JGO Weekly Summary (October 8, 2024)

JGO Weekly Summary (October 8, 2024)

In this episode of the Journal of Gynecologic Oncology podcast, we delve into a study examining the prognostic significance of HER2 expression in uterine carcinosarcoma (UCS), a rare and aggressive endometrial cancer. Conducted by Mizoguchi et al., the research analyzes HER2 status in 148 UCS patients using immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) testing. The findings reveal that in early-stage UCS, HER2-negative or low expression is associated with poorer overall survival compared to high HER2 expression, indicating that HER2 IHC scoring could be a valuable prognostic marker in early-stage disease. However, in advanced stages, HER2 status does not correlate with survival outcomes. The study underscores the potential of HER2-targeted therapies, particularly in early-stage UCS, and suggests that IHC alone may be sufficient for UCS prognostication. Tune in to explore the implications of these findings for future treatment strategies.

HER2-negative or low expression as an unfavorable prognostic factor in patients with stage I/II uterine carcinosarcoma (https://doi.org/10.3802/jgo.2025.36.e14)

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(37)

JGO Weekly Summary (July 6, 2025)

JGO Weekly Summary (July 6, 2025)

This episode summarizes a cross-sectional study from Central China on HPV genotype distribution and infection risk factors. Ye Chen and colleagues found that HPV52, 16, and 58 were most common, with i...

6 Juli 20254min

JGO Weekly Summary (May 11, 2025)

JGO Weekly Summary (May 11, 2025)

In this episode of the JGO Podcast, we explore a recent study from Peking Union Medical College Hospital examining the role of adjuvant surgery in patients with high-risk chemorefractory or relapsed g...

11 Maj 20254min

JGO Weekly Summary (April 29, 2025)

JGO Weekly Summary (April 29, 2025)

This episode features an in-depth discussion of the Asian cohort analysis from the AtTEnd/ENGOT-EN7 phase III trial, which evaluated atezolizumab in combination with carboplatin and paclitaxel for adv...

1 Maj 20255min

JGO Weekly Summary (April 22, 2025)

JGO Weekly Summary (April 22, 2025)

In this episode, we review findings from the Japan subset of the DUO-E phase III trial, led by Shin Nishio and colleagues, which evaluated durvalumab with or without olaparib following chemotherapy in...

22 Apr 20254min

JGO Weekly Summary (April 10, 2025)

JGO Weekly Summary (April 10, 2025)

In this episode, we discuss the final analysis of the KEYNOTE-826 subgroup study led by Dr. Yong-Man Kim, evaluating pembrolizumab plus chemotherapy with or without bevacizumab in East Asian patients ...

10 Apr 20255min

JGO Weekly Summary (March 25, 2025)

JGO Weekly Summary (March 25, 2025)

In this episode of the Journal of Gynecologic Oncology podcast, we review a recent meta-analysis by Tianyu Zhang and colleagues titled "Role of Adjuvant Chemotherapy in Stage IC Ovarian Granulosa Cell...

26 Mars 20255min

JGO Weekly Summary (March 18, 2025)

JGO Weekly Summary (March 18, 2025)

In this episode of the Journal of Gynecologic Oncology podcast, we discuss a study by Baldwin and colleagues titled Evaluation of the Role of Liver Metastasectomy in the Treatment of Stage IV Endometr...

19 Mars 20254min

JGO Weekly Summary (March 11, 2025)

JGO Weekly Summary (March 11, 2025)

This episode explores a recent study on the increased risk of cardiovascular disease among adolescent and young adult survivors of cervical cancer. Using data from the Korean National Health Insurance...

11 Mars 20255min

Populärt inom Hälsa

somna-med-henrik
rss-jossan-nina
rss-bara-en-till-om-beroende-medberoende
bullfika
inga-beiga-morsor
rss-vuxna-pa-latsas
not-fanny-anymore
rss-viktmedicinpodden
angestpodden
sexnoveller-deluxe
johannes-hansen-podcast
rss-hos-psykologen
sa-in-i-sjalen
sova-med-dan-horning
rss-basta-livet
tyngre-traningssnack
halsoveckan-by-tyngre
brottarbroder
rss-angra-inget-3
rss-angra-inget-2