S6 - E5.3 - Expert: Scott Friedman on Gene Therapy and Advances in Liver Science

Send us a text This week's Vault looks back to the EASL Congress 2023 and includes Aleksander Krag, Sven Francque and all three surfers: Jörn Schattenberg, Louise Campbell and Roger Green. The focus of this conversation revolves around program design. The original conversation came with a robust description: This conversation starts with Roger’s question to Sven around his role as Educational Councillor and the various educational opportunities embedded within the program. Sven first descri...

2 Juni 202417min

Send us a text This final conversation from SurfingMASH's EASL Congress 2024 preview includes two final papers, one covering MASLD drug development, and a diverse set of answers to Roger Green's closing question. Jörn Schattenberg discusses a paper he will present on a completely new concept to treat MASLD, a Phase 2a trial of a transglutaminase inhibitor, a compound originally developed for Celiac disease. Aleksander Krag describes as "exciting" the idea that this concept came from Celiac ...

2 Juni 202412min

Send us a text This conversation revolves largely around two Big Data presentations Hannes Hagstrom's team is sharing at the EASL Congress. Every other panelist has at least one meaningful comment to make about the future of Big Data in MASLD. Hannes describes two big data studies of his own, "very much Big Data, but it's not omics." One examined 860,000 residents of Stockholm who took a liver test between 2010-2022 seeking to estimate liver and cardiovascular risk. It relied on a tool from ...

2 Juni 202412min

Send us a text This conversation starts with Jörn Schattenberg joining the conversation. The main points are two abstracts, one reviewed by Jörn and the other by Aleksander Krag. As Hannes finishes discussing his abstract, Jörn joins the podcast. While Michelle looks for an abstract she highlighted on which Jörn is an author, Jörn discusses a panel that Hannes will chair on the future of hepatology, at which Jörn will speak about artificial intelligence. Hannes shares his excitement about a...

1 Juni 202413min

Send us a text This conversation starts and ends with thoughts from Michelle Long. Her first comment praises the expanded networking opportunities in the program, and her last comment focuses on the quality of the MASLD abstracts (really, all abstracts) and the importance of reviewing them in advance. Michelle starts by commenting on the networking sessions that EASL is sponsoring around the large consortia and other projects. "It really speaks to how... open this community is to explo...

1 Juni 202412min

Send us a text This first conversation from our EASL Congress 2024 preview starts with EASL Secretary General Aleksander Krag offering his vision for next week's meeting in Milano, after which Hannes Hagstrom shares some of his thoughts about the meeting design. Aleksander starts by discussing the preparation that has gone into this Congress since the Vienna meeting closed last August. The goals are ambitious, but he feels EASL has, by and large, succeeded. Aleksander mentions that 7,0...

1 Juni 202413min

Send us a text Next week, 7,000+ hepatology stakeholders will convene in Milano, Italy, to consume 2,000+ posters and presentations, including an extensive set of MASLD studies, at EASL Congress 2024. EASL Secretary General Aleksander Krag, Hannes Hagstrom, and Michelle Long join Jörn Schattenberg and Roger Green to preview the program. 00:00:00 - Surf's Up: Season 5 Episode 17 Standard lead-in, including quotes from panelists. 00:02:40 - Introduction Roger describes the structure of this e...

30 Maj 202459min

Send us a text In this excerpt from last July, Stephen Harrison shares results of the FASCINATE-2 study as part of SurfingMASH's larger coverage of exciting drug trials presented at The EASL Congress. The original writeup reads: This month, Surfing NASH embarks on a series of episodes dedicated to takeaways emerging from June's two major conferences: the 2023 EASL Congress in Vienna and the American Diabetes Association's 83rd Scientific Sessions meeting in San Diego. This is the secon...

26 Maj 202411min