Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer
Huberman Lab31 Mars

Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

My guest is Dr. Chris Palmer, M.D., a board-certified psychiatrist and professor at Harvard Medical School. He explains how specific nutrition, exercise, supplement-based, and other factors can improve mitochondrial health and thereby provide relief from adult and childhood ADHD, bipolar disorder, schizophrenia, and symptoms of autism. We discuss mitochondrial biology, whether vaccines can impact inflammation and mitochondrial health, and the potential ramifications. We also review creatine, methylene blue, and urolithin A, as well as the role of B vitamins and iron in treating depression. By the end of this episode, you will understand the powerful link between metabolic health and mental health, and the lifestyle, dietary, and other factors you can leverage to help overcome common mental health challenges and disorders. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Our Place: https://fromourplace.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Dr. Chris Palmer 00:02:15 Integrating Metabolic, Mental & Physical Health; Childhood Trauma & Risk 00:10:46 Sponsors: Our Place & LMNT 00:13:44 Depression Causes, Molecule Model?, Neuroplasticity?; Metabolism 00:22:20 Mitochondrial Functions, Stress Response, Mental Health 00:31:09 Sponsors: AG1 & Eight Sleep 00:33:59 Mitochondrial Health & 6 Pillars of Lifestyle Medicine 00:39:38 Stimulants, Mitochondria, Dopamine; Alcohol 00:45:47 Nicotine; Substance Use, Metabolic Health & Disease 00:52:23 Children, Energy & Metabolic Function; Diseases of Aging & Mental Disorders 00:59:18 Sponsor: Function 01:01:06 Diet & Metabolism; Ultra-Processed Foods, Additives, GRAS 01:09:30 Rebellious Spirit, Ultra-Processed Foods & Food Industry Funding 01:19:14 Ketogenic Diet, Epilepsy, Schizophrenia, Bipolar 01:22:52 Ketogenic Diet, Fasting & Mitochondria; Gut Microbiome, Brain Metabolism 01:30:06 Low-Fat Diets; Tool: Occasional Fasts; Ketogenic Diet; Intermittent Fasting 01:38:40 Nutrition Research, Food Industry Lobbyists; Ultra-Processed Foods, Addiction 01:46:55 Creatine & Mitochondrial Health 01:52:34 Methylene Blue & Mitochondria; Serotonin Syndrome 02:02:58 Urolithin A, Mitochondria Function; Supplements & Appropriate Use 02:11:14 Vitamin Deficiencies, Iron Deficiency 02:16:06 Vitamin B12 & Folate Deficiency, Autoimmune Disorders 02:24:48 Mental Illness & Root Causes 02:29:02 Vaccines, Inflammation, Mitochondria, Autism 02:39:17 Neurodevelopmental Disorder Onset & Follow-Up 02:45:31 Vaccines, Autism, Future Research; Mother Obesity & Diabetes 02:51:23 Father Obesity & Autism; Poor Metabolic Health, Blood Biomarkers 02:56:44 Assessing Metabolic Health & Biomarkers; National Institutes of Health (NIH) 03:02:59 Future Directions, Bridging Mental & Physical Health 03:09:27 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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Dr. David Buss: How Humans Select & Keep Romantic Partners in Short & Long Term

Dr. David Buss: How Humans Select & Keep Romantic Partners in Short & Long Term

In this episode, my guest is Dr. David Buss, Ph.D., Professor of Psychology at the University of Texas, Austin, and one of the founding members of the field of evolutionary psychology. Dr. Buss describes his work on how people select mates for short and long-term relationships, the dynamics of human courtship, and mate value assessment — meaning how people measure up as potential partners. We also discuss the causes of infidelity and differences for infidelity in men and women. He explains how people evaluate and try to alter other people’s mate value as a means to secure and even poach mates. We discuss monogamous and non-monogamous relationships in humans. And we discuss what Dr. Buss calls “the dark triad” — features common in stalkers and narcissists that relate to sexual and psychological violence in relationships. This episode is sure to be of interest to anyone single or in a relationship who seeks to know how people select mates and anyone who is interested in forming and maintaining healthy romantic partnerships.  Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Introducing Dr. David Buss   00:04:27 Sponsors: AG1, LMNT & Waking Up 00:08:33 Choosing a Mate   00:13:40 Long Term Mates: Universal Desires   00:18:31 What Women & Men Seek in Long-Term Mates   00:25:10 Age Differences & Mating History   00:32:20 Deception in Courtship   00:37:30 Emotional Stability   00:38:40 Lying About Long-Term Interest   00:41:56 Short-Term Mating Criteria, Sliding Standards & Context Effects   00:46:25 Sexual Infidelity: Variety Seeking & (Un)happiness & Mate Switching   00:54:25 Genetic Cuckolds, How Ovulation Impacts Mate Preference   00:57:00 Long-Term vs. Short-Term Cheating, Concealment   00:59:15 Emotional & Financial Infidelity   01:04:35 Contraception   01:06:22 Status & Mating Success   01:10:10 Jealousy, Mate Value Discrepancies, Vigilance, Violence   01:24:13 Specificity of Intimate Partner Violence   01:25:12 Mate Retention Tactics: Denigration, Guilt, Etc.   01:27:33 Narcissism, Machiavellianism, Psychopathy   01:33:25 Stalking   01:39:15 Influence of Children on Mate Value Assessments   01:43:24 Attachment Styles, Mate Choice & Infidelity   01:46:40 Non-Monogamy, Unconventional Relationships   01:54:00 Mate Value Self Evaluation, Anxiety About the Truth   02:02:12 Self Deception   02:05:35 The Future of Evolutionary Psychology & Neuroscience   02:06:56 Books: When Men Behave Badly, The Evolution of Desire, Textbooks   02:10:42 Concluding Statements, Zero-Cost Support: Subscribe, Sponsors, Supplements   Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices

29 Nov 20212h 10min

The Science of Gratitude & How to Build a Gratitude Practice

The Science of Gratitude & How to Build a Gratitude Practice

In this episode, I discuss the science of gratitude, which has been shown in peer-reviewed studies to have tremendous positive effects on mental and physical health. I explain, however, that most commonly used gratitude practices are ineffective (such as gratitude lists). The key elements of highly effective gratitude practices are described, including the essential need for story (narrative), receiving or perceiving gratitude rather than giving it, and the role that theory of mind plays in this context. I also discuss why we can't simply make up feelings of gratitude and how reluctance undermines the process. I also explain the neural circuit mechanisms that underlie the reductions in fear and increases in motivation and lowering of inflammatory chemicals that effective narrative-based gratitude can trigger. Throughout the episode, I use the science of gratitude to design a brief but highly effective protocol.  Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Introduction: Gratitude Science & Surprises   00:01:50 Controlling Heart Rate with Story   00:04:48 Sponsors: AG1, LMNT & Waking Up 00:09:11 Major, Long-Lasting Benefits of Gratitude Practice   00:12:20 Prosocial vs. Defensive Thinking, Behaviors, & Neural Circuits   00:17:50 Why We All Need an Effective Gratitude Practice   00:21:22 Neurochemistry & Neural Circuits of Gratitude   00:25:10 Prefrontal Cortex Set Context   00:30:10 Ineffective Gratitude Practices; Autonomic Variables   00:34:55 Key Features of Effective Gratitude Practices: Receiving Thanks & Story   00:42:30 Theory of Mind Is Key   00:45:50 Building Effective Gratitude Practices: Adopting Narratives, Duration   00:52:28 Narratives That Shift Brain-Body Circuits   00:56:15 You Can’t Lie About Liking Something; Reluctance in Giving   00:59:55 How Gratitude Changes Your Brain: Reduces Anxiety, Increases Motivation   01:03:00 5 Minutes (Is More Than Enough), 3X Weekly, Timing Each Day   01:05:44 Empathy & Anterior Cingulate Cortex   01:07:35 Reducing Inflammation & Fear with Gratitude   01:10:56 Serotonin, Kanna/Zembrin   01:16:00 Neuroplasticity, Pharmacology, Brain Machine Interfaces   01:18:50 The Best Gratitude Practices: & How To, My Protocol   01:24:25 Subscribe & Feedback, Supporting Sponsors, Supplements   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

22 Nov 20211h 22min

Time Perception & Entrainment by Dopamine, Serotonin & Hormones

Time Perception & Entrainment by Dopamine, Serotonin & Hormones

In this episode, I discuss how our brain and body track time and the role that neurochemicals, in particular dopamine and serotonin, but also hormones such as melatonin, allow us to orient ourselves in time. I review the three types of time perception: of the past, of the present, and the future, and how dopamine and serotonin adjust both our perception of the speed of the passage of time and our memory of how long previous experiences lasted. I also discuss circannual entrainment, which is the process by which our brain and body are matched to the seasons, and circadian (24 hours) entrainment, both of which subconsciously adjust our perceived measurement of time. I explain the mechanisms of that subconscious control. And I cover the ultradian (90 minutes) rhythms that govern our ability to focus, including how to track when these 90-minute rhythms begin and end for the sake of work and productivity. I include ten tools based on the science of time perception that you can apply to enhance productivity, creativity, and relationships in various contexts.  Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Introducing Time Perception, Note on Fasting & Supplements   00:05:28 Sponsors: AG1, LMNT & Waking Up 00:09:25 Entrainment, Circannual Entrainment, Melatonin   00:13:20 Seasonal Oscillations in Testosterone & Estrogen, Tool 1   00:16:06 Circadian Timing, Tools 1, 2, 3 (for Circadian Entrainment)   00:21:13 Tool 4: Timing Physical Activity; Tool 5: Timing Eating Window   00:23:00 When Circadian Entrainment Is Disrupted, Time Perception Suffers   00:25:00 Tool 6: Ultradian (90min) Cycles & Focus   00:31:42 Our Sense of the Passage of Time: Present, Prospective, Retrospective   00:34:40 Dopamine (& Nor/epinephrine) Lead to Time Overestimation; Frame Rate   00:37:18 Serotonin & Time Underestimation; Decreased Frame Rate   00:39:10 Dopamine vs. Serotonin Across the Day; Tool 7: When to Do Rigid vs. Creative Work   00:42:38 Example of Tool 7   00:43:38 How Sleep Deprivation Degrades Performance   00:44:38 Trauma, “Over-clocking” & Memories; Adjusting Rates of Experience   00:50:04 Why Trauma Involves Dopamine & Epinephrine, Arousal   00:51:03 Dopamine, Spontaneous Blinking & Time Perception; Tool 8   00:53:38 Deliberate Cold Exposure, Dopamine, Tool 9: Adjusting Frame Rate in Discomfort   00:56:30 Fun “Feels Fast” BUT Is Remembered as Slow; Boring Stuff “Feels Slow,” Recall as Fast   01:00:54 Retrospective Time, Context Variation & Enhanced Bonding with Places & People   01:03:00 Dopamine Release Resets the Start of Each Time Bin on Our Experience   01:07:40 Habits & Time Perception; Tool 10 (Setting Functional Units of Each Day)   01:11:58 Synthesis & Book Suggestion (Your Brain Is a Time Machine by D. Buonomano)   01:12:27 Supporting the HLP: Subscribe, Instagram, Supplements   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

15 Nov 20211h 11min

Dr. Duncan French: How to Exercise for Strength Gains & Hormone Optimization

Dr. Duncan French: How to Exercise for Strength Gains & Hormone Optimization

In this episode, I talk to Dr. Duncan French, Ph.D., the Vice President of Performance at the UFC Performance Institute and a world-class performance specialist. We discuss specific resistance (weight) training regimens for increasing testosterone in men and women and how to vary mechanical loads and rest between sets and workouts to optimize hormone output and training results. We also discuss how stress-induced "catecholamines" can increase testosterone or decrease it, depending on duration and mindset. And we discuss specific cold- and heat- therapies for increasing resilience, reducing inflammation, heat shock proteins and more. We discuss nutrition for training and how to match nutrition to training goals and metabolic flexibility. We discuss mental focus and how long to train for skill development. Finally, we discuss how mixed martial arts and the UFC Performance Institute are a template for exploring human performance more generally. This episode is intended for anyone interested in athletic and mental performance: athletes, students, and recreational exercisers and includes both science and many practical tools people can apply in their own training.  Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Dr. Duncan French   00:02:44 Sponsors: AG1, LMNT & Waking Up 00:05:44 Duncan’s Background in Exercise Science   00:11:45 How Certain Exercises Increase Testosterone   00:16:22 What Kind of Training Increases Testosterone & Growth Hormone?   00:20:19 Intensity: Mechanical Load; Volume: Metabolic Load; Inter-set Rest Periods   00:25:25 Training Frequency & Combining Workout Goals   00:29:35 How Stress Can Increase or Decrease Testosterone   00:36:55 Using Cold Exposure for Mindset, Anti-Inflammation, Muscle-Growth   00:46:55 Skill Development   00:50:05 Why Hard Exercise Creates Brain Fog: Role of Nutrition   00:53:55 Low-Carbohydrate Versus All-Macronutrient Diets on Performance   00:56:15 Ketones & Brain Energy, Offsetting Brain Injury; Spiking Glucose During Ketosis   00:59:13 Metabolic Efficiency, Matching Nutrition to Training, “Needs Based Eating”   01:05:00 Duncan’s Work with Olympic Athletes, NCAA, UFC (Ultimate Fighting Championship)   01:08:00 Why UFC & MMA (Mixed-Martial Arts) Are So Valuable for Advancing Performance   01:12:40 Voluntarily Switching Between Different States of Arousal   01:14:30 Heat, Getting Better at Sweating, Heat Shock Proteins, Sauna   01:20:12 Using Rotating 12-Week Training Programs; Logging Objective & Subjective Data   01:24:07 Surprising & Unknown Aspects of The UFC and UFC Performance Institute   01:27:45 Conclusions, Zero-Cost Support, Sponsors, Supplements, Instagram   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

8 Nov 20211h 28min

Using Your Nervous System to Enhance Your Immune System

Using Your Nervous System to Enhance Your Immune System

This episode teaches you a lot about the immune system, immune-brain interactions and offers 12 potential tools for enhancing immune system function. I discuss how our immune system works and science-supported tools we can use to enhance our immune system. I discuss the innate and adaptive immune systems and our various microbiomes-- not just in our gut but also in our nose, eyes and mouth and how to keep them healthy. And I review how specific patterns of breathing and foods maintain a healthy mucosal barrier that is crucial for fighting infections. I discuss how certain neurochemicals called catecholamines enhance our immune system function and how to use specific breathing protocols, types and timing of heat and cold exposure, and, if appropriate, supplementation to activate catecholamines. I also discuss the role and use of serotonin for the sake of accessing the specific types of sleep for recovering from illness, and I discuss how to increase glymphatic "washout" of brain debris during sleep. I also review fever, the vagus nerve and the use of atypical yet highly effective compounds for rhinitis (nasal inflammation). Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 The Mind & Immune System, New Findings: Acupuncture & Fascia   00:03:16 Sponsors: AG1, LMNT & Waking Up 00:07:41 Foundational Tools & Practices for a Healthy Immune System   00:11:20 Immune System Basics: Skin/Mucous, Innate & Adaptive Immune System   00:17:08 Killer Cells, Complement Proteins (“Eat Me!” Signals), Cytokines (“Help Me!” Signals)   00:21:06 The Adaptive Immune System: Antibodies   00:28:00 Tool 1: Nasal Microbiome and “Scrubbing” Bacteria & Viruses; Nasal Breathing   00:30:33 Tools 2 & 3: (Not) Touching Your Eyes; Gut Microbiome & Fermented Foods   00:34:20 Some Interleukins Are Anti-Inflammatory   00:34:56 Sickness Behavior   00:39:08 Some People Seek Care When Sick, Others Want to be Alone   00:42:00 Sickness Behavior & Depression: Cytokines   00:43:40 Reduced Appetites When Sick: Protein, Iron, Libido   00:46:45 Vagus-Nerve Stimulation: Fever, Photophobia, Sleepiness   00:53:03 Humoral (Blood-Borne) Factors, & Choroid Change Your Brain State   00:55:04 Tools 4, 5: Reducing Sickness: Glymphatic Clearance, Pre-Sleep Serotonin, 5HTP   01:07:03 Tool 6: Hot Showers, Saunas, Baths & Cortisol, Heat-Cold Contrast   01:10:53 Feed a Fever & Starve a Cold (?), Adrenaline   01:12:36 Tool 7: Activating Your Immune System w/Cyclic-Hyperventilation, Alkalinity   01:29:10 Brain Chemicals & Cyclic-Hyperventilation; Catecholamines, Dopamine   01:32:10 Mindsets & Immune Function; Yes, You Can Worry Yourself Sick   01:37:00 Tool 8: Healthy Mindsets, Hope, Dopamine; Tool 9: Tyrosine; Tool 10: Cold Exposure   01:42:05 Once You’re Already Sick: Accelerating Recovery; Tool 11: Spirulina, Rhinitis   01:46:09 Histamines, Mast Cells   01:49:22 Tool 12: Acupuncture: Mechanism for How It Reduces Inflammation; Fascia, Rolfing   01:53:40 Mechanistic Science & Ancient Practices   01:58:00 Synthesis, Ways to Support Us (Zero-Cost), Sponsors, Supplements, Social Media   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

1 Nov 20211h 57min

Dr. Samer Hattar: Timing Your Light, Food, & Exercise for Optimal Sleep, Energy & Mood

Dr. Samer Hattar: Timing Your Light, Food, & Exercise for Optimal Sleep, Energy & Mood

In this episode, I host Dr. Samer Hattar, Ph.D., Chief of the Section on Light and Circadian Rhythms at the National Institute of Mental Health. Dr. Hattar is a world-renowned expert on how viewing light at particular times adjusts our mood, ability to learn, stress and hormone levels, appetite, and mental health. We discuss how to determine and use your individual light sensitivity to determine the optimal sleep-wake cycle for you. We also discuss how to combine your light viewing and waking time with the timing of your food intake and exercise in order to maximize mental and physical functioning. Dr. Hattar is credited with co-discovering the neurons in the eye that set our circadian clocks and regulate mood and appetite. He explains why even a small shift in daylight savings leads to outsized effects on our biking because of the way that our cells and circadian clocks integrate across many days. And he offers precise tools to rapidly adjust to jet lag, shift work, and reset your clock after a late night of work or socializing. This episode is filled with cutting-edge data on the biological mechanisms of human physiology and practical tools for people of all ages.  Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Introducing Dr. Samer Hattar, Ph.D.   00:02:33 Sponsors: AG1, LMNT & Waking Up 00:06:15 Light, Circadian (24-hour) & Circannual (365-day) “Photoentrainment”   00:14:30 Neurons in Our Eyes That Set Our Body Clocks: Similar to Frog Skin   00:18:55 What Blind People See   00:20:15 When, How & How Long to View Light for Optimal Sleep & Wakefulness   00:30:20 Sunlight Simulators, Afternoon Light Viewing, Naps   00:33:48 Are You Jet Lagged at Home? Chronotypes & Why Early Risers Succeed   00:38:33 How to Decide Your Best Sleep-Wake Schedule; Minimal Light Test   00:42:16 Viewing Light in Middle of Day: Mood & “Light Hunger”   00:44:55 Evening Sunlight; Blueblocker Warning   00:48:57 Blue Light Is Not the Issue; Samer’s Cave; Complete Darkness   00:53:58 Screens at Night   00:56:03 Dangers of Bright Light Between 10 pm and 4 am: Mood & Learning   01:01:05 The Tripartite Model: Circadian, Sleep Drive, Feeding Schedules   01:05:05 Using Light to Enhance Your Mood; & The Hattar-Hernandez Nucleus   01:07:19 Why Do We Sleep?   01:08:17 Effects of Light on Appetite; Regular Light & Meal Times   01:18:08 Samer’s Experience with Adjusting Meal Timing   01:22:51 Using Light to Align Sleep, Mood, Feeding, Exercise & Cognition   01:30:15 Age-Related Changes in Timing of Mental & Physical Vigor   01:31:44 “Chrono-Attraction” in Relationships; Social-Rhythms   01:33:40 Re-setting Our Clock Schedule; Screen Devices Revisited   01:37:50 How Samer Got into the Study of Light   01:39:33 Clock Gene mRNAs & More Accurate Biomarkers   01:41:08 Light as Medicine   01:42:48 ADHD (Attention-Deficit Hyperactivity Disorder)   01:43:35 How to Beat Jet Lag: Light, Temperature, Eating   01:50:44 Vigor: The Consequence of Proper Timing   01:52:15 Waking in the Middle of the Night: When Your Nightly Sleep Becomes a Nap   01:54:10 Melatonin, Pineal Calcification   01:55:25 Our Seasonal Rhythms: Mood, Depression, Lethargy & Reproduction   01:59:08 Daylight Savings: Much Worse Than It Might Seem   02:05:27 Eye Color & Sensitivity to Light, Bipolar Disorder   02:09:28 Spicy Food, Genetic Variations in Sensory Sensitivity   02:10:52 Synthesizing This Information, Samer on Twitter, Instagram   02:13:00 Conclusions, Ways To Support the Huberman Lab Podcast & Research   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

25 Okt 20212h 12min

Nutrients for Brain Health & Performance

Nutrients for Brain Health & Performance

This episode I describe science-supported nutrients for brain and performance (cognition) and for nervous system health generally. I describe 10 tools for this purpose, including specific amounts and sources for Omega-3 fatty acids which make up the "structural fat" of neurons (nerve cells) and allow them to function across our lifespan. I also review data on creatine, phosphatidylserine, anthocyanins, choline, glutamine and how they each impact brain function in healthy people seeking to reinforce and improve their cognition and in those combatting cognitive decline. I describe both food-based and supplement-based sources for these compounds, and their effective dose ranges based on peer-reviewed literature. Then I review the 3 factors: gut-brain signaling, perceived taste, and learned associations that combine with the metabolic and blood-sugar-elevating effects of food to determine what foods we seek and prefer. Amazingly, it's not just about what tastes good to us. Next, I explore how we can leverage the neural circuits of learned food preference toward seeking and enjoying the right foods for brain health and performance. I also review new data on non-caloric sweeteners and why consuming them with glucose-elevating foods can be detrimental, in some cases rapidly leading to insulin dysregulation. This episode covers more than 10 actionable tools for those seeking to improve and/or maintain brain function, and it explains modern neuroscience underlying of our sense of taste, our food seeking preferences and brain metabolism. Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Food & Brain Function Introduction   00:02:08 Summary: Critical Aspects of Time Restricted Feeding/Fasting   00:04:36 Sponsors: AG1, LMNT & Waking Up 00:08:24 Neuroplasticity Super Protocol (Zero-Cost Tools) Online   00:09:22 Eating to Enhance Brain Function & Foundational Aspects of Brain Health   00:13:00 Eating Fats for Brain Health, EFAs Phospholipids (Tool 1: 1-3g EPA Omega-3/day)   00:20:35 Phosphatidylserine (Tool 2: 300mg/day)   00:22:15 Choline, Egg Yolks (Tool 3: 1-2g/day Threshold)   00:28:26 Hydration & Electrolytes (Tool 4)   00:29:50 Liquid Fish Oil/Capsules (2-3g EPA per day; 300mg Alpha GPC 2-4X/week)   00:32:22 Creatine for Cognition (Tool 5: 5g/day)   00:36:28 Anthocyanins, Dark Skin Berries (Tool 6: 10mg/day (Extract), 1-2 cups Berries)   00:41:19 L-Glutamine (Tool: 1-10g/day) & Offsetting Apnea & Inflammation   00:49:23 Neural Basis of Food Preference, Yum, Yuck, Meh; Taste, Guts, & Beliefs   00:55:25 Taste is 100% In Your Head   00:59:50 Gut Neurons Controlling Food Preference: Neuropod Cells; (Tool 7: Fermented Foods)   01:06:14 Capsule Probiotics, Brain Fog   01:07:16 Learning to Like Specific Tastes: Sweetness & Brain Metabolism   01:12:11 Hard-Wiring & Soft-Wiring   01:13:25 Artificial & Non-Caloric Sweeteners: Safe or Harmful Depends on (Glucose) Context   01:18:15 Non-Caloric Sweetener & Insulin; (Tool 8: Don’t Have w/Glucose Elevating Foods)   01:22:17 Beliefs & Thoughts; The Insula; (Tool 9: Pairing-Based Reshaping Food Preferences)   01:30:42 Liking Neuro-Healthy Foods & Bettering Brain Metabolism (Tool 10); Food Wars   01:36:05 Food Reward & Diabetes, Obesity; Important Review Article (See Caption)   01:38:28 Synthesis, Zero-Cost Support, Future Topic Suggestions, Sponsors, Supplements   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

18 Okt 20211h 37min

Effects of Fasting & Time Restricted Eating on Fat Loss & Health

Effects of Fasting & Time Restricted Eating on Fat Loss & Health

This episode I discuss the science and practice of fasting also called time-restricted feeding. I review the data on how limiting food intake to specific portions of every 24-hour cycle (or fasting longer) impacts weight loss, fat loss specifically, liver health, mental focus, muscle, longevity and more. I explain how "fasted" is contextual, and relates to blood glucose levels and their downstream effects, and how the depth of fasting can be adjusted with behaviors such as different types of exercise, or with glucose disposal agents. I also discuss the optimal fasting protocol: and both the absolute (non-negotiable) and variable (contextual) features of a fasting/time-restricted-feeding protocol that will allow you to get the most benefits. I also discuss what does and does not break a fast, the effects of fasting on hormones like testosterone and cortisol and on fertility. I also review how different feeding windows of 8 or 10 or 4 hours differentially impact the effects of fasting, and why the classic 8 hour feeding window came to be but also might be ideal. I discuss mechanisms and offer tools to discern the optimal fasting duration and timing for you.  Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Introduction, Blood Glucose & Mortality, Mice Vs. Humans   00:06:18 Sponsors: AG1, LMNT & Waking Up 00:09:42 Neuroplasticity Protocols & Online Lecture   00:11:20 Feeding, Fasting, Performance   00:13:50 Calories-In, Calories-Out (CICO); Perfect Diets   00:19:48 Feeding-Induced Health Conditions   00:25:33 Time Restricted Eating: When We Eat Is Vital   00:29:45 The Eight Hour Feeding Window   00:31:26 Feeding Deep Into the Night Is Bad (In Humans)   00:36:33 Liver Health   00:39:45 Time Restricted Feeding Protocol: Rules   00:41:35 When to Start & Stop Eating   00:45:38 Gastric Clearance, Linking Fasting to Sleep   00:52:35 Effects of Specific Categories of Food   00:55:40 Precision In Fasting: Protocol Build   00:59:30 4-6 Hour Feeding Windows   01:03:08 Protein Consumption & Timing for Muscle   01:08:13 How to Shift Your Eating Window   01:13:20 Glucose Clearing, Exercise & Compounds   01:22:37 Blood Glucose: Monitoring, mTOR & Related Pathways   01:27:40 Gut Health: Fasting, Clock Genes and Microbiota   01:29:15 Non-Alcoholic Fatty Liver   01:32:00 Effects of Fasting on Hormones: Testosterone, Cortisol   01:38:40 Fertility   01:41:50 8-Hour Feeding Window: Weight Loss Without Calorie Counting   01:43:20 Eating Every-Other-Day   01:45:29 Adherence   01:47:15 Mental Focus & Clarity   01:49:12 Enhancing Weight Loss from Body Fat: Hepatic Lipase   01:53:15 What Breaks a Fast? Rules & Context   01:58:50 Artificial Sweeteners, Plant-Based Sweeteners   02:01:42 Glucose Clearing II, Cinnamon, Acidity, Salt   02:06:42 My Circadian Clock, Zero-App   02:08:20 Odd (But Common) Questions   02:09:23 Effects of Sauna & Dehydration on Blood Glucose   02:11:12 The Ideal Fasting Protocol   02:24:00 More Resources, Ways to Support Us, Supplements   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

11 Okt 20212h 22min

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sexet
rss-vetenskapsradion
rss-vetenskapspodden
paranormalt-med-caroline-giertz
rss-i-hjarnan-pa-louise-epstein
bildningspodden
rss-vetenskapsradion-2
a-kursen
medicinvetarna
hacka-livet
dumforklarat
rss-spraket
vetenskapsradion