Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Moderator: Jean-Marc Burgunder (Guemligen, Switzerland)Guest: Sandrine Humbert (Paris, France)In this week's episode, Burgunder and Humbert discuss the intriguing phenomenon of somatic expansion—the further increase of CAG repeat numbers in the gene involved in Huntington’s disease, particularly in the striatum. They explore the molecular mechanisms behind this process, as addressed in two recent research papers.Please find here the papers discussed in this episode: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s diseaseand Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(209)

Ep. 209: From Gesture to Language: The Evolution of the Motor System-Language Interface

Ep. 209: From Gesture to Language: The Evolution of the Motor System-Language Interface

Moderator: Elka Stefanova (Belgrade, Serbia) Guest: Stefano Francesco Cappa (Milan, Italy) In this episode, Elka Stefanova speaks with Stefano Francesco Cappa about the relationship between languag...

12 Juli 28min

Ep. 208: Language: The Bridge Between a Noisy World and a Stable Mind

Ep. 208: Language: The Bridge Between a Noisy World and a Stable Mind

Moderator: Elisa Canu (Milan, Italy) Guest: Cornelius Weiller (Freiburg, Germany) In this episode, Elisa Canu speaks with Cornelius Weiller about the neural architecture underlying language, conce...

5 Juli 32min

Ep. 207: Pills to face burnout and the role of occupational health therapists

Ep. 207: Pills to face burnout and the role of occupational health therapists

Moderator: Gail Kinman (London, UK) Guest: Alice Accorroni (Geneva, Switzerland) In this episode, Alice Accorroni speaks with Gail Kinman about burnout in healthcare and the role of occupational h...

28 Juni 32min

Ep. 206: Genetics in ALS and frontotemporal dementia – from pathophysiology to treatment

Ep. 206: Genetics in ALS and frontotemporal dementia – from pathophysiology to treatment

Moderator: Cláudia Santos Silva (Lisbon, Portugal) Guest: Andrea Calvo (Turin, Italy) In this episode, Cláudia Santos Silva speaks with Andrea Calvo about the genetics of amyotrophic lateral scler...

21 Juni 19min

Ep. 205: Neurofilaments as Biomarkers in ALS and frontotemporal dementia: From Bench to Bedside

Ep. 205: Neurofilaments as Biomarkers in ALS and frontotemporal dementia: From Bench to Bedside

Moderator: Raffaele Dubbioso (Naples, Italy) Guest: Andrea Malaspina (London, UK) and Francesco Di Lorenzo (Rome, Italy) In this episode, Raffaele Dubbioso speaks with Andrea Malaspina and Frances...

14 Juni 34min

Ep. 204: Social Cognition in ALS – beyond motor neurons

Ep. 204: Social Cognition in ALS – beyond motor neurons

Moderator: Elisa Canu (Milan, Italy) Guest: Anna Gilioli (Milan, Italy) In this episode, Elisa Canu speaks with Anna Gilioli about social cognition impairment in amyotrophic lateral sclerosis (ALS...

7 Juni 12min

Ep. 203: Diagnostic challenges in ALS and frontotemporal dementia

Ep. 203: Diagnostic challenges in ALS and frontotemporal dementia

Moderator: Valentina Iuzzolino (Naples, Italy) Guest: Elka Stefanova (Belgrade, Serbia) and Mamede de Carvalho (Lisbon, Porugal) In this episode, Valentina Iuzzolino speaks with Elka Stefanova and...

31 Maj 27min

Ep. 202: Clinical neurology Meets AI: Are we prepared?

Ep. 202: Clinical neurology Meets AI: Are we prepared?

Moderator: Raphael Wurm (Vienna, Austria) Guest: Roland Wiest (Bern, Switzerland) In this episode, Raphael Wurm speaks with Roland Wiest about how the AI revolution is set to reshape the clinical ...

24 Maj 26min

Populärt inom Vetenskap

p3-dystopia
dumma-manniskor
allt-du-velat-veta
bildningspodden
kvalificerat-hemligt-poddradio
svd-nyhetsartiklar
rss-vetenskapsradion-2
det-morka-psyket
sexet
rss-ufobortom-rimligt-tvivel
rss-vetenskapsradion
medicinvetarna
rss-spraket
paranormalt-med-caroline-giertz
vetenskapsradion
rss-kriminologerna
rss-arkeologi-historia-podden-som-graver-i-vart-kulturlandskap
rss-broccolipodden-en-podcast-som-inte-handlar-om-broccoli
hacka-livet
barnpsykologerna