117 | Sean B. Carroll on Randomness and the Course of Evolution

117 | Sean B. Carroll on Randomness and the Course of Evolution

Evolution is a messy business, involving as it does selection pressures, mutations, genetic drift, and the effects of random external interventions. So in the end, how much of it is predictable, and how much is in the hands of chance? Today we're thrilled to have as a guest my evil (but more respectable, by most measures) twin, the biologist Sean B. Carroll. Sean is both a leader of the modern evo-devo revolution, and a wonderful and diverse writer. We talk about the importance of randomness and unpredictability in life, from the evolution of species to the daily routine of every individual.

Support Mindscape on Patreon.

Sean B. Carroll received a Ph.D. in immunology from Tufts University. He is currently the Andrew and Mary Balo and Nicholas and Susan Simon Endowed Chair of Biology at the University of Maryland, Vice-President for Science Education at the Howard Hughes Medical Institute, the Executive Director of HHMI Tangled Bank Studios, and Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin. His new book, A Series of Fortunate Events: Chance and the Making of the Planet, Life, and You, explores the role of chance in the development of life.


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31 | Brian Greene on the Multiverse, Inflation, and the String Theory Landscape

31 | Brian Greene on the Multiverse, Inflation, and the String Theory Landscape

String theory was originally proposed as a relatively modest attempt to explain some features of strongly-interacting particles, but before too long developed into an ambitious attempt to unite all th...

28 Jan 20191h 11min

30 | Derek Leben on Ethics for Robots and Artificial Intelligences

30 | Derek Leben on Ethics for Robots and Artificial Intelligences

It's hardly news that computers are exerting ever more influence over our lives. And we're beginning to see the first glimmers of some kind of artificial intelligence: computer programs have become mu...

21 Jan 20191h 28min

29 | Raychelle Burks on the Chemistry of Murder

29 | Raychelle Burks on the Chemistry of Murder

Sometimes science is asking esoteric questions about the fundamental nature of reality. Other times, it just wants to solve a murder. Today's guest, Raychelle Burks, is an analytical chemist at St. Ed...

14 Jan 20191h 15min

28 | Roger Penrose on Spacetime, Consciousness, and the Universe

28 | Roger Penrose on Spacetime, Consciousness, and the Universe

Sir Roger Penrose has had a remarkable life. He has contributed an enormous amount to our understanding of general relativity, perhaps more than anyone since Einstein himself -- Penrose diagrams, sing...

7 Jan 20191h 35min

Holiday Message 2018

Holiday Message 2018

There won't be any regular episodes of Mindscape this week or next, as we take a holiday break. Regular service will resume on Monday January 7, 2019. In the meantime, here is a special Holiday Messag...

24 Dec 201844min

27 | Janna Levin on Black Holes, Chaos, and the Narrative of Science

27 | Janna Levin on Black Holes, Chaos, and the Narrative of Science

It's a big universe out there, full of an astonishing variety of questions and puzzles. Today's guest, Janna Levin, is a physicist who has delved into some of the trippiest aspects of cosmology and gr...

17 Dec 20181h 8min

26 | Ge Wang on Artful Design, Computers, and Music

26 | Ge Wang on Artful Design, Computers, and Music

Everywhere around us are things that serve functions. We live in houses, sit on chairs, drive in cars. But these things don't only serve functions, they also come in particular forms, which may be emo...

10 Dec 20181h 10min

25 | David Chalmers on Consciousness, the Hard Problem, and Living in a Simulation

25 | David Chalmers on Consciousness, the Hard Problem, and Living in a Simulation

The "Easy Problems" of consciousness have to do with how the brain takes in information, thinks about it, and turns it into action. The "Hard Problem," on the other hand, is the task of explaining our...

3 Dec 20181h 22min

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