Science’s leading role in the restoration of Notre Dame and the surprising biology behind how our body develops its tough skin

Science’s leading role in the restoration of Notre Dame and the surprising biology behind how our body develops its tough skin

On this week’s show, freelance writer Christa Lesté-Lasserre talks with host Sarah Crespi about the scientists working on the restoration of Notre Dame, from testing the changing weight of wet limestone, to how to remove lead contamination from four-story stained glass windows. As the emergency phase of work winds down, scientists are also starting to use the lull in tourist activity to investigate the mysteries of the cathedral’s construction. Also this week, Felipe Quiroz, an assistant professor in the biomedical engineering department at the Georgia Institute of Technology and Emory University, talks with Sarah about his paper on the cellular mechanism of liquid-liquid phase separation in the formation of the tough outer layer of the skin. Liquid-liquid phase separation is when two liquids “demix,” or separate, like oil and water. In cells, this process created membraneless organelles that are just now starting to be understood. In this work, Quiroz and colleagues create a sensor for phase separation in the cell that works in living tissue, and show how phase separation is tied to the formation of the outer layers of skin in mice. Read the related Insight. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: r. nial bradshaw/Flickr; Music: Jeffrey Cook] Authors: Sarah Crespi; Christa Lesté-Lasserre Learn more about your ad choices. Visit megaphone.fm/adchoices

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Building better working dogs, and watching a black hole form

Building better working dogs, and watching a black hole form

First up on the podcast, more than half of all dogs going through service animal training don’t make it to graduation. Producer Kevin McLean journeys with Online News Editor David Grimm to Canine Comp...

12 Feb 34min

Engineering safer football helmets, and the science behind drug overdoses

Engineering safer football helmets, and the science behind drug overdoses

First up on the podcast, host Sarah Crespi and Staff Writer Adrian Cho talk football and the latest science behind helmets engineered to reduce head injuries. Have better materials and testing led to ...

5 Feb 39min

Shielding astronauts from cosmic rays, and planning the end of fossil fuels

Shielding astronauts from cosmic rays, and planning the end of fossil fuels

First up on the podcast, how do we protect astronauts when they leave the shelter of Earth’s protective magnetic fields and face the slow, constant bombardment of space radiation? Freelance science jo...

29 Jan 38min

Tracking falling space debris via sonic booms, and getting drunk off your own microbes

Tracking falling space debris via sonic booms, and getting drunk off your own microbes

First up with Jennie Erin Smith, Science’s new senior biomedicine reporter, we delve into: autobrewery syndrome, when microbes inside the human gut make too much alcohol; how doctors can use a public ...

22 Jan 32min

Reversing ecological destruction in the Galápagos, and finally mapping Antarctica’s surface

Reversing ecological destruction in the Galápagos, and finally mapping Antarctica’s surface

First up on the podcast, freelance science journalist Sofia Quaglia talks about her visit to the Galápagos archipelago and how researchers there are working to restore the islands to their former ecol...

15 Jan 30min

The real da Vinci code, and the world’s oldest poison arrows

The real da Vinci code, and the world’s oldest poison arrows

First up on the podcast, scholars are on a quest to find Leonardo da Vinci’s DNA. With no direct descendants, the hunt involves sampling the famous polymath’s papers, paintings, and distant cousins. C...

8 Jan 27min

Looking for continents on exoplanets, and math is hard for mathematicians, too

Looking for continents on exoplanets, and math is hard for mathematicians, too

First up on the podcast, the best images of exoplanets right now are basically bright dots. We can’t see possible continents, potential oceans, or even varying colors. To improve our view, scientists ...

1 Jan 43min

This year’s biggest breakthrough and top news stories

This year’s biggest breakthrough and top news stories

First up on the podcast, Online News Editor David Grimm joins host Sarah Crespi to talk about this year’s best online news stories—top performers and staff picks alike. Together they journey the scien...

18 Dec 202533min

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