recession, but growth is, kind of, 1 percent or a little bit below.I mean, some ways this is very similar to the dynamic we had last year. So, what do you think is similar and what do you think is different, in terms of how investors should think about, say, the next 12 months – versus where we've been?Aron Becker: Right. So, what's really similar is, for example, the yield, like I just mentioned. I think the yield is attractive. That hasn't really changed over the past 12 months. If you just think about credit as a carry product, you're still getting around between 3-3.5 percent on an IG corporate bond today.What's really different is that over the same period, the ECB has already lowered front-end rates by 200 basis points. And at the same time, if you think about the fiscal developments in Germany or broader rates dynamics, we've seen a sharp steepening of yield curves; and curves are actually at the steepest levels in two years now. And what this leaves us with is not only high carry from the yield on corporate bonds, but also investors are now rolling down on a much steeper curve if they buy bonds today, especially further out the curve.So, by our estimate, if you aggregate the two figures in terms of your expected total return, credit offers actually total returns much higher than over the past 12 months, and closer to where we were in the LDI crisis in 2022.Andrew Sheets: So, Aron, another development I wanted to ask you about is, if you look at our forecast for the year ahead, our global forecast. One theme is that on the government side there's projected to be a lot more borrowing. There's more borrowing in Germany, and then there's more borrowing in the U.S., especially under certain versions of the current budget proposals being debated. So, you know, it does seem like you have this contrast between more borrowing and kind of a worsening fiscal picture in governments, a better fiscal picture among corporates. We talk about the spread. The spread is the difference between that corporate and government borrowing.So, I guess looking forward first, do you think European companies are going to be borrowing more money? And certainly more money on a relative, incremental basis at these yield levels, which are higher than what they're used to in the past. And, secondly, how do you think about the relative valuation of European credit versus some of the sovereign issuers in Europe, which is often a debate that we'll have with investors?Aron Becker: Big picture? We have seen companies be very active in tapping the corporate bond markets this year. We had a record issuance in May in terms of supply. Now I would push back on the view that that's negative for investors, and expectations for spreads to widen as a result for a number of reasons. One is a lot of gross issuance tends to be good for investors who want to pick up some new issue premiums – as these new bonds do come a little bit cheap to what's out there in terms of available secondary bonds.And second, it creates a lot of liquidity for investors to actually deploy capital, when they do want to enter the bond market to invest. And what we really need to remember here is all this strong issuance activity is coming against very high maturing, volumes of bonds. Redemptions this year are rising by close to 20 percent versus last year. And so, even though we are projecting this year to be a record year for growth issuance from investment grade companies, we think net supply will be lower year-on-year as a result of those elevated, maturities.So overall, I think that's going to be a fairly positive technical backdrop. And as you alluded to it, that's a stark contrast to what the sovereign market is facing at the moment.Andrew Sheets: So, on that net basis, on the amount that they're issuing relative to what they're paying back, that actually is probably looking lower than last year, on your numbers.Aron Becker: Exactly.Andrew Sheets: And finally, Aron, you know, so we've talked a bit about the market dynamics, we've talked about the economic backdrop, we've talked about the issuance backdrop. Where does this leave your thoughts for investors? What do you think looks, kind of, most attractive for those who are looking at the European credit space?Aron Becker: Opportunities are abound, but I think you need to be quite selective of where to actually increase your risk exposure, in my view. One part which we are quite out of consensus on here at Morgan Stanley is our recommendation in European credit to extend duration further out the curve.This goes back to the point I made earlier, that curves are very steep and a lot of that carry and roll down that I think look particularly attractive; you do need to extend duration for that. But there are a number of reasons why I think that that type of trade can work in this backdrop.For one, like I said, valuations are attractive. Two, I also think that from an issuer perspective, it is expensive to tap very long dated bonds now because of that yield dynamic, and I don't necessarily see a lot of supply coming through further out the curve. Three, our rates team do expect curves to bull steepen on the rate side and historically that has tended to favor excess returns further out the curve.And fourth is, a word we love to throw around – convexity. Cash prices further out the curve are very low in investment grade credit. That tends to be actually quite attractive because then even if you get the name wrong, for example, and there are some credit challenges down the line for some of these issuers, your loss given default may be more muted if you entered the bond at a lower cash price.Andrew Sheets: Aron, thanks for taking the time to talk.Aron Becker: Thanks, Andrew. Andrew Sheets: And to our listeners, thank you for sharing a few minutes of your day with us. If you enjoy the show, leave us a review wherever you listen to this podcast and share Thoughts on the Market with a friend or colleague today.

12 Juni 9min

What the New Tax Bill Means for Cross-Border Portfolios

What the New Tax Bill Means for Cross-Border Portfolios

Our Global Head of Fixed Income Research and Public Policy Strategy Michael Zezas reads the fine print of U.S. tax legislation to understand how it might affect foreign companies operating in the U.S. and foreign investors holding U.S. debt.Read more insights from Morgan Stanley.----- Transcript -----Welcome to Thoughts on the Market. I’m Michael Zezas, Global Head of Fixed Income Research and Public Policy Strategy. Today we're talking about a proposal tucked away in U.S. tax legislation that could impact investors in meaningful ways: Section 899.It’s Wednesday, June 11th, at 12 pm in New York. So, Section 899 is basically a new rule that's part of a bigger bill that passed the House. It would give the U.S. Treasury the power to hit back with taxes on foreign companies if they think other countries are unfairly taxing U.S. businesses. And this rule could override existing tax agreements between countries, even applying to government funds and pension plans.The immediate concern is whether foreign holdings of U.S. bonds would be taxed – something that’s not entirely clear in the draft language. Making the costs of ownership higher would affect holders of tens of trillions of U.S. securities. That includes about 25 percent of the U.S. corporate bond market. In short, the concern is that this would disincentivize ownership of U.S. bonds by overseas investors, creating extra costs or risk premium – meaning higher yields. The good news is that there's a decent chance the Senate will tweak or clarify Section 899. Consider the evidence that the motive of those who drafted this provision doesn’t seem to have been to tax fixed income securities. If it was, you’d expect the official estimates of how much tax revenue this provision would generate to be far higher than what was scored by Congress. Public comments by Senators seem to mirror this, signaling changes are coming. But while that might mitigate one acute risk associated with 899, other risks could linger. If the provision were enacted, it acts as an extra cost on foreign multinationals investing in building businesses in the U.S. That means weaker demand for U.S. dollars overall. So while this is not at the core of our FX strategy team’s thesis on why the dollar weakens further this year, it does reinforce the view. For European equities, our equity strategy team flags that Section 899 adds a whole new layer of worry on top of the tariff concerns everyone's been talking about. While people have been focused on European goods exports to the U.S., Section 899 could affect a much broader range of European companies doing business in America. The most vulnerable sectors include Business Services, Healthcare, Travel & Leisure, Media, and Software – basically, any European company with significant U.S. business.The bottom line, even if modified, if section 899 stays in the bill and is enacted, there’s key ramifications for the U.S. dollar and European stocks. But pay careful attention in the coming days. The provision could be jettisoned from the Senate bill. It's still possible that it's too big of a law change to comply with the Senate’s budget reconciliation procedure, and so would get thrown out for reasons of process, rather than politics. We’ll be tracking it and keep you in the loop.Thanks for listening. If you enjoy Thoughts on the Market please leave us a review. And tell your friends. We want everyone to listen.

11 Juni 3min

How China Is Rewriting the AI Code

How China Is Rewriting the AI Code

Our Head of Asia Technology Research Shawn Kim discusses China's distinctly different approach to AI development and its investment implications.Read more insights from Morgan Stanley.----- Transcript -----Welcome to Thoughts on the Market. I’m Shawn Kim, Head of Morgan Stanley’s Asia Technology Team. Today: a behind-the-scenes look at how China is reshaping the global AI landscape. It’s Tuesday, June 10 at 2pm in Hong Kong. China has been quietly and methodically executing on its top-down strategy to establish its domestic AI capabilities ever since 2017. And while U.S. semiconductor restrictions have presented a near-term challenge, they have also forced China to achieve significant advancements in AI with less hardware. So rather than building the most powerful AI capabilities, China’s primary focus has been on bringing AI to market with maximum efficiency. And you can see this with the recent launch of DeepSeek R1, and there are literally hundreds of AI start-ups using open-source Large Language Models to carve out niches and moats in this AI landscape. The key question is: What is the path forward? Can China sustain this momentum and translate its research prowess into global AI leadership? The answer hinges on four things: its energy, its data, talent, and computing. China’s centralized government – with more than a billion mobile internet users – possess enormous amounts of data. China also has access to abundant energy: it built 10 nuclear power plants just last year, and there are ten more coming this year. U.S. chips are far better for the moment, but China is also advancing quickly; and getting a lot done without the best chips. Finally, China has plenty of talent – according to the World Economic Forum, 47 percent of the world’s top AI researchers are now in China. Plus, there is already a comprehensive AI governance framework in place, with more than 250 regulatory standards ensuring that AI development remains secure, ethical, and strategically controlled. So, all in all, China is well on its way to realizing its ambitious goal of becoming a world leader in AI by 2030. And by that point, AI will be deeply embedded across all sectors of China’s economy, supported by a regulatory environment. We believe the AI revolution will boost China’s long-term potential GDP growth by addressing key structural headwinds to the economy, such as aging demographics and slowing productivity growth. We estimate that GenAI can create almost 7 trillion RMB in labor and productivity value. This equals almost 5 percent of China’s GDP growth last year. And the investment implications of China’s approach to AI cannot be overstated. It’s clear that China has already established a solid AI foundation. And now meaningful opportunities are emerging not just for the big players, but also for smaller, mass-market businesses as well. And with value shifting from AI hardware to the AI application layer, we see China continuing its success in bringing out AI applications to market and transforming industries in very practical terms. As history shows, whoever adopts and diffuses a new technology the fastest wins – and is difficult to displace. Thanks for listening. If you enjoy the show, please leave us a review wherever you listen and share Thoughts on the Market with a friend or colleague today.

10 Juni 3min

U.S. Financials Conference: Three Key Themes to Watch

U.S. Financials Conference: Three Key Themes to Watch

Our analysts Betsy Graseck, Manan Gosalia and Ryan Kenny discuss the major discussions they expect to highlight Morgan Stanley’s upcoming U.S. Financials conference.Read more insights from Morgan Stanley.----- Transcript -----Betsy Graseck: Welcome to Thoughts on the Market. I'm Betsy Graseck, Morgan Stanley's U.S. Large Cap Bank Analyst and Morgan Stanley's Global Head of Banks and Diversified Finance Research. Today we take a look at the key debates in the U.S. financials industry. It’s Monday, June 9th at 10:30am in New York.Tomorrow Morgan Stanley kicks off its annual U.S. Financials Conference right here in New York City. We wanted to give you a glimpse into some of the most significant themes that we expect will be addressed at the conference. And so, I'm here with two of my colleagues, Manan Gosalia, U.S. Midcap Banks Analyst, and Ryan Kenny, U.S. Midcaps Advisor Analyst.Investors are grappling with navigating economic uncertainty from new tariff policies, inflation concerns, and immigration challenges – all of which impacts financial growth and credit quality. On the positive side, they are also looking closely at regulatory shifts under the Trump administration, which could ease banking rules for the first time since the Great Financial Crisis.Let's hear what our experts are expecting. Manan, ahead of the conference, what key themes do you expect mid-cap banks will highlight?Manan Gosalia: So, there are three key themes that we've been focused on for the mid-cap banks: loan growth, net interest margins, and capital. So, first on loan growth. Loan growth for the regional banks has been fairly tepid at about 2 to 3 percent year-on-year, and the tone from bank management teams has been fairly mixed in the April earning season that followed the tariff announcements on April 2nd. Some banks were starting to see the uncertainty weigh on corporate decision making and borrowing activity, while others were only seeing a slow down in some parts of their portfolio, with a pickup in other parts. Now that we've had two months to digest the announcements and several more positive developments on tariff negotiations, we expect that the tone from bank management teams will be more positive. Now, we don't expect them to say growth is accelerating, but we do expect that they will say loan growth is holding up with strong pipelines. On the second topic, net interest margins, we expect to hear that there is still room for margin expansion as we go through this year. And that's coming in two places, particularly as bank term deposits continue to reprice lower. And then the back book of fixed rate loans and securities, essentially assets that were put on the books four to five years ago when rates were a lot lower, are now rolling over at today's higher rates. Betsy Graseck: So, is the long end of the curve going up a good thing?Manan Gosalia: Yes, for net interest margins. But on the flip side, the tenure going up is slightly negative for bank capital. So that brings me to my third theme. The regional banks are overall in a much better place on capital than they were two years ago. Balance sheets have improved. Capital levels remain solid across the sector. But the recent increase in the long end of the curve is marginally negative for capital, given that there will be a higher negative mark on securities that banks hold. But we believe that higher capital levels that regional banks have accumulated over the past couple of years will help cushion some of these negative marks, and we don't expect the recent shift in the tenure will have a meaningful impact on bank capital plans.Betsy Graseck: So, the increase in the 10-year pulls down capital a little bit, but not enough to trip any regulatory minimums?Manan Gosalia: Correct.Betsy Graseck: So, all in the 10-year yield going up is a good thing?Manan Gosalia: It's slightly negative, but I would expect it does not impact bank growth plans. Betsy Graseck: Okay. All in, what's the message from mid-cap banks?Manan Gosalia: All in, I would expect the tone to be a little more positive than the banks had at April earnings.Betsy Graseck: Excellent. Thanks so much, Manan. Ryan, what about you? What are you expecting mid-cap advisors will say?Ryan Kenny: So, I think we'll hear a lot about the trends in M&A. And when we last heard from investment bank management teams during April earnings, the messaging was more cautious. We heard about M&A deals being paused as companies processed the Liberation Day tariffs, and a small number of deals being pulled. Tomorrow at our conference, expect to hear a measured but slightly improved tone. Look, there's still a lot of uncertainty out there, but what's changed since April is the fact that the U.S. administration is flexing in response to markets. So that should help shore up more confidence needed to do deals, and there's tremendous pent-up demand for corporate activity. Over the last three years – so 2022 to 2024 – M&A volumes relative to nominal GDP have been running 30 to 40 percent below three-decade averages. Equity capital markets volumes 50 to 60 percent below average. There is tremendous need for private equity firms to exit their portfolio investments and deploy $4 trillion of dry powder that has accumulated and also structural themes for corporates – like the need for AI capabilities, energy and biotech consolidation and reshoring – that should fuel mergers as a cycle gets going.So, I think for this group, the message will likely be: April and May – more challenged from a deal flow perspective; but back up of the year, you should start to expect some improvement.Betsy Graseck: So slightly improved tone…Ryan Kenny: Slightly improved. And one of the other really interesting themes that the investment banks will talk about is the substantial growth of private capital advisory.So, this is advising private equity funds and owners on capital raising, liquidation, including secondary transactions and continuation funds. And what will be interesting is how the clients set here is growing. We've seen this quarter, major universities, some local governments that increasingly need liquidity and they're hiring investment banks to advise on selling private equity fund interests.It's really going to be a great discussion because private capital advisory is a major growth area for the boutique investment banks that I cover.Betsy Graseck: How big of a sleeve do you think this could become – as big as M&A outright?Ryan Kenny: Probably not as big as M&A outright, but significant. And it helps give the investment banks’ relationships with financial sponsors who are active on the M&A front. So, it can be a share gain story.So, Betsy, what about you? You cover the large cap banks. What do you expect to hear?Betsy Graseck: Well, before I answer that, I do want to just put a pin on it.So, you're saying that for your coverage Ryan, we have some green shoots coming through...Ryan Kenny: Yeah, green shoots and more positive than in April.Betsy Graseck: And Manan on your side? Same?Manan Gosalia: A little bit more of a positive than April earnings, but more of the same as we heard at the start of the year.Betsy Graseck: Okay. Going back to the future then, I suppose we could say. Excellent. Well on large cap banks, I do expect large cap banks will be reflecting some of the same themes that you both just discussed. In particular, you know, we'll talk about IPOs. IPOs are holding up. We look at IPOs where we had 26 IPOs in the past week alone.That's up from 22 on average year-to-date in 2025. And I do think that the large cap banks will highlight that capital market activity is building and can accelerate from here, as long as equity volatility remains contained. By which we mean VIX is at 20 or below. And with capital market activity should come increased lending activity. It's very exciting. What's going on here is that when you do an M&A, you have to finance it, and that financing comes from either the bond market or banks or private credit. M&A financing is a key driver of CNI loan growth. A lot of people don't know that. And CNI loan growth, we do think will be moving from current levels of about 2 percent year-on-year, as per the most recent Fed H.8 data to 5 percent as M&A comes through over the next year plus. And then the other major driver of CNI loans is loans to non-depository financial institutions, which is also known as NDFI Loans. NDFI loans have been getting a lot of press recently. We see this as much ado about reclassification. That said, investors are asking what is the risk of this book of business? Our view is that it's similar to overall CNI loan risk, and we will dig into that outlook with managements at the conference. It'll be exciting. Additionally, we will touch on regulation and how easing of regulation could change strategies for capital utilization and capital deployment. So, you want to have an ear out for that. Well, Manan, Ryan, it's been great speaking with you today.Manan Gosalia: Should be an exciting conference.Ryan Kenny: Thanks for having us on.Betsy Graseck: And thanks for listening everyone. If you enjoy Thoughts on the Market, please leave us a review wherever you listen and share the podcast with a friend or colleague today.

9 Juni 10min

Standing by Our Outlook

Standing by Our Outlook

Morgan Stanley’s midyear outlook defied the conventional view in a number of ways. Our analysts Serena Tang and Vishy Tirupattur push back on the pushback to their conclusions, explaining the thought process behind their research. Read more insights from Morgan Stanley.----- Transcript -----Serena Tang: Welcome to Thoughts on the Market. I'm Serena Tang, Morgan Stanley's Chief Cross-Asset StrategistVishy Tirupattur: And I'm Vishy Tirupattur, Morgan Stanley's Chief Fixed Income Strategist.Serena Tang: Today's topic, pushback to our outlook.It's Friday, June 6th at 10am in New York.Morgan Stanley Research published our mid-year outlook about two weeks ago, a collaborative effort across the department, bringing together our economist views with our strategist high conviction ideas. Right now, we're recommending investors to be overweight in U.S. equities, overweight in core fixed income like U.S. treasuries, like U.S. IG corporate credit. But some of our views are out of consensus.So, I want to talk to you, Vishy, about pushback that you've been getting and how we pushback on the pushback.Vishy Tirupattur: Right. So, the biggest pushback I've gotten is a bit of a dissonance between our economics narrative and our markets narrative. Our economics narrative, as you know, calls for a significant weakening of economic growth. From about – for the U.S. – 2.5 percent growth in 2024 goes into 1 percent in 2025 and in 2026. And Fed doesn't cut rates in 2025, and cuts seven times in 2026.And if you look at a somewhat uninspiring outlook for the U.S. economy from our economists – reconciling an uninspiring economic outlook on the U.S. economy with the constructive view we have on U.S. assets, equities, credit, treasuries – that's been a source of contention. So how do we reconcile this? So, my pushback to the pushback is the following; that they are different plot lines across different asset classes. So, our economists have slowing of the economy – but not an outright recession. Our economists don't have rate cuts in 2025 but have seven rate cuts in 2026.So, if you look at the total number of rate cuts that are being priced in by the markets today, roughly about two rate cuts in [20]25, and about between two and three rate cuts in 2026, we expect greater policy easing than what's currently priced in the markets. So that makes sense for our constructive view on interest rates, and in government bonds and in duration that makes sense.From a credit point of view, we enter this point with a much better credit fundamentals in leverage and coverage terms. We have the emergence of a total yield-based buyer base, which we think will be largely intact at our expectations, and you layer on top of that – the idea that growth slows but doesn't fall into recession is also constructive for higher quality credit. So that explains our credit view.From an equities view, the drawdowns that we experienced in April, our equity strategists think marks the worst outcomes from a policy point of view that we could have had. That has already happened. So looking forward, they look for EPS growth over the course of the next 12 months. They look for benefits of deregulation to kick in. So, along with that seven rate cuts, get them to be comfortable in being constructive about their views on equities. So all of that ties together.Serena Tang: And I think what you mentioned around macro not being the markets is important here. Because when we did some analysis on historical periods where you had low growth and low inflation, actually in that kind of a scenario equities did fine. And corporate credit did fine. But also, in an environment where you have rather unencouraging growth, that tends to map onto a slightly risk-off scenario. And historically that's also a kind of backdrop where you see the dollar strengthen.This time out, we have a very out of consensus view; not that the dollar will weaken, that seems quite consensus. But the degree of magnitude of dollar weakening. Where have you been getting the most pushback on our expectations for the dollar to depreciate by around 9 percent from here?Vishy Tirupattur: So, the dollar weakness in itself is not out of consensus, largely driven by narrowing of free differentials; growth differentials. I think some of the difference between the extent of weakness that we are projecting comes from the assessment on the policy and certainty. So, the policy uncertainty adds a greater degree of risk premia for taking on U.S. assets.So, in our forecast, we take into account not only the differentials in rates and growth, but also in the policy uncertainty and the risk premia that the investors would demand in the face of that kind of policy uncertainty. And that really explains why we are probably more negative on the outcome for U.S. dollar than perhaps our competition.Serena Tang: The risk premium part, I think bring us to one of the biggest debates we've been having with investors over, not just the last few weeks, but over the last few months. And that is on U.S. exceptionalism. Now clearly, we have a view that U.S. assets can outperform over the next six to 12 months, but why aren't we factoring in higher risk premium for holding any kind of U.S. assets? Why should U.S. assets still do well?Vishy Tirupattur: So, as I said earlier, we are calling for the economy to slow without tipping into recession. We are also calling for greater amount of policy easing than what is currently priced in the markets. Both those factors are constructive.So, I think we also should keep in mind the sheer size of the U.S. markets. The U.S. government bond markets, for example, are 10 times the size of comparably rated European bond markets, government bond markets put together. The U.S. equity markets is four-five times the size of the European equity markets. Same thing for investment grade corporate credit bonds. The market is many, many times larger.So, the sheer size of the U.S. assets makes it very difficult for a globally diversified portfolio to substantially under-allocate to U.S. assets. So, what we are suggesting, therefore, is that allocate to U.S. assets, where there are all these opportunities we described. But if you are not a U.S. investor, hedge the currency risk. Not hedging currency risk had worked in the past, but we are now saying hedge your currency risk.Serena Tang: And the market size and liquidity point is interesting. I think after the outlook was published, we had a lot of questions on this. And I think it's underappreciated, how about, sort of, 60 percent of liquid, high quality fixed income paper is actually denominated in U.S. dollars. So, at the end of the day, or at least over the next six to 12 months, it does seem like there is no alternative.Now Vishy, we've talked a lot about where we are getting pushback. I think that one part of the outlook where – very little discussed because very highly consensus – is credit. And the consensus is credit is boring. So how do you see corporate credit, and maybe securitized credit, fit into the wider allocation views on fixed income?Vishy Tirupattur: Boring is good for a fixed income investor perspective, Serena. Our expectation of rate cuts, slowing growth but not going tipping into recession, and our idea that these spreads are really not going very far from where they are now, gets us to a total return of about over 10 percent for investment related corporate credit.And that actually is a pretty good outcome for credit investors. For fixed income investors in general that calls for continued allocations to high quality credit, in corporate credit as well as in securitized credit.Serena Tang: So just to sum up, Morgan Stanley Research has very differentiated view this time around on how many times the Fed can cut, which is a lot more than what markets are pricing in at the moment, how much yields can fall, and also how much weakening in the U.S. dollar that we can get. We are recommending investors to be overweight U.S. equities and overweight U.S. core fixed income like U.S. treasuries and like U.S. IG corporate credits. And as much as we're not arguing [that] U.S. exceptionalism can continue on forever, over the next six to 12 months, we are constructive on U.S. assets.That is not to say policy uncertainty won't still create bouts of volatility over the next 12 months. But it does mean that during those scenarios, you want to sell U.S. dollars rather than U.S. assets.Vishy, thank you so much for taking the time to talk.Vishy Tirupattur: Great speaking with you, Serena.Serena Tang: And for those tuned in, thanks for listening. If you enjoy Thoughts on the Market, please leave us a review wherever you listen and share the podcast with a friend or colleague today.

6 Juni 9min

5 Reasons the Obesity Drug Market Remains Strong

5 Reasons the Obesity Drug Market Remains Strong

The global market for obesity drugs is expanding. Our U.S. Pharma and Biotech Analyst Terrence Flynn discusses what’s driving the next stage of global growth for GLP-1 medicines.Read more insights from Morgan Stanley.----- Transcript -----Terrence Flynn: Welcome to Thoughts on the Market. I'm Terrence Flynn, Morgan Stanley's U.S. Pharma and Biotech Analyst. The market for obesity medicines is at an inflection point, and today I'll focus on what's driving the next stage of global growth.It's Thursday, June 5th at 2pm in New York.GLP-1 medicines have been viewed by many stakeholders as one of the most transformative medications in the market today. They've exploded in popularity over the last few years and become game changers for many people who take them. These drugs have large cap biopharma companies racing to innovate. They've had ripple effects on food, fitness, and fashion. They truly are a major market force. And now we're on the cusp of a significant broadening of use of these medicines.Currently the U.S. is the largest consumer in the world of GLP-1s. But new versions of these medicines suggest that this market will extend beyond the U.S. to significantly larger numbers of patients globally. On our estimate, the Total Addressable Market or TAM for obesity medications should reach $150 billion globally by 2035, with approximately [$]80 billion from the U.S. and [$]70 billion from international markets.Now this marks a meaningful increase from our 2024 forecast of [$]105 billion and reflects a greater appreciation of opportunities outside of the U.S. We think obesity drug adoption will likely accelerate as patients and providers become more familiar with the new products and as manufacturers address hurdles in production, distribution, and access.Current adoption rates of GLP-1 treatments within the eligible obesity population are about 2 to 3 percent. This is in the U.S., and roughly 1 percent in the rest of the world. Now, when we look out further, we anticipate these figures to surge to 20 percent and 10 percent respectively, really driven by five things.First, after a period of shortages, supply constraints have improved, and the drug makers are investing aggressively to increase production. Second new data show that obesity drugs have broader clinical applications. They can be used to treat coronary heart disease, stroke, hypertension, kidney disease, or even sleep apnea. They could also potentially fight Alzheimer's disease, neuropsychiatric conditions, and even cancer.Third, we think coverage will expand as obesity drugs are approved to treat diseases beyond obesity. Public healthcare coverage through Medicare should also broaden based on these expected approvals. Fourth, some drug makers are successfully developing obesity drugs, in pill form instead of injectables. Pills are of course easier to administer and can reach global scale quickly. And finally, drug makers are also developing next gen medications with even higher efficacy, new mechanisms of action, and more convenient, less frequent dosing.All in all, we think that over the next decade, broader GLP-1 adoption will extend well beyond biopharma. We expect significant impacts on medical technology, healthcare services, and consumer sectors like food, beverages, and fashion, where changes in patient diets could reshape market dynamics.Thanks so much for listening. If you enjoy the show, please leave us a review wherever you listen. And share Thoughts on the Market with a friend or colleague today.

5 Juni 3min

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