Episode 171: 171.  Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

Episode 171: 171. Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

SGLT2 inhibitors and GLP1 agonists administered without metformin compared to other glucose‐lowering drugs in patients with type 2 diabetes mellitus to prevent cardiovascular events: A systematic review - Escobar - 2021 - Diabetic Medicine - Wiley Online Library

Yes these fancy new drugs work with and without metformin but that does not mean these drugs should be first line!!


Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network


Yep even 200,000IU of vit D does nothing except raise your vit d level.

Diet and acne: review of the evidence from 2009 to 2020 - Dall’Oglio - - International Journal of Dermatology - Wiley Online Library


What you eat does mess with your acne, or at least says this large observational trial.


Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials | The BMJ

The muscle aches with statins is a common event that it occurs as frequently with the active drug as it does with placebo

Avsnitt(385)

151. Primary Care Providers are Magicians, SGLT2 Inhibitors, and Peanut Allergy

151. Primary Care Providers are Magicians, SGLT2 Inhibitors, and Peanut Allergy

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2771095 SO HOW DO YOU LOSE WEIGHT!! FASTING DOESN’T WORK or so says this study titled- Effects of Time-Restricted Eating on Weight Lo...

26 Okt 202018min

150. Turmeric, Waist vs Weight, Eye Drops, Atrial fibrillation

150. Turmeric, Waist vs Weight, Eye Drops, Atrial fibrillation

Doc my heart is racing— Stop drinking—or so says this article in NEJM that found when they took 140 pts who severed from paroxysmal afib and who drank 17 drinks a week that when randomized to complete...

11 Okt 202018min

149. Rapid Fire- metformin, low-risk annual exams, and medication for the elderly

149. Rapid Fire- metformin, low-risk annual exams, and medication for the elderly

Rapid fire articles- no deep dive. Just good a lot of questioning, questioning medicine. If you want any of the articles for your own review or have any questions you can always reach me at andrewbuel...

6 Okt 202023min

148. Lipids, Cholesterol, Hyperlipidemia--- NEW GUIDELINES!

148. Lipids, Cholesterol, Hyperlipidemia--- NEW GUIDELINES!

We stuck purely to the evidence. There was no evidence panel or committee to vote on the evidence like is often done by the American college of rheumatology and no expert opinion statements where thei...

29 Sep 202019min

147. BONUS! BIG10 and Return To Football

147. BONUS! BIG10 and Return To Football

athlete heart covidhttps://www.the-scientist.com/news-opinion/college-athletes-experienced-heart-damage-after-covid-19-study-67929titiles like- “Images of the players’ hearts showed signs of inflammat...

20 Sep 202016min

146. Fluoroquinolone and Aortic disease, HPV Vaccine, Orthostatic Hypotension

146. Fluoroquinolone and Aortic disease, HPV Vaccine, Orthostatic Hypotension

the thing about RCT is they are random and everything is equal. its why in table one of an RCT you should never see a pvalue because they are random and should be equal but in observational studies yo...

18 Sep 202023min

145. Rosiglitazone, Dr. Mandrola, Ethics committee, GlaxoSmithKline, and the mafia

145. Rosiglitazone, Dr. Mandrola, Ethics committee, GlaxoSmithKline, and the mafia

Finance ethics committee, big pharma with deep pockets, mafia like arrangements, and a patient with a 40% increase risk of ischemia myocardial events have in common?I will say todays podcast was inspi...

13 Sep 202033min

144. COVID, BIG10 FOOTBALL

144. COVID, BIG10 FOOTBALL

In this study of a cohort of German patients recently recovered from COVID-19 infection, CMR revealed cardiac involvement in 78 patients (78%) and ongoing myocardial inflammation in 60 patients (60%),...

3 Sep 202018min

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