Episode 309: 308. Mailed feedback to Primary Care Physicians on Antibiotic Prescribing

Episode 309: 308. Mailed feedback to Primary Care Physicians on Antibiotic Prescribing

https://www.bmj.com/content/385/bmj-2024-079329



Overprescription of antibiotics by primary care clinicians is a major modifiable driver of antibiotic resistance. Evidence suggests that peer-comparison feedback can reduce antibiotic overprescription, but the optimal content and delivery of such feedback is unclear

Researchers randomized 5000 family physicians in Ontario, Canada, to receive either mailed feedback (with data on individual prescribing rates compared with peers' prescribing rates, plus educational information on optimal prescribing) or no mailed feedback (control group).

Clinicians in the intervention group were randomized further to (a) receiving personalized prescribing data that were adjusted, versus not adjusted, for case mix, and (b) receiving information on potential harms of antibiotics, versus not receiving such information.


Compared with controls, the intervention group had significantly lower mean rates of overall antibiotic prescribing (59 vs. 56 prescriptions per 1000 patient visits; relative rate, 0.95), apparently unnecessary antibiotic prescriptions (e.g., for viral illnesses; RR, 0.89), long-duration antibiotic prescriptions (RR, 0.85), and broad-spectrum antibiotic prescriptions (RR, 0.94) in the first 6 months after the mailings.

Only 18% of a sample of intervention physicians confirmed receipt of feedback letters.

Tells me—there has to be a personal connection. If you think this is you then you are likely to be make a change but with only 18% people confirming receipt is tells me

Physicians are burnt out—I refuse to believe they don’t care but rather they are drowning





Avsnitt(386)

Episode 376: 387. Methods Monday and an Example of Subgroup Analysis

Episode 376: 387. Methods Monday and an Example of Subgroup Analysis

https://www.nejm.org/doi/full/10.1056/NEJMoa2405923?query=clinical-medicine Mineralocorticoid receptor antagonists have been shown to reduce mortality in patients after myocardial infarction with cong...

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Episode 375: 386. Could half dose anticoagulation be the answer?

Episode 375: 386. Could half dose anticoagulation be the answer?

Estimated 5-year incidence of recurrent VTE was similar in the reduced-dose and full-dose groups (2.2% and 1.8%). Estimated 5-year bleeding incidence was significantly lower with reduced-dose than wi...

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Episode 374: 385. PRACTICE CHANGER! Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis

Episode 374: 385. PRACTICE CHANGER! Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis

https://www.nejm.org/doi/full/10.1056/NEJMoa2405404NNT of 4! systemic metronid and topical clinda bid for one week

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Episode 373: 384. Chronic Kidney Disease and Empagliflozin Legacy Effect

Episode 373: 384. Chronic Kidney Disease and Empagliflozin Legacy Effect

What Was Studied?The EMPA-KIDNEY trial followed 6,609 CKD patients at risk of disease progression. Participants were randomly assigned to receive empagliflozin (10 mg daily) or a placebo for a median ...

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Episode 372: 383. What is the GFR at which we stop metforin?

Episode 372: 383. What is the GFR at which we stop metforin?

Metformin while not necessarily first line therapy for diabetes depending on the patients co-morbid conditions it is certainly highly ranked on the list of medications! I know often metformin is stopp...

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Episode 371: 382. Is it safe to give the flu and covid vaccine at the same time?

Episode 371: 382. Is it safe to give the flu and covid vaccine at the same time?

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2825813Conclusions and Relevance  In this randomized clinical trial assessing simultaneous vs sequential administration of mRNA COVID-19 an...

4 Mars 20257min

Episode 370: 381. Relative efficacy of prehabilitation interventions and their components

Episode 370: 381. Relative efficacy of prehabilitation interventions and their components

https://www.bmj.com/content/388/bmj-2024-081164systematic review and meta-analysis on prehabilitation before surgery, published in the BMJ in February 2025.Prehabilitation aims to prepare patients for...

27 Feb 20257min

Episode 369: 380. REPOST mammo part 2

Episode 369: 380. REPOST mammo part 2

Mammograms

24 Feb 202520min

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