The 10-Second At-Home Walk Test for Longevity (Easy Biohack) : 1317
Walking speed predicts your risk of death better than cholesterol—and this episode reveals why. You’ll learn how to test your biological age at home in just 10 seconds, and how to use that information to upgrade your human performance, extend your longevity, and tailor your biohacking strategy for maximum results. Discover the overlooked role of pelvic floor strength, glute activation, and neuromuscular training in brain optimization, metabolism, and injury prevention. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey speaks with Dr. Vonda Wright, a double board-certified orthopedic surgeon, hormone optimization expert, and elite sports medicine pioneer who’s worked with Olympic athletes, military special forces, and high-performing women through every phase of life. With decades of experience in functional medicine, movement science, and hormone therapy, Dr. Wright shares the essential strategies to prevent frailty, rebuild strength, and thrive through perimenopause and beyond. You’ll learn: • How walking speed reveals aging and longevity better than traditional blood tests • The biomechanics behind muscle “shutdown” and how to turn muscles back on • The truth about C-sections, pelvic floor rehab, and functional motion assessments • Which supplements, nootropics, and hormone therapies restore metabolism and vitality • Why perimenopause is a turning point for brain, bone, and cardiovascular health • Testing tools and training methods to upgrade strength, prevent falls, and age powerfully Whether you want to feel stronger, think sharper, or stay youthful into your 90s, this is your roadmap for smarter not harder biohacking with real-world impact. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: 10-second walk test longevity, pelvic floor dysfunction and aging, glute activation for brain health, perimenopause hormone replacement therapy, VO2 max biohacking, estrogen for bone density, neuromuscular reactivation exercises, functional movement assessment AI, post-C-section core recovery, velocity training for longevity, strength vs muscle mass aging, menopause testosterone therapy, mitochondrial health for women, sleep optimization progesterone, cold therapy for muscle recovery, fascia training for anti-aging, diastasis recti long-term effects, smart exercise hacks for aging, hormone optimization for libido and brain, smarter not harder fitness protocols Thank you to our sponsors! Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Resources: • Vonda's Website: https://www.drvondawright.com/ • Vonda's Instagram: https://www.instagram.com/drvondawright/?hl=en • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer1:23 — Intro2:55 — Muscle Atrophy and Reactivation6:10 — Pelvic Floor Health and Rehab8:47 — Joint Mobility and Movement10:02 — Science of Muscle Function18:23 — Perimenopause and Menolescence27:58 — Four Essential Female Hormones42:50 — VO2 Max and Longevity49:24 — Velocity Training and Bone Health62:30 — Turning Menopause into Power65:58 — Closing Thoughts and Book Rec See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
21 Aug 1h 7min
PhD at MIT: The Longevity Molecule That Reverses Aging (250 Studies) : 1316
Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade your mitochondria, and extend your healthspan. This episode gives you the real science, proven by over 250 studies, behind supplements, nutrition, and biohacking tools that actually work for brain optimization, metabolism, and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You’ll learn why NAD+ is a master regulator of mitochondrial health, how DNA methylation clocks accurately measure biological age, and why boosting sirtuin activity improves resilience, neuroplasticity, and recovery. Dr. Guarente shares insider strategies from decades of functional medicine research, including nootropics, targeted supplements, fasting protocols, and diet adjustments from carnivore to Mediterranean that can shift your metabolism toward longevity. Dave and Dr. Guarente explore advanced biohacks like cold therapy, sleep optimization, and ketosis, plus how to balance these interventions with your genetics, lifestyle, and health goals. You’ll also hear about the surprising role of homocysteine in brain aging, how to use lab testing to guide your longevity plan, and why resilience is the ultimate measure of health. You’ll learn: • How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk Whether you want to sharpen your brain, protect your heart, or upgrade your energy systems, this is a masterclass in smarter not harder biohacking for a longer, higher-performing life.Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: NAD+ supplementation, Sirtuin activation, DNA methylation clocks, Biological age testing, Mitochondrial biogenesis, Epigenetic reprogramming, Pterostilbene benefits, Nicotinamide riboside (NR), Nicotinamide mononucleotide (NMN), Homocysteine reduction, Oxidative stress repair, Superoxide dismutase (SOD) activation, Functional medicine longevity, Healthspan optimization, Resveratrol bioavailability, Menopause mitochondrial support, Phenylbutyrate and protein folding, High-fat diet longevity studies, Neurodegenerative disease biohacking, INCHIANTI aging study Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Elysium Website. Use code ‘UPGRADE25’ for 25% off the first month of a monthly subscription to any Elysium supplement: https://www.elysiumhealth.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction to NAD & Sirtuins 0:59 — Intro 7:04 — Animal vs Human Aging Studies 10:07 — Discovery of Sirtuins 14:43 — NAD’s Role in Aging 15:34 — Resveratrol vs Pterostilbene 23:13 — Timing NAD Supplementation 36:34 — Diet & Lifestyle Factors 50:05 — Elysium’s Basis & Signal 1:00:03 — Future Clinical Trials 1:05:14 — Psychology of Aging & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
19 Aug 1h 8min
Still Fasting in 2025? Here’s How to Make It Work Better : 1315
How do you activate your body’s natural repair system? How can you hack stem cells for faster recovery, brain optimization, and peak human performance? This episode reveals how to trigger stem cell release, direct them to the right tissues, and stack biohacking tools for maximum regeneration. You’ll learn science-backed strategies for boosting mitochondria, enhancing neuroplasticity, and extending longevity through targeted supplements, fasting, and functional medicine techniques. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Christian Drapeau, a leading stem cell scientist and founder of STEMREGEN. Christian’s decades of research have transformed our understanding of how stem cells repair the body, reverse damage, and amplify performance. He shares practical protocols to mobilize stem cells, improve microcirculation, and reduce inflammation so your body heals faster, functions better, and stays younger for longer. You’ll learn: • How stem cells rebuild muscle, brain, and organ tissue for optimal human performance • Why fasting rejuvenates bone marrow and increases stem cell effectiveness • The synergy between PEMF, vibration therapy, cold therapy, and stem cell activation • How microcirculation and inflammation control improve longevity and recovery • The best supplements and nutrients to support mitochondria and stem cell health • How to stack nootropics, ketosis, and brain optimization tools for lasting energy and focus This is essential listening for anyone serious about biohacking, longevity, human performance, mitochondria health, neuroplasticity, functional medicine, fasting protocols, supplements for recovery, brain optimization, smarter not harder healing, metabolism upgrades, cold therapy stacks, and next-level physical and cognitive resilience Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: STEMREGEN, biohacking, natural stem cell activation, human performance, longevity, mitochondria, neuroplasticity, fasting, bone marrow rejuvenation, functional medicine, supplements, brain optimization, metabolism, cold therapy, microcirculation, nootropics, ketosis, smarter not harder, recovery hacks Resources: • STEMREGEN Website: https://www.stemregen.co/dave for 20% off your first order. • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:00 — Why Some People Regenerate Better 1:52 — Testing Stem Cell Levels 2:58 — Natural Stem Cell Function 3:59 — Exercise & Stem Cell Response 5:13 — Tissue Turnover & Regeneration 7:03 — Bone Marrow Production 8:16 — Fasting & Bone Marrow 9:33 — Nutrition for Bone Marrow 11:14 — Traditional Meets Modern Science 12:58 — Training Bone Marrow 13:57 — Stem Cells as Repair System 34:20 — Stem Cells & Brain Injury 47:01 — Inside STEMREGEN Products 55:41 — Stress, Cortisol & Stem Cells 58:12 — Final Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
15 Aug 59min
How to Make Life-Changing Decisions Without Fear – Joe Hudson : 1314
How do you make tough decisions? How do you make them without fear or lying? This episode shows you how unresolved emotions disrupt decision-making, relationships, and functioning in peak brain performance. You’ll learn tips to rewire your nervous system for decision making, optimizing emotional intelligence, and regulating your body for high-level clarity, energy, and resilience. Discover biohacking techniques that use emotional release and somatic awareness to boost mitochondria, activate neuroplasticity, and achieve lasting personal transformation. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Joe Hudson, a world-renowned executive coach to unicorn founders and billion-dollar leaders. Joe works with a select group of top performers to unlock emotional clarity, leadership mastery, and deep personal change. His methods combine neuroscience, trauma healing, somatic therapy, and conscious coaching to help people perform at their highest level while becoming more authentic, fulfilled, and connected.You’ll learn:• How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk This is essential listening for anyone serious about emotional intelligence, high-performance coaching, biohacking, somatic healing, trauma work, executive leadership, nervous system regulation, brain optimization, functional medicine, and building unstoppable inner resilience. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Joe Hudson, Dave Asprey, emotional intelligence, nervous system regulation, somatic therapy, trauma healing, executive coaching, biohacking emotions, brain optimization, emotional mastery, making tough decisions, fear or failure, leadership development, negative self talk, childhood trauma, personal transformation, smarter not harder, stress relief tools, leadership listening Thank you to our sponsors! Puori | Head to http://puori.com/dave for 20% off, including subscriptions. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order. Resources: • Sign up for a complimentary transformation guide from Joe: https://www.artofaccomplishment.com/ • Joe’s Art of Accomplishment Podcast: https://open.spotify.com/show/6MjoHFfLmNgo0Msais7IJ2 • Daily Insights on Twitter: https://tinyurl.com/4kazb783 • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 2:42 — Why We Struggle with Fasting 6:28 — Identity and Control Patterns 11:56 — The Nervous System and Decision-Making 23:33 — Letting Go vs. Forcing Change 28:09 — Rebuilding Every Organ with Anti-Aging Work 33:51 — How to Actually Feel Emotions (Without Getting Stuck) 39:18 — Upgrading the Subconscious 45:02 — Final Thoughts and Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
14 Aug 52min
The New Poisons Lurking Around You – Save Your Longevity : 1313
Toxins you cannot see are damaging your health, wrecking your metabolism, and quietly accelerating aging. This episode reveals how to detect the new poisons lurking in your home, how they sabotage mitochondria and brain optimization, and the biohacking fixes that restore longevity, energy, and human performance. You’ll learn actionable strategies you can implement right away, from functional medicine detox protocols to supplements that protect your nervous system and upgrade neuroplasticity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alan Bell, an environmental health attorney and author of POISONED. Alan’s landmark legal work and decades of investigative experience have exposed some of the most dangerous everyday chemicals in modern life. After surviving his own severe toxic exposure, he’s dedicated his career to helping others identify hidden threats, fight back against corporate negligence, and restore their health through targeted biohacking and functional medicine. You’ll learn: • The most common invisible poisons in homes and how they impact metabolism, mitochondria, and brain optimization • Biohacking techniques for detox, from supplements to fasting and cold therapy • How to protect longevity and human performance with targeted functional medicine strategies • Why your sleep optimization, ketosis, and nootropics stack may fail without toxin removal • The connection between environmental toxins, neuroplasticity, and emotional resilience • How to use smarter not harder thinking to upgrade your biology for the long term This is essential listening for anyone serious about biohacking, brain optimization, hormone hacking, nootropics, functional medicine, emotional resilience, and building a state of unstoppable energy. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Alan Bell, Dave Asprey, environmental illness, toxic building syndrome, VOC exposure, multiple chemical sensitivity, U.S. chemical safety laws, environmental toxins, mast cell activation, mitochondrial health, ten most dangerous chemicals, biohacking detox, air filtration, flame retardant-free bedding, non-toxic cookware, chronic illness Thank you to our sponsors! Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY.BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Alan’s Website: https://alanbell.me/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:07 — Intro 3:45 — Life in a Bubble 5:40 — Building Syndrome Impact 7:04 — Legal Gaps 11:55 — Medical Blind Spots 13:04 — Chemicals + Mold 14:00 — Legal Barriers 17:15 — Environmental Disease Links 18:54 — Toxic Burden 20:53 — Media Awareness 21:55 — Hollywood Hazards 24:00 — MCS & Fibromyalgia 26:04 — Recovery Strategies 27:22 — Mast Cell Science 38:15 — Biohacking & AI 40:17 — Top 10 Chemicals 44:00 — Reduce Exposure 48:45 — Detox & Travel 50:20 — Legal + Media Power 52:33 — Chemical Industry Truth 56:19 — Policy & Advocacy 58:12 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
12 Aug 58min
Jim Kwik: What I Take to Biohack Brain Speed and Focus : 1312
Want to think faster, remember more, and rewire your brain for high performance? This special archived episode breaks down the real nootropic stack, neuroplasticity tools, and brain optimization protocols Jim Kwik uses daily, plus the biohacking routines that rebuilt his cognition after traumatic brain injury. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with world-renowned brain coach Jim Kwik, bestselling author of Limitless and advisor to billionaires, athletes, and Hollywood performers. After being labeled “the boy with the broken brain” as a child, Jim transformed his life through functional medicine, nootropics, cold therapy, neurorehab, and smart supplementation. He’s now the go-to expert on learning how to learn, with cutting-edge insights on memory, speed reading, focus, and cognitive recovery. Together, they reveal the most effective supplements for brain optimization, how to stack smart drugs with sleep optimization, the surprising downside of alpha GPC, and why things like ketosis, mitochondrial support, and even Danger Coffee are essential for modern cognition. You’ll also hear why your brain speed depends on your metabolism, the forgotten science of post-traumatic growth, and how to combine breathing, fasting, and cold therapy for massive neuroplasticity gains. Jim also shares his Brain Animal system, a new way to personalize your learning, decision-making, and communication based on your unique cognitive style. From performance to parenting, he shows how your “brain type” influences every part of life and how to hack it for focus, clarity, and flow. This episode is packed with high-impact strategies for biohacking your brain, improving human performance, upgrading memory, and building real resilience using smarter not harder protocols. You’ll Learn: • What Jim Kwik takes daily for brain speed, cognition, and mental stamina • The exact nootropics Dave Asprey uses (and the ones he avoids) • How sleep apnea nearly destroyed Jim’s performance and how he hacked it • The connection between mitochondria, memory, and metabolism • Why brain inflammation blocks focus and cognitive clarity • When to use cold therapy, hyperbaric oxygen, and stem cells for brain repair • How to know if your brain needs more acetylcholine and what happens if you overdo it • The best biohacking tools for focus, speed reading, learning, and flow state • Why your brain animal determines how you learn, lead, and connect Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keyword Index: Acetylcholine supplements, Alpha GPC vs CDP choline, Post-traumatic growth brain, Stem cells for brain repair, Hyperbaric oxygen therapy for TBI, Brain inflammation supplements, Learning disabilities recovery, Best supplements for neurogenesis, Brain fog biohacks, Brainwave training programs, Smart drug protocols, Cognitive stack routines, Mitochondrial support for cognition, Electrolytes for brain performance, Danger Coffee brain benefits, ADHD nootropics protocol, Sleep apnea and cognition, High dopamine supplements, Brain types and learning styles, Upgrade Labs review Thank you to our sponsors! Generation Lab | Go to http://generationlab.com/, use code Dave20 for $20 off, and see what your body’s really doing behind the surface. GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what’s in your air. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. Resources: • Jim's Website: https://www.jimkwik.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Introduction & Brain Health • 0:47 — Childhood Injury & Struggles • 2:53 — Adversity & Purpose • 6:31 — Nootropics & Optimization • 18:49 — Daily Biohacking Habits • 32:14 — Exercise & Brain Function • 34:21 — Learning & Cognition • 38:06 — Sleep & Resilience • 41:41 — Brain Types Explained • 52:16 — Parenting & Neuroplasticity • 57:19 — Limitless Update & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
8 Aug 59min
Why I Inject a “Female Hormone” 3x a Week (Nootropic Hacking) : 1311
What if the most powerful upgrades for brain energy, metabolism, and drive aren’t in mainstream medicine, but in rare peptides and misunderstood hormones? In this episode, you’ll discover the cutting-edge compounds, nootropics, and hormonal strategies that elite biohackers are using right now to optimize every part of their biology. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jay Campbell and Hunter Williams, co-founders of BioLongevity Labs—a performance biotech company creating oral peptide-based products like BioMind and BioGutPro. Jay is a globally recognized expert in testosterone optimization, author of The TOT Bible, and a leading voice in hormone and peptide therapeutics. Hunter is a high-performance coach and podcast host focused on metabolism, mindset, and men’s health through functional medicine and advanced supplementation. In this high-energy, high-clarity conversation, the trio explore what’s working right now in advanced human performance, spanning hormone synergy, mitochondrial enhancement, libido compounds, nootropics, and muscle-preserving stacks. You’ll hear why Dave injects estradiol three times per week, how Jay and Hunter use oral bioregulators to improve gut-brain signaling, and what peptides are quietly reshaping the future of health. You’ll Learn: • Who should use estradiol—and how it can protect brain performance in men • The real role of testosterone and estradiol synergy in male health and longevity • How BioLongevity Labs is innovating with oral peptide delivery for cognitive and gut health • Why peptides like BPC‑157, TB‑500, PT‑141, and SS‑31 are changing mitochondrial care • The truth about Melanotan‑1, SLU, AOD‑9604, GW‑501516, and BAM‑15 • What makes BioMind and BioGutPro different from standard nootropic or probiotic stacks • Why libido and metabolic health are deeply connected • The dangers of unvetted peptide sources—and what to look for in quality and bioavailability This is essential listening for anyone serious about biohacking, hormone optimization, mitochondrial support, brain energy, nootropics, neuroplasticity, functional medicine, sleep optimization, metabolism, and smarter-not-harder living. Keyword Index: estradiol for men, Dave Asprey hormone therapy, Jay Campbell BioLongevity Labs, Hunter Williams performance coaching, BPC‑157 recovery peptide, TB‑500 tissue regeneration, PT‑141 libido peptide, SS‑31 mitochondria peptide, Melanotan‑1 for skin and mitochondria, SLU stack, AOD‑9604 fat loss peptide, GW‑501516 Cardarine, BAM‑15 mitochondrial uncoupler, oral peptide delivery, BioMind brain supplement, BioGutPro gut-brain axis, testosterone estradiol synergy, mitochondrial uncoupling, nootropic peptide stacks, performance biohacking supplements Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! Puori | Head to http://puori.com/dave for 20% off, including subscriptions. Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • BioLongevity Labs Website: https://biolongevitylabs.com/?ref=DAVE# • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 – Trailer 01:00 – Introduction & Early Days of Biohacking 02:03 – Peptides 101: Foundations and Frameworks 03:06 – Peptides for Healing, Cognition, and Longevity 07:56 – Bioregulators and Russian Innovations 11:07 – Side Effects and Safety of Peptides 22:27 – Oral Peptides and Product Innovations 27:41 – Body Composition, Hormones, and Fat Loss 32:02 – Testosterone, Estrogen, and Male Health Protocols 45:03 – Peptides for Performance, Fat Loss, and Longevity 1:26:32 – Loose Skin, Surgery, and Body Transformation 1:38:00 – Closing Thoughts & Product Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
7 Aug 1h 38min
Top 5 Dopamine Boosting Biohacks for Superhuman Energy : 1310
Ready to learn about the secret compounds, molecules, nootropics, and stacks that Big Pharma doesn’t want you to know about? This episode is packed with the exact dopamine-boosting compounds, stacks, and biohacking protocols that top performers are using to supercharge human performance, brain optimization, and long-term resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Lucas Aoun, Australia’s leading biohacker and founder of Ergogenic Health. Known for his fearless, data-driven experimentation, Lucas specializes in nootropics, dopamine modulation, mitochondria, and functional medicine. He’s spent over a decade testing underground compounds, natural molecules, and hormone-based strategies to achieve elite-level brain and body performance. Together, they explore Russian-developed enhancers like Bromantane and ITPP, and reveal how these rare compounds impact dopamine regulation, neuroplasticity, and mental drive. You’ll learn how to upregulate tyrosine hydroxylase (your brain’s dopamine switch), build targeted stacks for motivation and confidence, and avoid the common supplements that quietly kill your ambition. They also dive into the connection between dopamine and testosterone, explaining how to rewire hormonal feedback loops to reclaim masculinity, energy, and purpose. From libido hacks and prolactin suppression to stacking dopamine with GABA and acetylcholine, this episode gives you a complete system for motivation mastery. Other key topics include the dangers of chronic ashwagandha use, sleep optimization for dopamine recovery, the truth about adaptogens and cold therapy, ketosis, fasting, DHT science, ciproheptadine microdosing, and why mitochondrial support is essential for long-term performance and metabolism. You’ll Learn: • The #1 Russian compound for explosive dopamine and drive • Why most “calming” supplements destroy your ambition • How dopamine and DHT shape masculinity and performance • Advanced biohacks for sleep, motivation, libido, and mood • The truth about serotonin dominance and how to escape it • Which functional medicine tools enhance brain energy and metabolism • How to build your own dopamine protocol using proven nootropics • Why mitochondrial health is the hidden key to motivation and mood This is essential listening for anyone serious about biohacking, brain optimization, hormone hacking, nootropics, functional medicine, emotional resilience, and building a state of unstoppable energy. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE. Resources: • Lucas’s Website: https://www.boostyourbiology.com/ • Lucas’s YouTube: https://www.youtube.com/c/boostyourbiology • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Tags: dopamine boosters, russian nootropics, bromantane benefits, biohacking dopamine, boost motivation naturally, dopamine stack, lucas aoun podcast, dave asprey dopamine, nootropics for energy, secret russian compounds, brain optimization, biohacking supplements, increase dopamine levels, functional medicine hacks, hormone optimization, dopamine and testosterone, neuroplasticity hacks, superhuman energy, underground nootropics, dopamine protocols See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
5 Aug 1h 4min
