The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld  : 1265

The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld : 1265

For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we’ve been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging?

In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in microbiome innovation, to expose why most probiotics fail—and how one company’s scientifically validated approach could redefine your gut, brain, immune system, and even your metabolism.

You’ll learn how dysbiosis may be wrecking your brain without you knowing it, why your probiotic likely died in your stomach acid, and the secret to rebooting your microbiome after antibiotics, GLP-1 drugs, or years of toxic exposure. This isn’t just about digestion—your gut controls your cravings, energy, sleep, mood, and aging trajectory.

So what’s the one upgrade that can actually reset your gut… for good?

What You’ll Learn in This Episode:

• Why your gut—not your brain—is making most of your decisions

• How 93% of probiotics on the market fail before they reach your intestines

• The “AB 10” protocol that rebuilds your gut after antibiotics or SIBO

• What GLP-1 weight-loss drugs are doing to your microbiome (and how to stop it)

• The shocking gut–brain–heart axis connection you’ve never heard of

• Why inflammation, brain fog, and mood swings may start with leaky gut

• Which probiotic strains are clinically proven to improve cognition and mood

• What to do if you want to eat gluten again—or survive American wheat

• How a fermented papaya concentrate could replace your acid reflux meds

• Why optimizing your gut could extend your lifespan by 40%


***Get 20% off your next purchase by going to https://omnibioticlife.com/pages/dave-asprey/ or omnibioticlife.com/dave***

SPONSORS

-Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.

-Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.

Resources:

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

OMNi-BiOTiC's Instagramhttps://www.instagram.com/fatty15/

OMNi-BiOTiC's Website: https://omnibioticlife.com/

2025 Biohacking Conference: https://biohackingconference.com/2025

Danger Coffee: https://dangercoffee.com

Dave Asprey’s Website: https://daveasprey.com

Dave Asprey’s Linktree: https://linktr.ee/daveasprey

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com

Own an Upgrade Labs: https://ownanupgradelabs.com

Upgrade Labs: https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com


Timestamps:

00:00 – Trailer

03:15 – Intro

05:05 – Probiotics, Prebiotics, and Postbiotics Explained

08:21 – The Importance of Delivery Mechanisms

17:36 – Addressing SIBO and Gut Health Protocols

31:55 – The Impact of GLP-1 Drugs on Gut Health

39:26 – The Role of Gut Bacteria in Hunger and Fasting

40:01 – Painkillers and Gut Health: A Personal Experience

40:51 – The Dangers of Proton Pump Inhibitors

42:00 – The Importance of Stomach Acid

44:55 – Probiotics for Chronic Conditions

48:38 – The Impact of Glyphosate on Gut Health

57:04 – Alcohol and Gut Bacteria

01:02:01 – New Solutions for Acid Reflux

01:07:57 – The Future of Gut Health and Longevity

01:11:33 – Conclusion and Special Offer

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Avsnitt(1380)

Bulletproof Exec 37 w The Caltons.mp3

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The Caltons are among the world's leading experts on the topics of weight management, lifestyle medicine and micronutrient deficiency. Their high success rate working with adults and children to achieve sustainable weight loss and reverse health and disease conditions has made their consultancy highly sought after by celebrities, athletes and top corporate executives around the world. It is their belief that becoming micronutrient sufficient is the first step towards preventing and reversing many of today's most prevalent health conditions and diseases. In today's podcast, they discuss their new book, Rich Food, Poor Food, and go into a step-by-step guide of how to shop for food, make good choices, and discuss top micro-nutrient deficiencies.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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Podcast #36:Hacking your Biome with uBiome's Jessica Richman

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Jessica Richman started and sold her first company after high school. Returning to formal education, she attended Stanford University, where she earned degrees in Economics and Science, Technology & Society (emphasis in computer science). Along the way, she worked for Google, McKinsey, Lehman Brothers, the Grameen Bank, and top-tier Silicon Valley venture firms. Currently a doctoral student at Oxford University, her academic interests include social networks, innovation, collective intelligence, and entrepreneurship. uBiome is the world’s first effort to map the human microbiome with citizen science. While the sequencing of the human genome has provided invaluable knowledge, it is very difficult to change our own genetic makeup. The microbiome, in contrast, is much more easily changed through simple means such as healthful probiotic cultures and other lifestyle interventions. The microbiome thus may provide some of the most important medical breakthroughs of our era. uBiome will ultimately empower participants to manage their microbiomes to improve their health as well as make important scientific discoveries for humanity. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Jan 201331min

Podcast #35: Bulletproof Your Nervous System with Jay Schroeder

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World-class strength and neurological conditioning authority, and creator of new technology that stimulates rapid nervous system and cellular improvements He has studied the greatest training systems of the world, not to find the successes but to establish the point at which they failed. He then put together his system of training to overcome these points of failure. He has traveled to Eastern bloc countries and developed working relationships with some of the most knowledgeable in the field. He has designed unique protocols for use with his device as well as the typical equipment in the gym setting, as they relate to rehab strength, injury prevention and elite athletic mastery. Elite level pro athletes pay more than $50,000 to train with Jay. He has designed unique protocols for use with the ARP as well as the typical equipment in the gym setting, as they relate to rehab strength, injury prevention and elite athletic mastery. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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Podcast #34: The Perfect Health Diet with Paul Jaminet

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Paul Jaminet. Ph.D. was an astrophysicist at the Harvard-Smithsonian Center for Astrophysics, became a software entrepreneur during the Internet boom, and now provides strategic advice to entrepreneurial companies while pursuing research in economics. Paul’s experience overcoming a chronic illness has been key to his views of aging and disease, and in writing his new book Perfect Diet Solution. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Dec 201240min

Podcast #33: Injury prevention and Wellness with Dr. Justin Marchegiani

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Dr. Justin Marchegiani is a graduate of the University of Massachusetts at Amherst with a B.S. degree in Kinesiology and Pre-medical studies. Dr. Justin has completed his Doctorate degree in Chiropractic Medicine from Life West University. Dr. Justin has completed post graduate study in the area of clinical nutrition, exercise and functional medicine so he can offer the most cutting edge techniques to help address his patient’s growing health care needs. Justin is head of Just In Health Wellness Clinic, a leading systems and functional medical provider who treats patients and athletes using biohacking and quantification. He can help you Bulletproof your game through education on injury prevention and performance enhancement! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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Podcast #32: Hacking your Heart and Preventing Diabetes with Dr. Rocky Patel

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Dr. Patel is a Bulletproof Physician.  He is a family physician whose practice is focused on the prevention, early detection and treatment of Diabetes and Heart Attack.  He knows his stuff, he lost over 85 lbs practicing what he preaches. He uses Bulletproof diet principles in treating patients in his practice at risk for or who have developed diabetes and/or cardiovascular disease.   In addition, he is the chief medical officer for Heart Fit for Duty, providing similar services to the first responder community.  For those of you interested in WellnessFx in Arizona, he is a WellnessFX practitioner and his family medical practice is based in Gilbert, Arizona.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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Podcast #31: Hack Your Sleep with Dr. Jonathan Wisor, Ph.D.

Podcast #31: Hack Your Sleep with Dr. Jonathan Wisor, Ph.D.

Dr. Wisor is one of the foremost researchers on sleep and nervous system function.  His laboratory is funded by both the Department of Defense and the National Institute of Neurological Disorders and Stroke to apply molecular genetic and biochemical techniques to study sleep. Dr. Wisor comes on the show today to talk about how you can use biochemistry and the latest research to improve sleep and your quality of life. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Sep 20121h 16min

Podcast #30: Sweet Potato Power with Ashley Tudor

Podcast #30: Sweet Potato Power with Ashley Tudor

Ashley Tudor is a Design Strategist with the Spruce Street Institute where she works to create innovations in healthcare for doctors, patients and kids. She has worked with a wide range of Fortune 500 companies on a variety of projects including envisioning the future of cars, finding new ways for people to invest their money, designing ways to help food companies fight obesity, and coming up with new medical devices for primary care physicians. Ashley was named one of San Francisco’s Top Innovators in Health in 2010.Aside from her business exploits, Ashley is the author of Sweet Potato Power, a book aimed at promoting what she believes to be one of the healthiest and most high performance foods you can eat.  Ashley comes on Upgraded Self Radio to talk about how you can use the power of sweet potatoes to look, feel, and perform better. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Aug 20121h 12min

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