Ep. 432 AI in Medicine: Navigating the New Frontier with Confidence with Dr. Matthew Lungren

Interventional Radiologist Christopher Beck talks with Hepatologist Parvez Mantry about the management of Portal Hypertension and Ascites, and the importance of multi-disciplinary collaborative care for these patients. --- SHOW NOTES In this episode, hepatologist Dr. Parvez Mantry joins our host Dr. Christopher Beck to discuss portal hypertension and ascites, two complications that arise from liver diseases and have a large effect on patients’ quality of life. Dr. Mantry starts the episode by sharing statistics on Chronic Liver Disease (CLD) and specifically highlights the burden of CLD on the U.S. population. He discusses various causes of CLD, including Hepatitis C, Alcohol Liver Disease, and Non-Alcoholic Steatohepatitis. Next, Dr. Mantry takes us through his diagnostic workup, including his physical examination, cross-sectional imaging, percutaneous and transjugular liver biopsies, and serological workup. He checks for complications such as portal hypertension, ascites, pedal edema, and hepatic encephalopathy. We also discuss the diagnosis of Hepatocellular Carcinoma (HCC). Then, we transition to strategies for managing ascites and portal hypertension through diuretics, paracentesis, Transjugular Intrahepatic Portosystemic Shunts (TIPS), liver transplantation, and a few experimental treatments that he is currently researching. Overall, Dr. Mantry advocates for close monitoring of symptoms and making treatment modifications as needed. Finally, when focusing on the patient experience, Dr. Mantry offers troubleshooting tips, especially for patients who struggle with leakage from the paracentesis site. To close, he gives insights on how physicians can best support chronically-ill patients who are awaiting transplantation. --- RESOURCES Methodist Transplant Specialists- https://www.theliverinstitutetx.com/ Information about Dr. Mantry’s transplant center and its satellite locations in the Dallas-Ft. Worth Community. American Association for the Study of Liver Diseases (AASLD) Practice Guidelines- https://www.aasld.org/publications/practice-guidelines Management of HCC- https://www.journal-of-hepatology.eu/article/S0168-8278(12)60009-9/pdf The Management of Ascites in Cirrhosis- https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1053/jhep.2003.50315 These are guidelines set by the International Ascites Club. BackTable Pdcast Ep. 123 TIPS University Freshman Year: Referrals and Pre-Op Workup- https://www.backtable.com/shows/vi/podcasts/123/tips-university-freshman-year-referrals-pre-op-workup

17 Maj 202150min

It's Senior Year at TIPS University with Dr. Emmett Lynskey talking us through his Gunsight technique for TIPS placement, as well as how to perform a safe closure of splenic access. Don't miss the first three parts of the series as well! --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn AMA PRA Category 1 CMEs: https://earnc.me/MThuo7 --- SHOW NOTES In this episode, Dr. Emmett Lynskey joins Dr. Chris Beck for the final edition of TIPS University to discuss the gunsight technique and splenic closure. We begin by discussing where to start once the catheter is in the portal vein and you have access, and Dr. Lynskey shares why he likes to use a 8mm balloon for the angioplasty. We explain the details of the gunsight technique, how to line up the portal and hepatic snare, how to adjust the view, and how to get access to both veins using a 22 gauge chiba needle. We share why it is important to make sure that the cranial caudal difference between the portal and hepatic snare is not significant before you gunsight. We discuss how to work with wires to floss through the splenic vein. Dr. Lynskey tells us why he uses a microcatheter for an extra step instead of snaring the end of the wire. We review some situations where you can throw the snare up and stick it with a colapinto needle and some of the considerations for portal vein thrombosis when doing TIPS. We discuss splenic access and why it is important to set up for good closure. We explain the different options for splenic access, using a combination of coils, plugs, and gelfoam, and Dr. Lynskey shares which combinations he prefers to use for splenic closure. We review the technique to get images using fluoro and ultrasound.

14 Maj 202133min

It's Junior Year at TIPS University with Dr. Emmett Lynskey walking through advanced techniques for TIPS, including using Intracardiac Echocardiography (ICE) for placement, as well as transsplenic access for portal reconstruction. --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn AMA PRA Category 1 CMEs: https://earnc.me/Il3qDw --- SHOW NOTES In this episode, Dr. Emmett Lynskey joins Dr. Chris Beck for the third edition of TIPS University to discuss intracardiac echo (ICE) and splenic access in TIPS procedures. We discuss the learning curve associated with ICE and Dr. Lynskey tells us about the early challenges he faced when learning this technique. We share why using ICE is helpful in TIPS and how to set up the procedure, depending on the type of access you want. We explain how to get a more medial throw by getting the catheter closer to the portal vein, and we discuss how to torque the needle for different throws. We discuss making throws using an ICE probe and why ICE is helpful for acutely thrombosed TIPS revisions. Dr. Lynskey tells us about some other good uses for the ICE catheter. We discuss splenic access, and we review the conditions that allow for safe splenic access. We explain how to do the ultrasound evaluation anterior to the probe. Dr. Lynskey shares why he dedicates one hand for the wire and one hand for the ultrasound, and he tells us how he picks the sheaths and wires that he uses to get splenic access. We discuss how to know that you have opened up the splenic vein. --- RESOURCES Edward Jones Financial Advisor Yaphet Tadesse: https://www.edwardjones.com/us-en/financial-advisor/yaphet-tadesse

10 Maj 202157min

It's Sophomore Year at TIPS University with Dr. Emmett Lynskey and Dr. Christopher Beck discussing basic procedure technique for Transjugular Intrahepatic Portosystemic Shunts (TIPS). --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn AMA PRA Category 1 CMEs: https://earnc.me/jfkcyQ --- SHOW NOTES In this episode, Dr. Emmett Lynskey joins Dr. Chris Beck for the second edition of TIPS University to discuss basic TIPS procedure techniques. Dr. Lynskey starts us off by talking through the steps of getting access for a basic TIPS procedure, and he tells us how to check if there is a large difference between wedge pressure and the true portal pressure. Next, we discuss doing a puff or a run of the vein to make sure that there is no obstruction of outflow. Dr Lynskey compares new and old techniques for getting the sheath into the vein, and he explains two different methods, bare back and over the wire, for getting the needle down for the TIPS procedure. We outline what you should expect to see after doing a puff of contrast, how to locate the central portal vein, and the differences between using CO2 and contrast. Dr. Lynskey shares what factors he considers when choosing a wire for TIPS and how he uses a pigtail and a sheath to perform a dual run. We review the purpose of a dual run and discuss the details of opening the tip once the sheath is down. We then compare the final steps of the TIPS procedure based on whether or not you will embolize, and give a brief overview of embolizing using a fogarty balloon. Dr. Lynskey goes over his goal frame rate for the final run of the TIPS, and he explains how to check the flow dynamic of blood going to the liver. He tells us about follow-up care and how it changes if a patient develops encephalopathy. We end the episode by discussing the importance of counseling patients and caretakers on medications.

7 Maj 20211h 4min

We start our TIPS University series with Interventional Radiologist Dr. Emmett Lynskey discussing referral sources and pre-operative workup, including the importance of patient selection and MELD score. --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn AMA PRA Category 1 CMEs: https://earnc.me/GKHtWA --- SHOW NOTES In this episode, Dr. Emmett Lynskey joins Dr. Chris Beck for the first edition of TIPS University to discuss referrals and pre-op for transjugular intrahepatic portosystemic shunts (TIPS). Dr. Lynskey begins by telling us about his fellowship at Georgetown, his current practice, and how he became interested in portal hypertension. We talk through the most common indicators for a TIPS procedure, including refractory ascites, portal vein thrombosis, and acute bleeders. Dr. Lynskey explains how patients are referred to him, and he outlines what factors he considers before determining the eligibility for TIPS. We then discuss how useful cross sectional imaging is, and we break down the Model for End-Stage Liver Disease (MELD) score. Dr. Lynskey shares the components that make up the MELD score as well as the cutoffs and thresholds for a TIPS patient. Next, we review diuretics and emphasize the importance of being honest with patients regarding expectations post-procedure. We explain how to phrase questions when working with cardiologists. Dr. Lynskey goes over what all he can determine from cross-sectional imaging prior to the procedure, and he tells us when he might consider an alternative to TIPS. We discuss which labs should be done the day of the procedure and why Dr. Lynskey gets MELD labs again just before the TIPS. Dr. Lynskey tells us about blood typing, crossmatching, and fibrinogen levels. The episode wraps with Dr. Lynskey explaining the benefits of performing a paracentesis prior to TIPS. --- RESOURCES Edward Jones Financial Advisor Yaphet Tadesse: https://www.edwardjones.com/us-en/financial-advisor/yaphet-tadesse

3 Maj 202143min

Interventional Radiologist Peder Horner talks with Barry Uchida about the early days at The Dotter Institute, with stories about working alongside Josef Rösch on developing the first TIPS sets, as well as working with other legends in the field including Charles Dotter, Fred Keller, and Julio Palmaz.

26 Apr 202147min

Interventional Radiologist Dr. Mike Watts talks with us about which procedures are being safely performed in the OBL space, and the importance of patient selection. --- CHECK OUT OUR SPONSORS Medtronic VenaSeal https://www.medtronic.com/impact Accountable Physician Advisors http://www.accountablephysicianadvisors.com/ Accountable Revenue Cycle Solutions https://www.accountablerevcycle.com/ --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn AMA PRA Category 1 CMEs: https://earnc.me/N4Sfrb --- SHOW NOTES In this episode, Dr. Mike Watts joins Dr. Michael Barraza to discuss Office Based Labs (OBLs). We begin by explaining what an OBL is and how OBLs are different from Ambulatory Surgery Centers (ASC’s). Dr. Watts tells us about some of the advantages of working in an OBL, including reimbursement rates, patient access, and scheduling, and we talk about how the general patient experience is different. Next, we give an overview of how to work with referring doctors at nearby hospitals and build relationships with departments outside of interventional radiology, such as oncology and urology. Dr. Watts shares the advantages of being a full-service IR group, and he tells us how he coordinates patient care between the OBL and hospitals when needed. We also discuss how to expand an OBL practice to become a full-service IR group, how to make yourself valuable within an OBL, and how to participate in ongoing clinical studies. We end the episode with Dr. Watts telling us what is on the horizon for OBLs and what he would like to see in the future.

19 Apr 202137min

Interventional Radiologist Sabeen Dhand talks with Interventional Cardiologist Eric Secemsky about building a Pulmonary Embolism (PE) Response Team, and about the various techniques for treatment of PE used in his practice. --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn AMA PRA Category 1 CMEs: https://earnc.me/8gzIHN --- SHOW NOTES In this episode, interventional cardiologist Dr. Eric Secemsky and our host Dr. Sabeen Dhand discuss pulmonary embolization and the coordination of Pulmonary Embolism Response Teams (PERTs). Dr. Secemsky starts by introducing the diagnosis of pulmonary embolisms. He explains the classification of patients into the categories of massive, submassive, and low-risk embolisms, as well as echocardiogram and CT imaging. His workup includes not only checking for clot burden, but also checking for vital sign abnormalities, evidence of right ventricle dysfunction, and neurological deficits. Then, we transition to talking about the structure, workflow, and communication technologies used in pulmonary embolism response teams. Dr. Secemsky describes his experience with building a response team and ensuring its adaptability for a variety of cases. He emphasizes the importance of multidisciplinary care and team members’ accountability for every patient. Finally, we discuss treatment of pulmonary embolism, based on how emergent a case is. Dr. Secemsky describes factors to consider when employing different treatments: clot extraction devices, thrombolytics, and anticoagulants. Additionally, we cover the topics of catheter-directed thrombolysis, mechanical thrombectomy, and surgical embolectomy. --- RESOURCES Interventional Therapies for Acute Pulmonary Embolism: Current Status and Principles for the Development of Novel Evidence: A Scientific Statement From the American Heart Association- https://www.ahajournals.org/doi/full/10.1161/CIR.0000000000000707 AHA guidelines for the classification of massive, submassive, and low-risk pulmonary embolisms. PERT Consortium- https://pertconsortium.org/ Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism: Consensus Practice from the PERT Consortium- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714903/ SUNSET sPE study- https://vivaphysicians.org/news-article?id=88424

12 Apr 202150min