Episode 310: 309. Hospital-Associated Venous Thromboembolism Prophylaxis Use by Risk Assessment

Episode 310: 309. Hospital-Associated Venous Thromboembolism Prophylaxis Use by Risk Assessment

https://shmpublications.onlinelibrary.wiley.com/doi/abs/10.1002/jhm.13350


Xu J et al. Hospital-associated venous thromboembolism prophylaxis use by risk assessment at a large integrated health care network in Northern California. J Hosp Med 2024 Jun; 19:449.



Authors took 850,000 adult nonsurgical, non–intensive care unit (ICU) hospitalizations at 21 Kaiser Permanente hospitals in northern California, and did a retrospective study of inpatient pharmacologic VTE prophylaxis, investigators compared risk assessment by admitting physicians with risk assessment according to electronic health record (EHR)-

The EHR used the Padua prediction score which basically ask yes or no questions like does the pt have active cancer, previous vte, reduce mobility, elderly age, heart or resp failure. All questions that could need a human to fill out but also with could AI or HER should be answered without humans doing anything.



In 82% of 850,000 adult nonsurgical, non–intensive care unit (ICU) hospitalizations, the EHR categorized patients as low risk (i.e., not meeting indications for pharmacologic VTE prophylaxis); however, 42% of such patients (≈300,000 patients) received pharmacologic VTE prophylaxis. Among the 18% of hospitalizations where Padua score assessments indicated high risk (i.e., met indications for pharmacologic VTE prophylaxis), only one third received pharmacologic VTE prophylaxis.

There was years of making sure people give VTE but maybe we have went to far but the only way to solve this problem is give doctors fewer patient and more time or make it incorporated into the HER automatically. Make it idiot proof.

Hospitals should begin to incorporate better validated tools within EHRs to guide clinical decision-making for inpatient VTE prophylaxis. But even without such tools, clinicians should be vigilant in applying pharmacologic VTE prophylaxis in high-risk patients and minimizing its use in patients at low risk.

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Episode 376: 387. Methods Monday and an Example of Subgroup Analysis

Episode 376: 387. Methods Monday and an Example of Subgroup Analysis

https://www.nejm.org/doi/full/10.1056/NEJMoa2405923?query=clinical-medicine Mineralocorticoid receptor antagonists have been shown to reduce mortality in patients after myocardial infarction with cong...

17 Mars 20258min

Episode 375: 386. Could half dose anticoagulation be the answer?

Episode 375: 386. Could half dose anticoagulation be the answer?

Estimated 5-year incidence of recurrent VTE was similar in the reduced-dose and full-dose groups (2.2% and 1.8%). Estimated 5-year bleeding incidence was significantly lower with reduced-dose than wi...

14 Mars 20258min

Episode 374: 385. PRACTICE CHANGER! Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis

Episode 374: 385. PRACTICE CHANGER! Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis

https://www.nejm.org/doi/full/10.1056/NEJMoa2405404NNT of 4! systemic metronid and topical clinda bid for one week

12 Mars 20256min

Episode 373: 384. Chronic Kidney Disease and Empagliflozin Legacy Effect

Episode 373: 384. Chronic Kidney Disease and Empagliflozin Legacy Effect

What Was Studied?The EMPA-KIDNEY trial followed 6,609 CKD patients at risk of disease progression. Participants were randomly assigned to receive empagliflozin (10 mg daily) or a placebo for a median ...

11 Mars 20259min

Episode 372: 383. What is the GFR at which we stop metforin?

Episode 372: 383. What is the GFR at which we stop metforin?

Metformin while not necessarily first line therapy for diabetes depending on the patients co-morbid conditions it is certainly highly ranked on the list of medications! I know often metformin is stopp...

6 Mars 202510min

Episode 371: 382. Is it safe to give the flu and covid vaccine at the same time?

Episode 371: 382. Is it safe to give the flu and covid vaccine at the same time?

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2825813Conclusions and Relevance  In this randomized clinical trial assessing simultaneous vs sequential administration of mRNA COVID-19 an...

4 Mars 20257min

Episode 370: 381. Relative efficacy of prehabilitation interventions and their components

Episode 370: 381. Relative efficacy of prehabilitation interventions and their components

https://www.bmj.com/content/388/bmj-2024-081164systematic review and meta-analysis on prehabilitation before surgery, published in the BMJ in February 2025.Prehabilitation aims to prepare patients for...

27 Feb 20257min

Episode 369: 380. REPOST mammo part 2

Episode 369: 380. REPOST mammo part 2

Mammograms

24 Feb 202520min

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