Episode 303: 302. Effects of statin therapy on diagnoses of new-onset diabetes

The incidence of new-onset diabetes was basically the same but statistically significantly higher for those individuals on low-to-moderate–intensity statins compared with placebo 1.2 vs 1.3% annually which is a very small difference.

But with high-intensity statins compared with placebo (4.8% vs. 3.5% annually)

Among patients with known diabetes at baseline, glycemia worsened slightly with statin therapy compared with placebo

Here is the problem- diabetes is a number—a surrogate if you will. Statins fix a surrogate but have been proven to improve patient orientated outcomes

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