Maxwell and Grillo on the link between feeding behaviors and leptin activation of dorsal raphe neurons, Fruttiger on microvascular damage and neurodegeneration in early diabetic retinopathy, and Yeo on the genetics of metabolic health.

Welcome to the November 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the November 2024 issue of Diabetes.

3:45 After a quick rundown of our hosts' Halloween plans, this month's episode begins with a special offer from the ADA for new and renewing members: a 15% discount on a 1- or 2-year membership. Go to professional.diabetes.org/membership, create your account, fill out the application, and use the discount code 'FALL24' at checkout. Act fast because this offer expires November 30, 2024!

5:00 Darleen and Kirk speak with Dr. Nicholas Maxwell, postdoctoral fellow at Duke University School of Medicine, and Claudia Grillo, a research associate professor in the Department of Pharmacology, Physiology, and Neuroscience at the University of Southern Carolina School of Medicine in Columbia. They are lead author and corresponding author, respectively, of the article "Leptin Activation of Dorsal Raphe Neurons Inhibits Feeding Behavior." This article is available for free at doi.org/10.2337/db24-0207.

27:05 Our hosts discuss the November issue's Paper of the Month, "Deciphering the Connection Between Microvascular Damage and Neurodegeneration in Early Diabetic Retinopathy." They're joined by senior author, Dr. Marcus Fruttiger, Professor of Experimental Ophthalmology at the Institue of Ophthalmology, University College, London. This study is available at doi.org/10.2337/db24-0107.

50:25 Finally, in honor of World Diabetes Awareness Day on November 14, as well as National Diabetes Month, this month's Sweet Talk segment features Dr. Giles Yeo, a geneticist and obesity researcher from the University of Cambridge. Dr. Yeo discusses how genetic variations contribute to obesity, appetite control, and metabolic health.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!