First seizure from sleep - What is the risk of recurrence? Dr. Elaine Pang

First seizure from sleep - What is the risk of recurrence? Dr. Elaine Pang

Send comments and feedback Are people who have their first seizure during sleep at greater or lesser risk for future seizures, compared with people who have their first seizure when they're awake? Dr. Laurent Sheybani interviews Dr. Elaine Pang, author of a 2023 paper in Epilepsia that analyzed data from 1,312 adults visiting a first-seizure clinic. This episode also discusses a 2015 evidence-based guideline on managing a first unprovoked seizure in adults. The guideline was developed by the...

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What's new in status epilepticus: Dr. Eugen Trinka

What's new in status epilepticus: Dr. Eugen Trinka

Send comments and feedback This episode covers a wide scope of issues, including treatment options, treatment response, prognosis and the role of seizures versus the underlying etiology, most common e...

4 Aug 202546min

Valproate and reproductive risks in women and men with epilepsy: Dr. Tony Marson

Valproate and reproductive risks in women and men with epilepsy: Dr. Tony Marson

Send comments and feedback In use since the 1970s, valproate is highly effective for genetic generalized epilepsies and some forms of pediatric epilepsy. The medication also is associated with a 10% r...

21 Juli 202522min

ILAE Updated seizure classification: Dr. Sandor Beniczky

ILAE Updated seizure classification: Dr. Sandor Beniczky

Send comments and feedback ILAE's updated seizure classification position paper was published in Epilepsia in April 2025. Sharp Waves talked with Dr. Sandor Beniczky about the updates and how they wil...

7 Juli 202513min

Documentary filmmaker confronts epilepsy in a new memoir: Stacia Kalinoski

Documentary filmmaker confronts epilepsy in a new memoir: Stacia Kalinoski

Send comments and feedback Seizures cost Stacia Kalinoski her career in broadcast journalism and forced her to give up running. In her new memoir, Kalinoski recounts her journey from first seizure in ...

23 Juni 202515min

Work-life balance: Dr. Sheryl Haut

Work-life balance: Dr. Sheryl Haut

Send comments and feedback Work-related stress and burnout are common in physicians, with rates of burnout estimated between 25% and 60%. These stresses impact physician health, patient care, and heal...

9 Juni 202522min

The role of microglia in epilepsy: Hero, villain, or both? Dr. Amy Brewster

The role of microglia in epilepsy: Hero, villain, or both? Dr. Amy Brewster

Send comments and feedback Microglia can have protective and also potentially harmful effects in the brain. They seem to be involved in dampening the nervous system during acute seizures – but also ap...

27 Maj 202519min

Language models reveal concerns of people with epilepsy in online discussions

Language models reveal concerns of people with epilepsy in online discussions

Send comments and feedback Many of the most common concerns of people with epilepsy are topics they don't usually talk about with physicians. This is one of many findings of a study using AI to analyz...

12 Maj 202531min

Music, epilepsy, and the brain: Dr. Phillip Pearl & Prof. Nigel Osborne

Music, epilepsy, and the brain: Dr. Phillip Pearl & Prof. Nigel Osborne

Send comments and feedback Music can affect emotions, spark memories, and influence mood. In cases of musicogenic epilepsy, music can trigger seizures. In other cases, music may reduce seizure frequen...

28 Apr 202526min

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