Severe meningoencephalitis in the ICU: results from the EURECA study
Central nervous system (CNS) infections significantly burden ICU physicians' daily clinical work. Diagnosis can be challenging, and timely management is of the utmost importance. Meningoencephalitis i...
6 Sep 202318min
Diabetes mellitus in old critically ill COVID-19 patients
Several studies have found an association between diabetes mellitus, disease severity and outcome in COVID-19 patients. Old, critically ill patients are particularly at risk. A recent multicentre inte...
30 Aug 202310min
Results from the TAME trial
International guidelines recommend targeting normocapnia in adults with coma resuscitated after out-of-hospital cardiac arrest. However, normocapnia may be insufficient to restore and maintain adequat...
27 Juni 202325min
Guidelines for the management of severe community-acquired pneumonia
Severe community‐acquired pneumonia (sCAP) is a clinical entity to describe ICU-admitted patients with community‐acquired pneumonia (CAP) as they might require organ support, and it is associated with...
24 Maj 202320min
Permissive azotemia during AKI enables more rapid renal recovery and less renal fibrosis
Preclinical models of acute kidney injury (AKI) consistently demonstrate that a uremic milieu enhances renal recovery and decreases kidney fibrosis. Reduced renal clearance has the surprising and count...
17 Maj 202343min
How to manage coagulopathies in critically ill patients
Coagulopathy is a severe and frequent complication in critically ill patients, for which the pathogenesis and presentation may be variable depending on the underlying disease. Therefore, a review has ...
10 Maj 202320min
End of Life Care concepts in intensive care
End-of-life care is an approach to a terminally ill patient that shifts the focus of care to symptom control, comfort, dignity, quality of life, and quality of dying rather than treatments aimed at cu...
3 Maj 202330min
Machine-learning-derived sepsis bundle of care
The Surviving Sepsis Campaign (SSC) produces and regularly updates guidelines for managing patients with sepsis and septic shock. However, deviation from guidelines is frequently observed in the inten...
22 Mars 202326min
