S6- E3.1 - Roundtable: Spotting Tomorrow’s Trends in Today's MASLD Studies

S6- E3.1 - Roundtable: Spotting Tomorrow’s Trends in Today's MASLD Studies

Send us a text Surfing the MASH Tsunami continues its coverage of the AASLD Emerging Trends Conference on MASLD, MetALD and ALD. This week, the panelists focus on what studies on bariatric surgery and drugs in development can tell us about future treatment and explore some clinical trial questions. Guest Surfers include Professor Aleksander Krag of the University of Southern Denmark, the current Secretary-General of EALS, hepatologist Alexander Lalos of Robert Wood Johnson hospital, and...

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S4 E50.2 - Wrapping Up 2023 - An Interview with Mike Betel and Tony Villiotti

S4 E50.2 - Wrapping Up 2023 - An Interview with Mike Betel and Tony Villiotti

Send us a text Surfing the MASH Tsunami continues its 2023 wrap-up conversations with patients and patient advocates Mike Betel of the Fatty Liver Alliance (Canada) and Tony Villiotti of NASH kNOWledge (Pittsburgh, PA), along with co-hosts Jörn Schattenberg and Roger Green. The conversation focuses on viewing the year's major events and upcoming priorities from a patient advocate's point of view. The conversation starts by looking at the roles that patient advocates in different countr...

22 Dec 202340min

S4 - E50.1 - Wrapping Up 2023 in Steatotic Liver Disease: A Discussion with Jeff Lazarus

S4 - E50.1 - Wrapping Up 2023 in Steatotic Liver Disease: A Discussion with Jeff Lazarus

Send us a text Surfing the MASH Tsunami kicks off its 2023 wrap-up conversations with Jeff Lazarus, the 2023 winner of the Distinguished Scientific Achievement Award from the American Liver Foundation. He discusses three core MASLD-related opportunities for which he played a key role in 2023: the Research in Action initiative, the new MASLD nomenclature process and the Healthy Livers, Healthy Lives coalition. Most of this discussion focuses on Jeff's work leading the Research in Action coalit...

20 Dec 202331min

S4-E49.6 - Conversations From The Vault -- NITs At TLM2022

S4-E49.6 - Conversations From The Vault -- NITs At TLM2022

Send us a text This Vault conversation stems from the wrap-up to TLM2022. In the episode, the panel (Jörn Schattenberg, William Alazawi, Naim Alkhouri, Laurent Castera, Ken Cusi, Wayne Eskridge and Roger Green) addresses several topics from the program. This one focuses largely on NITs. This conversation focuses on several papers of interest to Laurent. The first is a prospective screening study on patients with diabetes seen in either primary care or a diabetes clinic in the US. Using...

3 Dec 202316min

S4-E49.5 - TLM2023 Wrap-Up - Panel Discusses New Nomenclature, Impact Of Triple Agonists

S4-E49.5 - TLM2023 Wrap-Up - Panel Discusses New Nomenclature, Impact Of Triple Agonists

Send us a text This conversation between Scott Friedman, Laurent Castera, Louise Campbell and Roger Green covers a pivotal session on the new MASLD nomenclature, plus what the panelists found exciting and important about the developing class of triple agonists, at TLM 2023. This conversation starts with Roger stepping gently into the topic of the new MASLD nomenclature by discussing a Saturday morning session chaired by Maru Rinella and Meena Bansal. The session took a broad, fairly de...

3 Dec 202316min

S4-E49.4 - TLM2023 Wrap-Up - Panel Discusses Liver Science, Other Issues

S4-E49.4 - TLM2023 Wrap-Up - Panel Discusses Liver Science, Other Issues

Send us a text This conversation between Scott Friedman, Laurent Castera, Louise Campbell and Roger Green covers what the panelists found exciting, important or striking about liver science, VCTE, regulatory approvals using NITs or AI, and other issues at TLM 2023. It starts with Roger sharing his belief that regulators are likely to approve NITs only if a small battery of tests (or ideally, a single test) prove valuable in assessing all agents, or at least all agents, for a stage of d...

3 Dec 202315min

S4-E49.3 - TLM2023 Wrap-Up - Panel Discusses NITs, AI And Bariatric Surgery

S4-E49.3 - TLM2023 Wrap-Up - Panel Discusses NITs, AI And Bariatric Surgery

Send us a text This conversation between Scott Friedman, Laurent Castera, Louise Campbell and Roger Green covers what the panelists found exciting, important or striking about the presentations covering NITs, artificial intelligence and bariatric surgery at TLM2023. The conversation starts with Roger discussing a presentation in which Stephen Harrison shared HistoIndex data from the MAESTRO-NASH trial for resmetirom. HistoIndex’s proprietary methods produced results suggesting 34% impr...

3 Dec 202314min

S4-E49.2 - TLM2023 Wrap-Up - Panel Discusses Medicines

S4-E49.2 - TLM2023 Wrap-Up - Panel Discusses Medicines

Send us a text This conversation between Scott Friedman, Laurent Castera, Louise Campbell and Roger Green covers what the panelists found exciting, important or striking about the presentations of clinical trial results at TLM2023. Instead of focusing immediately on MASH drugs, Scott suggested we should not overlook the idea that elafibranor is preparing to come to market in the US as a novel medication for PBC with good efficacy and safety from patients who do not respond well to urs...

3 Dec 202312min

S4-E49.1 - TLM2023 Wrap-Up - Panel Discusses General Impressions

S4-E49.1 - TLM2023 Wrap-Up - Panel Discusses General Impressions

Send us a text This conversation between Scott Friedman, Laurent Castera, Louise Campbell and Roger Green covers the four panelists’ general impressions of TLM2023, both the good and bad of it. Scott starts with a simple statement: “It was good to be at an AASLD that felt like an AASLD. Specifically, Scott is talking about the energy and excitement associated with the meeting. He also approves of Boston as a meeting location. Scott’s meeting worst was the meeting app. The group el...

2 Dec 202310min

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