Dementia Matters9 Dec 2021

New Research Shifts Thinking on Metabolism and Aging

There are many common beliefs about metabolism. Perhaps you’ve heard that a person’s metabolism slows around middle age, or that a woman’s metabolism is slower than a man’s. However widespread these beliefs are, recent research from the journal Science has found that these conceptions of metabolism are wrong. In a groundbreaking study, researchers have found that metabolism goes through four key phases over our lives, only beginning to slow around age 60. This, among other findings, are now changing how we think about human physiology and how we think about aging. Breaking down this new research and his perspective article on the findings, Dr. Rhoads describes our shifting understandings of metabolism and how it impacts chronic diseases like Alzheimer’s disease as we age.

Guest: Tim Rhoads, PhD, assistant scientist, Rozalyn Anderson laboratory, University of Wisconsin School of Medicine and Public Health

Episode Topics

2:30 - How is metabolism related to diseases of aging?

4:42 - What are the four distinct phases of metabolism and why are they important?

7:44 - What are other findings that change our understanding of metabolism?

12:00 - How does the decline in metabolism later in life affect chronic diseases like Alzheimer’s disease? Are there things we could do to prolong a high metabolism?

15:22 - How does caloric restriction affect the body and metabolism?

Show Notes

Read the perspective piece written by Dr. Rhoads and Dr. Rozalyn Anderson on the journal Science’s website.

Read the original research report, “Daily energy expenditure through the human life course,” by Pontzer et al. on the journal Science’s website.

Learn more about recent metabolism research in the article, “What We Think We Know About Metabolism May Be Wrong,” written for the New York Times.

Learn more about the Rozalyn Anderson Lab and their research at their website.

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(242)

How Dementia Caregiving Affects the Spousal Caregiver

Caring for those with dementia represents a major public health challenge, with caregivers, especially spouses, providing long-term, largely unpaid care. With caregiving stress linked to a decline in ...

28 Juli 39min

Managing the Medicine Cabinet: How Prescriptions Impact Cognition and Brain Health as We Age

Prescription medications, over-the-counter drugs and supplements are incredibly common among older adults, yet many of these routine treatments can unexpectedly impact cognitive function and brain hea...

14 Juli 35min

Taking a Deep Dive into Subjective Cognitive Decline

Dr. Jessen returns to the podcast to take a deeper dive into subjective cognitive decline (SCD). Aiming to cover everything relating to SCD, Dr. Jessen shares insights in prognosis, risk factors and h...

7 Juli 17min

Defining Subjective Cognitive Decline

Subjective cognitive decline (SCD) can be one of the earliest noticeable signs of Alzheimer's disease, yet SCD is not yet fully understood. To help us understand more, Dr. Frank Jessen, an expert in t...

30 Juni 30min

SPRINT to a Healthy Mind: How Blood Pressure Control Affects Brain Health and Dementia Risk

Geriatrician Dr. Mark Supiano joins the podcast to discuss the connection between heart and brain health. Citing multiple clinical trials, he breaks down what these studies and their findings mean for...

18 Juni 40min

Addressing Cochrane’s Review on Amyloid-Targeting Treatments for Alzheimer’s Disease

Amyloid-targeting monoclonal antibody treatments have ushered in a new era of Alzheimer’s disease therapies after decades of research and clinical trials. A recent review published by Cochrane, a glob...

4 Juni 44min

What to Expect from ‘When Memory Fades’ with Drs. Art Walaszek and Nathaniel Chin

Guest host Dr. Art Walaszek takes over the podcast to interview Dr. Chin about his upcoming book, When Memory Fades. In addition to discussing the importance of dementia research and other clinical to...

19 Maj 32min

New Study Examines the Effects of Food Insecurity on Dementia Risk

The latest Household Food Security report estimated that 13.7% of U.S. households experienced food insecurity in 2024. This lack of access to a nutritious diet can significantly affect health, so how ...

5 Maj 26min