88 | Neil Shubin on Evolution, Genes, and Dramatic Transitions

88 | Neil Shubin on Evolution, Genes, and Dramatic Transitions

"What good is half a wing?" That's the rhetorical question often asked by people who have trouble accepting Darwin's theory of evolution by natural selection. Of course it's a very answerable question, but figuring out what exactly the answer is leads us to some fascinating biology. Neil Shubin should know: he is the co-discoverer of Tiktaalik Roseae, an ancient species of fish that was in the process of learning to walk and breathe on land. We talk about how these major transitions happen — typically when evolution finds a way to re-purpose existing organs into new roles — and how we can learn about them by studying living creatures and the information contained in their genomes.

Support Mindscape on Patreon.

Neil Shubin received his Ph.D. in organismic and evolutionary biology from Harvard University. He is currently the the Robert Bensley Distinguished Service Professor and Associate Dean of Biological Sciences at the University of Chicago. He is a member of the National Academy of Sciences and the American Philosophical society. His first book, Your Inner Fish, was chosen by the National Academy of Sciences as the best science book of 2009, and was subsequently made into a TV special. His new book is Some Assembly Required: Decoding Four Billion Years of Life, from Ancient Fossils to DNA.


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336 | Anil Ananthaswamy on the Mathematics of Neural Nets and AI

336 | Anil Ananthaswamy on the Mathematics of Neural Nets and AI

Machine learning using neural networks has led to a remarkable leap forward in artificial intelligence, and the technological and social ramifications have been discussed at great length. To understan...

24 Nov 20251h 14min

AMA | November 2025

AMA | November 2025

Welcome to the November 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

17 Nov 20253h 34min

335 | Andrew Jaffe on Models, Probability, and the Universe

335 | Andrew Jaffe on Models, Probability, and the Universe

Science has an incredibly impressive track record of uncovering nonintuitive ideas about the universe that turn out to be surprisingly accurate. It can be tempting to think of scientific discoveries a...

10 Nov 20251h 17min

334 | Daniel Whiteson on the Physics of and by Aliens

334 | Daniel Whiteson on the Physics of and by Aliens

The universe as revealed by physics is objective: it's out there, existing and behaving in ways that are completely independent of human thought. But the process by which we learn about the universe, ...

3 Nov 20251h 14min

333 | Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them

333 | Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them

Why are people wrong all the time, anyway? Is it because we human beings are too good at being irrational, using our biases and motivated reasoning to convince ourselves of something that isn't quite ...

27 Okt 20251h 10min

332 | Dmitri Tymoczko on the Mathematics Behind Music

332 | Dmitri Tymoczko on the Mathematics Behind Music

Music is math that you can dance to. The fact that certain notes sound good when played together, or in succession, is related to the mathematical properties of the frequencies to which they correspon...

20 Okt 20251h 21min

AMA | October 2025

AMA | October 2025

Welcome to the October 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pat...

13 Okt 20253h 37min

331 | Solo: Fine-Tuning, God, and the Multiverse

331 | Solo: Fine-Tuning, God, and the Multiverse

Certain features of our universe seem unnatural to us. These include "constants of nature" such as the cosmological constant and the mass of the Higgs boson, as well as features of the initial conditi...

6 Okt 20251h 54min

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