What Super Agers Reveal About Preventing Disease
The a16z Show14 Maj 2025

What Super Agers Reveal About Preventing Disease

American healthcare is in crisis—but what if we could change the system by preventing disease before it starts?

In this episode of the a16z Podcast, general partner Vijay Pande sits down with Dr. Eric Topol, founder and director of the Scripps Research Translational Institute and one of the most cited researchers in medicine, to explore the cutting edge of preventive healthcare and longevity science.

Drawing from his new book Super Agers: An Evidence-Based Path to Longevity, Topol breaks down why understanding the biology of aging—not reversing it—is the key to preventing the “Big Three” age-related diseases: cancer, cardiovascular disease, and neurodegenerative conditions. The conversation spans AI-powered risk prediction, organ clocks, polygenic risk scores, GLP-1s, and the cultural and economic shifts required to move from a “sick care” system to one rooted in precision prevention and extended healthspan.

If you’ve ever wondered how data, personalized medicine, and AI can add seven healthy years to your life—and what it will take to bring those benefits to everyone—this episode is for you.

Resources:

Find Eric on X: https://x.com/erictopol

Find Vijay on X: https://x.com/vijaypande

Stay Updated:

Let us know what you think: https://ratethispodcast.com/a16z

Find a16z on Twitter: https://twitter.com/a16z

Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Stay Updated:

Find a16z on YouTube: YouTube

Find a16z on X

Find a16z on LinkedIn

Listen to the a16z Show on Spotify

Listen to the a16z Show on Apple Podcasts

Follow our host: https://twitter.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.


Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Avsnitt(1000)

Creativity vs Control: Where AI Fits in the Creative Toolbox

Creativity vs Control: Where AI Fits in the Creative Toolbox

Being a creator in 2025 is tough—but building for creators is even harder. Perhaps no one understands this conundrum better than Scott Belsky. As the founder of Behance, a longtime executive at Adobe,...

25 Feb 202542min

Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto

Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto

Technology doesn’t grow in isolation—it evolves in waves. Just as mobile, cloud, and SaaS shaped the internet of the past 20 years, so too could crypto, AI, and new hardware usher in an era of the int...

20 Feb 202532min

The Critical Technology in Finding Critical Materials

The Critical Technology in Finding Critical Materials

Critical materials like copper, lithium, and gallium have been mined for decades, but their role in core technologies, geopolitics, and the energy transition have come to a height in recent years.In t...

11 Feb 202542min

DeepSeek: America’s Sputnik Moment for AI?

DeepSeek: America’s Sputnik Moment for AI?

Two words have caught the Internet by storm. DeepSeek. The Chinese reasoning model r1 is rivaling others at the frontier with an open-source MIT license, methods that some claim may be 45x more effici...

6 Feb 202543min

Ben Horowitz Sharing History with Dr. Clarence Jones, MLK's Speechwriter

Ben Horowitz Sharing History with Dr. Clarence Jones, MLK's Speechwriter

This week, a16z cofounder Ben Horowitz had a rare and invaluable conversation with Dr. Clarence B. Jones, a pivotal figure in American history. Dr. Jones, who served as speechwriter, attorney, and adv...

1 Feb 202555min

How AI Is Changing Warfare with Brian Schimpf, CEO of Anduril

How AI Is Changing Warfare with Brian Schimpf, CEO of Anduril

How is AI reshaping modern warfare? Speaking with a16z Growth General Partner David George, Anduril cofounder and CEO Brian Schimpf discusses how AI helps humans make better strategic decisions by sor...

28 Jan 202535min

RIP to RPA: How AI Makes Operations Work

RIP to RPA: How AI Makes Operations Work

Intelligent automation is transforming industries by tackling messy, unstructured workflows that traditional Robotic Process Automation (RPA) couldn’t handle. In this episode, a16z partner Kimberly Ta...

22 Jan 202517min

Marc Andreessen: Can Tech Finally Fix Healthcare?

Marc Andreessen: Can Tech Finally Fix Healthcare?

Healthcare is a $4 trillion industry, making up nearly a fifth of the U.S. economy—but despite having some of the best doctors and advanced technology, the system often delivers poor outcomes at skyro...

15 Jan 202532min

Populärt inom Business & ekonomi

badfluence
framgangspodden
varvet
rss-jossan-nina
uppgang-och-fall
rss-borsens-finest
avanzapodden
fill-or-kill
svd-tech-brief
rss-inga-dumma-fragor-om-pengar
dynastin
rss-svart-marknad
bathina-en-podcast
lastbilspodden
borsmorgon
rss-kort-lang-analyspodden-fran-di
montrosepodden
24fragor
kapitalet-en-podd-om-ekonomi
rss-dagen-med-di