Who visits raccoon latrines, and boosting cancer therapy with gut microbes

Who visits raccoon latrines, and boosting cancer therapy with gut microbes

David Grimm—online news editor for Science—talks with Sarah Crespi about a long-term project monitoring raccoon latrines in California. What influence do these wild bathrooms have on the ecosystem? Sarah also interviews Christian Jobin of the University of Florida in Gainesville about his Perspective on three papers linking the success of cancer immunotherapy with microbes in the gut—it turns out which bacteria live in a cancer patient’s intestines can predict their response to this cutting-edge cancer treatment. Read the related papers: Routy et al., Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors, Science 2018 Gopalakrishnan et al., Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients, Science 2018 Matson et al., The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients, Science 2018 aan4236 Listen to previous podcasts. [Image: cuatrok77/Flickr; Music: Jeffrey Cook] Learn more about your ad choices. Visit megaphone.fm/adchoices

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Avsnitt(642)

Fighting deepfakes, and using bacteria to deliver medicine inside the body

Fighting deepfakes, and using bacteria to deliver medicine inside the body

First up on the podcast, Meagan Cantwell produced a segment with Contributing Correspondent Kai Kupferschmidt on the fight against deepfakes. Kupferschmidt talks with Hany Farid, professor at the Univ...

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A team effort to save a giant fish, the power of moonlight, and how scientists can navigate a tough political environment

A team effort to save a giant fish, the power of moonlight, and how scientists can navigate a tough political environment

First up on the podcast, along Brazil’s Juruá River, local residents have been working with scientists to manage a giant fish called the arapaima—affecting the land, the people, and the economy. Contr...

7 Maj 53min

Watching a spiders’ heart beat, epigenetic ethics, and what science biographies reveal about fame

Watching a spiders’ heart beat, epigenetic ethics, and what science biographies reveal about fame

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Cleaning up uranium mining, and how the heart avoids cancer

Cleaning up uranium mining, and how the heart avoids cancer

First up on the podcast, freelance science and environmental journalist Quentin Septer joins host Sarah Crespi to talk about a controversial uranium mine getting fast-tracked in South Dakota. Septer c...

23 Apr 30min

The normals | Episode 3

The normals | Episode 3

The final of a three-part limited Science Podcast series that looks at the history of normal human subjects in research In episode two, we heard what happened to the normals program after church volu...

21 Apr 33min

How to keep quantum computers cool, whether prediction markets harm public health, and podcasting on podcasting

How to keep quantum computers cool, whether prediction markets harm public health, and podcasting on podcasting

First up on the podcast, quantum computers require extremely low temperatures—less than 1°C away from absolute zero. But getting down to those temperatures has usually required dilution fridges using ...

16 Apr 50min

The Normals | Episode 2

The Normals | Episode 2

Last time on The Normals, we learned that in the 1950s, the National Institutes of Health (NIH) wanted to recruit many healthy volunteers for basic research. Two peace churches, the Mennonites and the...

14 Apr 27min

A chimpanzee ‘civil war,’ and NASA plans for nuclear propulsion

A chimpanzee ‘civil war,’ and NASA plans for nuclear propulsion

First up on the podcast, freelance science journalist Hannah Richter joins host Sarah Crespi to discuss NASA’s plans to send a nuclear-powered spacecraft to Mars in less than 3 years. Having not launc...

9 Apr 42min

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