106 | Stuart Bartlett on What "Life" Means

106 | Stuart Bartlett on What "Life" Means

Someday, most likely, we will encounter life that is not as we know it. We might find it elsewhere in the universe, we might find it right here on Earth, or we might make it ourselves in a lab. Will we know it when we see it? "Life" isn't a simple unified concept, but rather a collection of a number of life-like properties. I talk with astrobiologist Stuart Bartlett, who (in collaboration with Michael Wong) has proposed a new way of thinking about life based on four pillars: dissipation, autocatalysis, homeostasis, and learning. Their framework may or may not become the standard picture, but it provides a useful way of thinking about what we expect life to be.

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Stuart Bartlett received his Ph.D. in complex systems from the University of Southampton. He is currently a postdoctoral researcher in the Division of Geological and Planetary Sciences at Caltech, and was formerly a postdoc at the Earth Life Science Institute at the Tokyo Institute of Technology.


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AMA | June 2025

AMA | June 2025

Welcome to the June 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

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316 | Niayesh Afshordi and Phil Halper

316 | Niayesh Afshordi and Phil Halper

Einstein's general theory of relativity, plus some reasonable assumptions about the universe and what it's made of, has a remarkable implication: that as we trace cosmic evolution into the far past, w...

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315 | Branden Fitelson on the Logic and Use of Probability

315 | Branden Fitelson on the Logic and Use of Probability

Every time you see an apple spontaneously break away from a tree, it falls downward. You therefore claim that there is a law of physics: apples fall downward from trees. But how can you really know? A...

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314 | Karen Lloyd on the Deep Underground Biosphere

314 | Karen Lloyd on the Deep Underground Biosphere

There are living creatures dwelling deep below the surface of the Earth, as deep as we are able to drill. These hearty microorganisms are related to more familiar life forms on land and under water, b...

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313 | Eric Topol on the Changing Face of Medicine and Aging

313 | Eric Topol on the Changing Face of Medicine and Aging

Medical science is advancing at an astonishing rate. Today we talk with leading expert Eric Topol about two aspects of this story. First, the use of artificial intelligence in medicine, especially in ...

5 Maj 20251h 12min

AMA | May 2025

AMA | May 2025

Welcome to the May 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreon...

28 Apr 20253h 38min

312 | Thomas Levenson on the Mutual History of Humans and Germs

312 | Thomas Levenson on the Mutual History of Humans and Germs

The germ theory of disease is a crowning achievement of science, up there with modern physics, continental drift, and evolution via natural selection. (Even if there will always be cranky skeptics.) B...

21 Apr 20251h 31min

311 | Annaka Harris on Whether Consciousness is Fundamental

311 | Annaka Harris on Whether Consciousness is Fundamental

Questions about consciousness range from the precise and empirical -- what neurons fire when I have some particular experience -- to the deeply profound -- does consciousness emerge from matter, or do...

14 Apr 20251h 10min

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