From bats to cancer – the power of gene regulation

From bats to cancer – the power of gene regulation

Join us for an insightful conversation with Dr. Nadav Ahituv, a leader in human genetics and gene regulation at UCSF. He shares his personal journey from scoliosis patient to genetic researcher, exploring the mysteries of non-coding DNA, massively parallel reporter assays, and CRISPR-based therapeutic innovations.

We dive into his lab’s diverse projects, from decoding bat wing development and diet adaptation to tackling complex diseases like scoliosis and cancer through gene modulation. Learn how cloning is used alongside technologies like AI, genome-wide sequencing, and CRISPR to revolutionize our understanding of regulatory elements and shape the future of precision medicine.

Plus, discover how a surprising approach—using modified fat cells—could be a game-changer in cancer therapy. This episode is a must-listen for anyone fascinated by the intersection of genetics, technology, and evolution.

Subscribe to get future episodes as they drop and if you like what you’re hearing we hope you’ll share a review or recommend the series to a colleague. 

Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology.

For Research Use Only. Not for use in diagnostic procedures.

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Avsnitt(54)

The tools, stories, and science behind Absolute Gene-ius

The tools, stories, and science behind Absolute Gene-ius

Molecular biology is more than a set of techniques. It is a toolkit for asking better questions. In this special crossover episode of Speaking of Mol Bio, Steve Lewis welcomes Jordan Ruggieri, Senior ...

8 Juli 26min

CRISPR, MPRA, and the genetics of mental health

CRISPR, MPRA, and the genetics of mental health

Some genetic variants may help explain why different psychiatric disorders share overlapping biology. In this episode of Speaking of Mol Bio, host Steve Lewis speaks with Jess McAfee, PhD, and Alejand...

24 Juni 30min

From prototype to production – solving the scale-up gap

From prototype to production – solving the scale-up gap

Great science doesn’t always translate into a scalable product, and that gap can stall even the most promising innovations. In this Mol Bio Minutes episode, Steve Lewis explores a common challenge in ...

10 Juni 7min

The real cost of PCR - beyond price per reaction

The real cost of PCR - beyond price per reaction

Not all experiments are created equal, and neither are the decisions behind them. In this episode, Cam Cyr explores how scientists navigate the balance between cost and performance in molecular biolog...

27 Maj 30min

The molecular toolkit behind HIV research

The molecular toolkit behind HIV research

HIV research is one of the clearest examples of molecular biology in action. In this Mol Bio Minutes episode, Dr. Ryan Jeep walks through how fundamental molecular techniques power everything from det...

13 Maj 14min

DNA-encoded library use in living cells for drug discovery

DNA-encoded library use in living cells for drug discovery

In this episode of Speaking of Mol Bio, host Steve Lewis speaks with Dr. Leif Larsen, Director of Biology at Vipergen, about the power of DNA-encoded libraries (DELs) in modern drug discovery. DEL tec...

22 Apr 30min

Choosing the right PCR method for your experiment

Choosing the right PCR method for your experiment

In this Mol Bio Minutes mini-episode of Speaking of Mol Bio, Dr. Andrea Hunger walks listeners through the practical differences between three core PCR approaches: endpoint PCR, quantitative PCR (qPCR...

8 Apr 13min

From bench to bushland ─ developing a koala chlamydia vaccine

From bench to bushland ─ developing a koala chlamydia vaccine

In this Season 4 premiere of Speaking of Mol Bio, host Steve Lewis speaks with Dr. Nina Pollak from the University of the Sunshine Coast about the development of a single-dose vaccine aimed at protect...

25 Mars 36min

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