S6 - E5.3 - Expert: Scott Friedman on Gene Therapy and Advances in Liver Science

S6 - E5.3 - Expert: Scott Friedman on Gene Therapy and Advances in Liver Science

Send us a text This week’s expert, Hepatologist and Key Opinion Leader Scott Friedman, joins Roger to discuss advances in acceptance of gene therapy and knowledge in other areas of basic liver science. When discussing science, he pays particular attention to findings on the diversity of stellate cells and his interest in CAR-T as a therapy for liver disease. This conversation starts with Scott discussing gene therapy. Specifically, he applauds the idea that gene therapy is becoming acce...

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S5 - E25 - Reviewing Expert Recommendations on the Use of Resmetirom

S5 - E25 - Reviewing Expert Recommendations on the Use of Resmetirom

Send us a text 00:00:00 - Surf's Up: Season 5 Episode 25 On July 20, Clinical Gastroenterology and Hepatology released the paper, Expert Panel Recommendations: Practical Clinical Applications for Initiating and Monitoring Resmetirom in Patients with MASH/NASH and Moderate to non-cirrhotic Advanced Fibrosis. Corresponding author Maru Rinella joins the Surfers to share key points from the recommendations and offer her thoughts on what lay behind them. 00:02:26 - Introduction and Groundbreaker...

9 Aug 202442min

S4 - E24.5 - SurfingMASH Question of The Week: Keys to Improving Provider-Patient Communication

S4 - E24.5 - SurfingMASH Question of The Week: Keys to Improving Provider-Patient Communication

Send us a text Two weeks ago, the SurfingMASH Question of the Week asked, "What structural or educational changes do you anticipate will significantly improve Provider-Patient communication? Will these changes require more from the provider and more from the patient?" Today, S5 E23 panelists Mike Betel and José Willemse join Roger Green to review the three answers we received. Of the three questions from audience members, one from a patient/patient advocate suggested greater honesty, b...

8 Aug 202420min

S5 - E24.4 - EASL Congress Six Weeks Later: Jeff McIntyre's Key Implications for GLI

S5 - E24.4 - EASL Congress Six Weeks Later: Jeff McIntyre's Key Implications for GLI

Send us a text In the second half of Roger Green's interview with Global Liver Institute Vice President, Liver Programs Jeff McIntyre, Jeff discusses the implications of his key EASL Congress takeaways for GLI and other patient advocacy groups. To Jeff, this trend makes patient advocates a more valuable player in the clinical trial design process, particularly when coupled with the FDA's increasing focus on diversity in trial populations. This will become particularly important becaus...

8 Aug 202418min

S5 - E24.3 - EASL Congress Six Weeks Later: Jeff McIntyre's Key Takeaways

S5 - E24.3 - EASL Congress Six Weeks Later: Jeff McIntyre's Key Takeaways

Send us a text This conversation contains the first half of Roger Green's interview with Global Liver Institute Vice President, Liver Programs Jeff McIntyre, during which the two discuss what Jeff considered the key strategic takeaways for GLI from the various EASL Congress presentations, abstracts and discussions. Jeff focuses on the "overriding sense of optimism" coming from the multiple pieces of positive drug data. He cites the data on Boehringer Ingelheim's survodutide, the follow...

7 Aug 202412min

S5 - E24.2 - EASL Congress Six Weeks Later: Mathieu Petitjean's Key Implications

S5 - E24.2 - EASL Congress Six Weeks Later: Mathieu Petitjean's Key Implications

Send us a text In the second half of Roger Green's interview with PharmaNest Founder and CEO Mathieu Petitjean, Matt discusses the implications of his key EASL Congress takeaways for PharmaNest. Matt starts this discussion with a simple question: Will biopsy-based analyses become part of a surrogate endpoint? As he points out, they are not today, and creating the necessary data might require a significant effort. If not, they are unlikely to remain relevant to the large, Phase 3 trial...

7 Aug 202410min

S5 - E24.1 - EASL Congress Six Weeks Later: Mathieu Petitjean's Key Takeaways

S5 - E24.1 - EASL Congress Six Weeks Later: Mathieu Petitjean's Key Takeaways

Send us a text This conversation contains the first half of Roger Green's interview with PharmaNest Founder and CEO Mathieu Petitjean. After Matt tells the audience a little about his background and PhramaNest, the two discuss what Matt considered the key strategic takeaways for PharmaNest from the various EASL Congress presentations, abstracts and discussions. Before answering the question, Matt describes the core services his company offers: "PharmaNest specializes in digital patholo...

7 Aug 202417min

S5 - E24 - A view of MASLD: Looking back at EASL Congress from six weeks later

S5 - E24 - A view of MASLD: Looking back at EASL Congress from six weeks later

Send us a text 00:00:00 - Surf's Up: Season 5 Episode 24 This week's episode on MASLD lessons from the EASL Congress 2024 includes three separate elements: individual interviews with PharmaNext Founder and CEO Mathieu Petitjean and Global Liver Institute Vice President of Liver Programs Jeff McIntyre, followed by a discussion with patient advocates Mike Betel of the Fatty Liver Alliance and José Willemse from the Netherlands, now supporting EASL. 00:02:45 - Introduction Rog...

3 Aug 20241h 16min

S5 SPECIAL 5 - Reviewing EASL Congress: Louise Campbell 3 (first-time material)

S5 SPECIAL 5 - Reviewing EASL Congress: Louise Campbell 3 (first-time material)

Send us a text This week, Surfing the MASH Tsunami looks back on interviews Roger Green conducted during the EASL Congress itself. This conversation with SurfingMASH co-host and Tawazun Health Founder and Clinical Director Louise Campbell took place on the last day of the Congress This portion of the conversation was not included in the original S5 E19 but instead was reserved for a special conversation at a later time (now). The specific focus of this conversation is on how practice pattern...

21 Juli 20249min

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