DOGE vs USAID, Crypto Framework, Google's $75B AI Spend, US Sovereign Wealth Fund, GLP-1s

Show Notes: 0:00 Intro & Dog update 5:48 COVID, Vaccine mandates, public vs. private policy 26:26 Collectivism, comparison to cigarettes, Sacks' latest podcast beef 36:56 Vaccine incentives in France 45:39 Friedberg's science corner: DeepMind's latest breakthrough, Big Tech censorship, free speech infringements 59:40 Capital's role in progress, Bezos' poor press conference, difference in criticism by party, Elon & Bezos as capital allocators 1:10:46 Modern online pessimist psychology & how to fix it 1:21:32 Besties give their tech industry takeaways Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Referenced in the show: NYT - In France, angry protests, rising infections and record vaccinations. https://www.nytimes.com/2021/07/19/world/france-covid-vaccine-pass-protests.html NYT - Military and V.A. Struggle With Vaccination Rates in Their Ranks https://www.nytimes.com/2021/07/01/us/politics/military-va-vaccines.html CNBC - Biden on Facebook: ‘They’re killing people’ with vaccine misinformation https://www.cnbc.com/2021/07/16/white-house-says-facebook-needs-to-do-more-to-fight-vaccine-misinformation.html Fortune - In giant leap for biology, DeepMind’s A.I. reveals secret building blocks of human life https://fortune.com/2021/07/22/deepmind-alphafold-human-proteome-database-proteins/ The Wizard of Menlo Park - Randall E. Stross https://www.amazon.com/Wizard-Menlo-Park-Thomas-Invented/dp/1400047633 Tweets: https://twitter.com/OliviaGoldhill/status/1417446281685966853 https://twitter.com/DavidSacks/status/1416879494283993088 https://twitter.com/ACLU/status/1417632367200673794

23 Juli 20211h 35min

Show Notes: 0:00 Bestie game show: Who got COVID? How was the experience? 9:30 Delta breakthrough causing concern, potential new approaches, vaccine mandates 24:26 Implications on the economy, will people self-isolate even without government shutdowns? 40:09 Billionaire Space Race: Addressing the negativity, benefits of innovators 47:29 Investments in space, parallels to 1500's maritime shipping, potential for global broadband 1:04:07 Besties go to space, Bezos' cheap shot, Elon's support, Melvin Capital's tough first half of 2021 Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: WSJ Opinion - What Drives GOP Resistance to Vaccines? https://www.wsj.com/articles/what-drives-gop-resistance-to-vaccines-11623190392 NYT - Some Republican Leaders Speak Up for Vaccines https://www.nytimes.com/live/2021/07/14/world/covid-variant-vaccine-updates Reuters - Living with COVID-19: Israel changes strategy as Delta variant hits https://www.reuters.com/world/middle-east/living-with-covid-19-israel-changes-strategy-delta-variant-hits-2021-07-13/ Study Finds - Over 200 COVID ‘long hauler’ symptoms identified, many lasting longer than 6 months https://www.studyfinds.org/200-covid-long-hauler-symptoms/ CNN Opinion - Richard Branson's disappointing space jaunt https://www.cnn.com/2021/07/12/opinions/richard-branson-jeff-bezos-space-flight-is-a-waste-thomas/index.html Truth Out Op-ed - Billionaire Tax Cheat Travels to Space for a Few Minutes https://truthout.org/articles/billionaire-tax-cheat-travels-to-space-for-a-few-minutes Fox News - Richard Branson says critics are 'not fully educated' on benefits of space travel https://www.foxnews.com/media/richard-branson-critics-not-fully-educated-space-travel CNBC - Investment in space companies put at record $8.9 billion in 2020 despite Covid https://www.cnbc.com/2021/01/25/investing-in-space-companies-hits-record-8point9-billion-in-2020-report.html Bloomberg - Melvin Struggles to Shake Reddit Attack With 46% Loss So Far https://www.bloomberg.com/news/articles/2021-07-08/melvin-can-t-shake-reddit-attack-with-46-loss-in-first-half Books: Andy Weir - Project Hail Mary https://www.amazon.com/Project-Hail-Mary-Andy-Weir/dp/0593135202 Jeremy England - Every Life Is on Fire https://www.amazon.com/Every-Life-Fire-Thermodynamics-Explains/dp/1541699017 Tweets: https://twitter.com/ScottAdamsSays/status/1415287991954640901 https://twitter.com/micsolana/status/1415122089720254467 https://twitter.com/elonmusk/status/1414157827145404419 https://twitter.com/blueorigin/status/1413521627116032001 https://twitter.com/elonmusk/status/1386825367948644352

16 Juli 20211h 18min

Show Notes: 0:00 Super drought & climate crisis on the west coast 25:53 Nuclear energy, virtue signaling, cognitive laziness, positive signals of optimism 36:50 Friedberg's "anti-science" theory 44:48 San Francisco chaos, "crime is down" controversy, viral crime videos 59:42 Are Israel's recent COVID vaccine findings problematic? Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: Nuclear energy timeline https://drive.google.com/file/d/1GSIb-vyIvZalcE9LCBFqbQjsvE4uu-c-/view?usp=sharing The Grid: The Fraying Wires Between Americans and Our Energy Future https://www.amazon.com/Grid-Fraying-Between-Americans-Energy-ebook/dp/B01DM9Q6CQ MarketWatch - Target shortens hours in San Francisco due to ‘alarming rise’ in shoplifting https://www.marketwatch.com/story/target-shortens-hours-in-san-francisco-due-to-alarming-rise-in-shoplifting-11625688560 Israel Ministry of Health - Decline in Vaccine Effectiveness Against Infection and Symptomatic Illness https://www.gov.il/en/departments/news/05072021-03 Tweets: https://twitter.com/friedberg/status/1413044148735672322 https://twitter.com/michelletandler/status/1411362359734542343 https://twitter.com/michelletandler/status/1411943649231851522 https://twitter.com/cyantist/status/1412478525014085632 https://twitter.com/briansugar/status/1412507632267534340 https://twitter.com/activeasian/status/1412252070829182976 https://twitter.com/DavidSacks/status/1412160046046203909 https://twitter.com/DavidSacks/status/1412163715676327950 https://twitter.com/ThomasSowell/status/1412858750747217922 https://twitter.com/robkhenderson/status/1412899033933307911 https://twitter.com/sfchronicle/status/1409170317826793474 https://twitter.com/briansugar/status/1412507632267534340

9 Juli 20211h 10min

Show Notes: 0:00 Jason & Sacks hash out their Twitter beef 20:58 Robinhood $70M FINRA fine signals & S-1 news, plus how GPs think about IPO distributions 35:29 Delta variant: reason for concern or fear porn? 57:25 Trump not taking credit for Project Lightspeed, Trump CFO indicted, will Dems prosecuting Trump backfire & help him gain steam for 2024? 1:06:11 Future of Republican & Democratic parties 1:11:17 FTC takes a hit in Facebook case dismissal & Amazon requesting Lina Khan's recusal, does Facebook have the best case against being a monopoly? 1:19:42 Sha'Carri Richardson Olympic suspension Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Referenced in the show: All-In Stats - E37 https://newsletter.allinstats.com/issues/all-in-stats-episode-37-662814 FINRA fines Robinhood $70M https://www.finra.org/media-center/newsreleases/2021/finra-orders-record-financial-penalties-against-robinhood-financial Robinhood S-1 https://www.sec.gov/Archives/edgar/data/1783879/000162828021013318/robinhoods-1.htm CNN - The Delta variant will cause 'very dense outbreaks' in these five states, expert says https://www.cnn.com/2021/06/28/health/us-coronavirus-monday/index.html Google - US vaccine rates by state https://www.google.com/search?q=vaccination+rates+by+state&oq=vaccination+rates+by&aqs=chrome.0.0i131i433j0i433j69i57j0i131i433j0i433j0i395i433j0i395i457j69i61.3260j1j7&sourceid=chrome&ie=UTF-8 Experimental Assessment of Carbon Dioxide Content in Inhaled Air With or Without Face Masks in Healthy Children https://jamanetwork.com/journals/jamapediatrics/fullarticle/2781743 Politico - ‘Not a healthy environment’: Kamala Harris’ office rife with dissent https://www.politico.com/news/2021/06/30/kamala-harris-office-dissent-497290 Politico - DeSantis ‘very wary’ of upsetting Trump https://www.politico.com/news/2021/06/28/desantis-trump-gop-election-496367 CNBC - Judge dismisses FTC and state antitrust complaints against Facebook https://www.cnbc.com/2021/06/28/judge-dismisses-ftc-antitrust-complaint-against-facebook.html Amazon's petition for Lina Khan recusal https://s.wsj.net/public/resources/documents/AMZN%20petition%20re%20Khan.pdf NYT - Sha’Carri Richardson, a Track Sensation, Tests Positive for Marijuana https://www.nytimes.com/2021/07/01/sports/olympics/shacarri-richardson-suspended-marijuana.html Tweets: https://twitter.com/ALLIN_STATS/status/1409269704573820939 https://twitter.com/DavidSacks/status/1409282278270849028 https://twitter.com/Jason/status/1409282966354857986 https://twitter.com/DavidSacks/status/1409287404628938753 https://twitter.com/DavidSacks/status/1409554101713702917 https://twitter.com/Jason/status/1409289443161382912 https://twitter.com/trvrb https://twitter.com/trvrb/status/1410432407816212481 https://twitter.com/maggieNYT/status/1410682821358858242 https://twitter.com/SenWarren/status/1409649814308986888 https://twitter.com/DavidSacks/status/1409723626476216321

3 Juli 20211h 26min

Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Referenced in the show: NYT - N.Y.C. Mayoral Race Highlights: Adams Leads in Early Results Over Wiley and Garcia https://www.nytimes.com/live/2021/06/22/nyregion/nyc-primary-election Vanity Fair - Eric Adams interview https://www.vanityfair.com/news/2021/06/eric-adams-nyc-mayor-interview NY Daily News - ‘We don’t want fancy candidates’: Eric Adams declares himself ‘face of the new Democratic Party’ https://www.nydailynews.com/news/politics/nyc-elections-2021/ny-eric-adams-democratic-party-nyc-mayoral-race-20210624-oemlj42abzc7jnime4tjfddfhm-story.html Jesse Bloom COVID origin research paper https://www.biorxiv.org/content/10.1101/2021.06.18.449051v1 Destined for War: Can America and China Escape Thucydides’s Trap? by Graham Allison https://rb.gy/7vj8ks Apple says third-party app stores would leave iPhone users vulnerable to scammers https://fortune.com/2021/06/23/apple-iphone-third-party-app-store-users The Pull Request - Bad Apple* by Antonio Garcia Martinez https://www.thepullrequest.com/p/bad-apple Show Notes: 0:00 Besties hash out a new format & the purpose of the podcast 14:31 NYC rejects far-left candidates in mayoral primary; importance of crime, homelessness & drug abuse in elections 29:29 New developments in the Wuhan lab leak theory, ramifications for our relationship with China 54:07 Congress turns the heat on up big tech, Apple's App Store monopoly in trouble 1:09:25 Antonio Garcia Martinez's first Substack article on Apple

25 Juni 20211h 19min

Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Show Notes: 00:00 Besties intro 03:37 Lina Khan appointed to the Chair of the Federal Trade Commission 07:02 Will Lina break up big tech? Which one will be first? 18:02 Potential repercussions to consumers 27:48 Sacks’ antitrust experience at PayPal vs. Ebay, Visa & MasterCard 29:50 Google’s multi-trillion dollar data trove 35:40 The U.S. government's capability to silently take data while “gagging” Big Tech 53:32 COVID’s psychic shadow, Friedberg’s office landlord is still requiring masks 1:00:17 Jon Stewart’s lab leak bit on Stephen Colbert’s show 1:10:04 California’s wildfire risk increasing with climate change 1:20:57 Besties summer plans Referenced in the show: Chamath's 2019 Annual Letter re: Big Tech breakup https://www.socialcapital.com/annual-letters/2019 Big Tech Gag Order (mentioned by Sacks) https://www.washingtonpost.com/opinions/2021/06/13/microsoft-brad-smith-trump-justice-department-gag-orders/ Obama Administration Record Seizure (mentioned by Sacks) https://www.nytimes.com/2013/05/14/us/phone-records-of-journalists-of-the-associated-press-seized-by-us.html?referringSource=articleShare California Forest fire maps (mentioned by Friedberg) https://twitter.com/NWSBayArea/status/1398474379214802951/photo/1 Jon Stewart On Vaccine Science And The Wuhan Lab Theory https://www.youtube.com/watch?v=sSfejgwbDQ8 #allin #tech #news

18 Juni 20211h 27min

Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Show Notes: 0:00 Bestie intro, Chamath's whereabouts 2:54 Breaking down Biogen's Alzheimer's drug & the FDA's controversial approval 26:46 Billionaire space race: Is Bezos going to space too risky or a smart marketing move? How the space industry is a perfect example of effective government intervention. Can anyone dominate space? 42:55 Big Tech getting back to the office: what is the new normal for companies with thousands of employees? 56:49 Recent factors on the commercial & private real estate markets, inflation head fake 1:05:01 ProPublica's report on billionaire tax returns 1:15:58 Bitcoin toxicity, Snowflake's CEO apologizes for comments on merit & diversity 1:32:48 Science corner with Friedberg: Induced pluripotent stem cells & cloning Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Referenced in the show: https://www.statnews.com/2021/06/07/fda-grants-historicapproval-to-alzheimers-drug-designed-to-slow-cognitive-decline/ https://www.bloomberg.com/news/articles/2021-06-10/harvard-expert-quits-fda-panel-as-furor-over-biogen-drug-grows https://www.instagram.com/p/CP0MSOqnYEo https://www.wsj.com/articles/facebook-lets-more-employees-choose-full-time-remote-work-or-return-to-the-office-11623258049 https://news.yahoo.com/salesforce-ceo-marc-benioff-on-slack-acquisition-135151402.html https://socketsite.com/archives/2021/04/visualizing-all-the-vacant-office-space-in-san-francisco.html https://www.wsj.com/articles/if-you-sell-a-house-these-days-the-buyer-might-be-a-pension-fund-11617544801 https://fred.stlouisfed.org/series/T10YIE https://www.propublica.org/article/the-secret-irs-files-trove-of-never-before-seen-records-reveal-how-the-wealthiest-avoid-income-tax https://www.aqr.com/Insights/Research/Journal-Article/Buffetts-Alpha https://www.ft.com/content/42daca9e-facc-11e7-9bfc-052cbba03425 https://www.bloomberg.com/news/articles/2021-06-07/snowflake-ceo-offers-apologies-support-for-hiring-diversity Tweets: https://twitter.com/Jason/status/1401938511826067457 https://twitter.com/elonmusk/status/1386825367948644352 https://twitter.com/micsolana/status/1403394491143315456 https://twitter.com/Jason/status/140302318070958080

13 Juni 20211h 35min

Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Referenced in the show: WSJ - The Wuhan Lab Leak Question: A Disused Chinese Mine Takes Center Stage https://www.wsj.com/articles/wuhan-lab-leak-question-chinese-mine-covid-pandemic-11621871125 Forbes - Friends Don't Let Friends Become Chinese Billionaires https://www.forbes.com/sites/raykwong/2011/07/25/friends-dont-let-friends-become-chinese-billionaires/?sh=44597352ddae Brookings - Fentanyl and geopolitics: Controlling opioid supply from China https://www.brookings.edu/research/fentanyl-and-geopolitics-controlling-opioid-supply-from-china/ NPR - 'We Are Shipping To The U.S.': Inside China's Online Synthetic Drug Networks https://www.npr.org/2020/11/17/916890880/we-are-shipping-to-the-u-s-china-s-fentanyl-sellers-find-new-routes-to-drug-user Coinbase - Announcing Coinbase Fact Check: Decentralizing truth in the age of misinformation https://blog.coinbase.com/announcing-coinbase-fact-check-decentralizing-truth-in-the-age-of-misinformation-757d2392d61a Show Notes: 0:00 Friedberg recaps Sacks' birthday party 6:47 "Wuhan Lab Leak" theory, did COVID come from a lab? Plusn China's fentanyl production 26:09 India's new "traceability" law 33:11 Coinbase & Brian Armstrong debut fact checking blog 41:17 Friedberg's science corner: groundbreaking gene therapies 45:06 Amazon's MGM acquisition, media consolidation 1:04:45 Biden's $6T infrastructure, Democrat's feeling the inflation pressure & responding

31 Maj 20211h 8min