S6- E3.1 - Roundtable: Spotting Tomorrow’s Trends in Today's MASLD Studies

S6- E3.1 - Roundtable: Spotting Tomorrow’s Trends in Today's MASLD Studies

Send us a text Surfing the MASH Tsunami continues its coverage of the AASLD Emerging Trends Conference on MASLD, MetALD and ALD. This week, the panelists focus on what studies on bariatric surgery and drugs in development can tell us about future treatment and explore some clinical trial questions. Guest Surfers include Professor Aleksander Krag of the University of Southern Denmark, the current Secretary-General of EALS, hepatologist Alexander Lalos of Robert Wood Johnson hospital, and...

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S2-E23 - Wrapping up Day Two of the Fourth Global NASH Congress -- Drugs, lifestyles and Health policy

S2-E23 - Wrapping up Day Two of the Fourth Global NASH Congress -- Drugs, lifestyles and Health policy

Send us a text Ian Rowe and GenFit Global Diagnostics Leader Suneil Hosmane join Louise and Roger as they keep discussing Day Two of the 4th Global NASH Congress. On April 29, over 175 NASH stakeholders from across the globe met virtually to hear 20 presentations from leaders in academia and industry. SurfingNASH selected 9 presentations to discuss in a session recorded right after the conference concluded. When the five panelists got together, the discussion extended to 90 minutes...too lon...

1 Maj 202144min

S2-E22 - Day Two at the 4th Global NASH Congress -- many New Drugs and Non-Pharmacologic Interventions

S2-E22 - Day Two at the 4th Global NASH Congress -- many New Drugs and Non-Pharmacologic Interventions

Send us a text Naim Alkhouri, Ian Rowe and GenFit Global Diagnostics Leader Suneil Hosmane join Louise Campbell and Roger Green to review presentations from Day Two at the 4th Global NASH Congress. On April 29, over 175 NASH stakeholders from across the globe met virtually to hear 20 presentations from leaders in academia and industry. SurfingNASH selected 9 presentations to discuss in a session recorded right after the conference concluded. When the five panelists got together, the di...

30 Apr 202142min

S2-E21 - Day One At The 4th Global NASH Congress -- Diagnostics, Drugs And Regulatory Issues

S2-E21 - Day One At The 4th Global NASH Congress -- Diagnostics, Drugs And Regulatory Issues

Send us a text Manal Abdelmalek, Jörn Schattenberg and GenFit Global Diagnostics Leader Suneil Hosmane join the Surfers to review presentations from Day One at the 4th Global NASH Congress. On April 28, over 175 NASH stakeholders from across the globe will meet virtually to hear 23 presentations from leaders in academia and industry. SurfingNASH has selected 11 presentations to discuss in a session we will record right after the conference concludes. The speakers and their broad topic areas ...

29 Apr 20211h 1min

S2-E20.3 - How Can we Best Use NASHmap in Clinical trials and Patient Treatment?

S2-E20.3 - How Can we Best Use NASHmap in Clinical trials and Patient Treatment?

Send us a text The Surfers explore the impact that NASHmap, the first Machine Learning model that can identify patients likely to have NASH, can have on clinical trials and patient treatment. Prof. Schattenberg and colleagues built the NASHmap model from a NIDDK database and validated it using the Optum de-identified EHR dataset. The model includes 14 variables, some obvious, others less so, that produce an AUC of 0.82 in the NIDDK database and 0.79 in the Optum database. This conversation e...

25 Apr 202115min

S2-E20.2 - What Can We Learn about NASH From NASHmap?

S2-E20.2 - What Can We Learn about NASH From NASHmap?

Send us a text The Surfers analyze outputs from NASHmap, the first Machine Learning model that can identify patients likely to have NASH, to learn what we can about the disease and how to think about its value for racial and ethnic minorities. Prof. Schattenberg and colleagues built the NASHmap model from a NIDDK database and validated it using the Optum de-identified EHR dataset. The model includes 14 variables, some obvious, others less so, that produce an AUC of 0.82 in the NIDDK database ...

24 Apr 202121min

S2-E20 - 14-variable Machine Learning model identifies Probable NASH patients from Electronic Health Records

S2-E20 - 14-variable Machine Learning model identifies Probable NASH patients from Electronic Health Records

Send us a text Jörn Schattenberg discusses NASHmap, the first Machine Learning model that can identify patients likely to have NASH in clinical settings. Louise, Roger and guest Dr. Kris Kowdley join Jörn to discuss the model from academic, patient treatment and statistical perspectives. Prof. Schattenberg and colleagues built the NASHmap model from a NIDDK database and validated it using the Optum de-identified EHR dataset. The model includes 14 variables, some obvious, others less so, that...

22 Apr 202153min

S2-E20.1 - How NASHmap, the 1st Machine Learning Model to Identify Probable NASH Patients, Came to Life

S2-E20.1 - How NASHmap, the 1st Machine Learning Model to Identify Probable NASH Patients, Came to Life

Send us a text Jörn Schattenberg discusses the issues that drove the project to develop a Machine Learning model that can identify patients likely to have NASH in clinical settings, and discusses key elements of study and model design. Prof. Schattenberg and colleagues built the NASHmap model from a NIDDK database and validated it using the Optum de-identified EHR dataset. The model includes 14 variables, some obvious, others less so, that produce an AUC of 0.82 in the NIDDK database and 0.7...

21 Apr 202112min

S2-E19.3 - Pharmacotherapy Themes At The 4th Global NASH Congress

S2-E19.3 - Pharmacotherapy Themes At The 4th Global NASH Congress

Send us a text Jörn Schattenberg and GenFit Global Diagnostics Leader Suneil Hosmane join the Surfers to review pharmacotherapy themes to be covered at the 4th Global NASH Congress. Keynote Speaker Suneil Hosmane joins Louise Campbell and Roger Green to form the coverage team for the 4th Global NASH Congress. In this conversation, Jörn Schattenberg joins them to review drug-related topics covered at the Congress. This conversation discusses issues ranging from modes of action that attack fru...

18 Apr 202112min

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