#520: pyx - the other side of the uv coin (announcing pyx)
A couple years ago, Charlie Marsh lit a fire under Python tooling with Ruff and then uv. Today he’s back with something on the other side of that coin: pyx. Pyx isn’t a PyPI replacement. Think server...
23 Sep 20251h
#519: Data Science Cloud Lessons at Scale
Today on Talk Python: What really happens when your data work outgrows your laptop. Matthew Rocklin, creator of Dask and cofounder of Coiled, and Nat Tabris a staff software engineer at Coiled join me...
18 Sep 20251h 2min
#518: Celebrating Django's 20th Birthday With Its Creators
Twenty years after a scrappy newsroom team hacked together a framework to ship stories fast, Django remains the Python web framework that ships real apps, responsibly. In this anniversary roundtable w...
29 Aug 20251h 8min
#517: Agentic Al Programming with Python
Agentic AI programming is what happens when coding assistants stop acting like autocomplete and start collaborating on real work. In this episode, we cut through the hype and incentives to define “age...
22 Aug 20251h 17min
#516: Accelerating Python Data Science at NVIDIA
Python’s data stack is getting a serious GPU turbo boost. In this episode, Ben Zaitlen from NVIDIA joins us to unpack RAPIDS, the open source toolkit that lets pandas, scikit-learn, Spark, Polars, and...
19 Aug 20251h 5min
#515: Durable Python Execution with Temporal
What if your code was crash-proof? That's the value prop for a framework called Temporal. Temporal is a durable execution platform that enables developers to build scalable applications without sacrif...
11 Aug 20251h 10min
#514: Python Language Summit 2025
Every year the core developers of Python convene in person to focus on high priority topics for CPython and beyond. This year they met at PyCon US 2025. Those meetings are closed door to keep focused ...
18 Juli 20251h 13min
#513: Stories from Python History
Why do people listen to this podcast? Sure, they're looking for technical explorations of new libraries and ideas. But often it's to hear the story behind them. If that speaks to you, then I have the ...
14 Juli 20251h 8min
