112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

Avsnitt(419)

275 | Solo: Quantum Fields, Particles, Forces, and Symmetries

275 | Solo: Quantum Fields, Particles, Forces, and Symmetries

Publication week! Say hello to Quanta and Fields, the second volume of the planned three-volume series The Biggest Ideas in the Universe. This volume covers quantum physics generally, but focuses espe...

13 Maj 20242h 12min

AMA | May 2024

AMA | May 2024

Welcome to the May 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreon...

6 Maj 20243h 35min

274 | Gizem Gumuskaya on Building Robots from Human Cells

274 | Gizem Gumuskaya on Building Robots from Human Cells

Modern biology is advancing by leaps and bounds, not only in understanding how organisms work, but in learning how to modify them in interesting ways. One exciting frontier is the study of tiny "robot...

29 Apr 20241h 10min

273 | Stefanos Geroulanos on the Invention of Prehistory

273 | Stefanos Geroulanos on the Invention of Prehistory

Humanity itself might be the hardest thing for scientists to study fairly and accurately. Not only do we come to the subject with certain inevitable preconceptions, but it's hard to resist the temptat...

22 Apr 20241h 19min

272 | Leslie Valiant on Learning and Educability in Computers and People

272 | Leslie Valiant on Learning and Educability in Computers and People

Science is enabled by the fact that the natural world exhibits predictability and regularity, at least to some extent. Scientists collect data about what happens in the world, then try to suggest "law...

15 Apr 20241h 8min

AMA | April 2024

AMA | April 2024

Welcome to the April 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patre...

8 Apr 20243h 14min

271 | Claudia de Rham on Modifying General Relativity

271 | Claudia de Rham on Modifying General Relativity

Einstein's theory of general relativity has been our best understanding of gravity for over a century, withstanding a variety of experimental challenges of ever-increasing precision. But we have to be...

1 Apr 20241h 21min

270 | Solo: The Coming Transition in How Humanity Lives

270 | Solo: The Coming Transition in How Humanity Lives

Technology is changing the world, in good and bad ways. Artificial intelligence, internet connectivity, biological engineering, and climate change are dramatically altering the parameters of human lif...

25 Mars 20242h 9min

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