How Alcohol Rewires Your Brain and Increases Cancer Risk by 40%! The Alcohol Doctor, Dr. Sarah Wakeman

How Alcohol Rewires Your Brain and Increases Cancer Risk by 40%! The Alcohol Doctor, Dr. Sarah Wakeman

Are you unknowingly damaging your brain and raising your cancer risk with just one drink? Discover the alarming truth about alcohol from Dr. Sarah Wakeman, what every adult needs to know now. Dr. Sarah Wakeman is senior medical director for substance use disorder at Mass General Brigham healthcare system, the number one research system in the U.S. She is also the Medical Director of the Mass General Hospital Addiction Consult Team and Assistant Professor of Medicine at Harvard Medical School. She explains: How alcohol is hijacking your dopamine system. Why no amount of alcohol is good for your brain. The shocking truth about moderate drinking. How doctors are failing addiction patients on a daily basis. Why 1 in 3 people will struggle with alcohol. 00:00 Intro 02:23 Sarah's Mission 02:52 Sarah's Education and Experience 03:40 Issues With Addiction Treatment in the Modern World 04:31 What Is Addiction? 05:48 What Things Are Capable of Being Addictive? 06:47 Physiological Dependence vs. Addiction 07:25 Scale of the Problem: Why Should People Care? 08:59 Is Society Getting Better or More Addicted? 09:32 Substance-Related Deaths During the Pandemic 10:22 What Drives People to Use Substances? 12:24 Substances' Effects on the Brain 14:29 Does Trauma at a Young Age Increase Addiction Risk? 16:36 The Opposite of Addiction Is Connection 18:11 Why Addiction Matters to Sarah 19:02 Living With a Family Member Struggling With Addiction 20:43 Who Is Sarah Trying to Save? 22:57 Change Happens When the Pain of Staying the Same Is Greater Than the Pain of Change 25:53 Misconceptions About Alcohol 28:15 Is There a Healthy Level of Alcohol Consumption? 28:50 Is One Drink a Day Safe for Health? 30:38 Link Between Moderate Drinking and Cancer 33:23 Types of Cancer Linked to Alcohol Consumption 34:51 Cancer Risk Among Heavy Drinkers 35:31 Heavy Drinking and Comorbidities as Cancer Risk Factors 36:20 How Alcohol Drives Cancer Mechanisms 38:00 Alcohol and Weight Gain 38:54 The Role of the Liver 42:07 Liver's Ability to Regenerate 46:37 How Alcohol Causes Brain Deterioration 47:23 Other Organs Affected by Alcohol 48:00 Alcohol's Impact on the Heart 49:08 Body Fat Percentage and Alcohol Tolerance 50:05 Does High Alcohol Tolerance Prevent Organ Damage? 50:46 What Is a Hangover? 52:14 Balancing the Risks and Benefits of Alcohol 53:47 Is Rehab Effective for Addiction? 56:50 Psychedelic Therapy for Addiction 57:36 GLP-1 Medications for Addiction Treatment 59:03 Ads 59:59 Celebrity Addictions 1:02:24 Stigma Around Addiction 1:04:41 Addiction Cases That Broke Sarah's Heart 1:12:43 Is Empathy Positive Reinforcement for Addicted Individuals? 1:15:34 Setting Boundaries With an Addicted Person 1:18:57 Motivational Interviewing to Support Recovery 1:22:19 Finding Motivation for Positive Change 1:26:03 Habits to Support Addiction Recovery 1:29:12 Ads 1:30:18 Can the Brain Recover From Addiction? 1:34:55 Unexpected Sources of Addictive Behavior 1:35:35 How Sarah Copes With Difficult Addiction Cases 1:37:10 Importance of Language Around Addiction 1:41:40 How Labels Limit People's Potential 1:46:05 Sarah's Upcoming Book You can find out more about Dr. Sarah’s profile, here: https://bit.ly/4mxu191 Ready to think like a CEO? Gain access to the 100 CEOs newsletter here: ⁠bit.ly/100-ceos-megaphone⁠ The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb Get email updates: https://bit.ly/diary-of-a-ceo-yt Follow Steven: https://g2ul0.app.link/gnGqL4IsKKb Research document: https://stevenbartlett.com/wp-content/uploads/2025/05/DOAC-Dr-Sarah-Wakeman-Independent-Research-further-reading.pdf Sponsors: Ekster - https://partner.ekster.com/DIARYOFACEO with code DOACLinkedin Ads - https://www.linkedin.com/DIARY Learn more about your ad choices. Visit megaphone.fm/adchoices

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E20: Deliciously Ella - Blogging Saved My Life

E20: Deliciously Ella - Blogging Saved My Life

What a chapter this is, I meet food writer and entrepreneur Ella Mills, more famously known under the brand Deliciously Ella. Ella tells her fascinating story, about how she fell very ill during university, battling with both her physical and mental health and describes how the blog she founded in 2012 not only launched her career, but saved her life. Learn more about your ad choices. Visit megaphone.fm/adchoices

18 Juni 201841min

E19: Luke Massie - I Have Nothing To Hide

E19: Luke Massie - I Have Nothing To Hide

In this chapter I had the privilege of sitting down with Luke Massie, owner and founder of Vibe tickets. Luke has recently been swarmed with bad press due to his business declaring bankruptcy, to which he then chose to buy back him self. I sat down with Luke to hear his side of the story and to ask him why he thinks he's being attacked for his business decisions. Learn more about your ad choices. Visit megaphone.fm/adchoices

11 Juni 20181h 14min

E18: Chris 'Drama' Pfaff - Dealing with Fame, Anxiety and Addiction

E18: Chris 'Drama' Pfaff - Dealing with Fame, Anxiety and Addiction

In Chapter Eighteen I'm honoured to invite Drama aka Chris Pfaff, founder of the internationally renowned Young & Reckless streetwear brand. After creating a fashion powerhouse with no prior business experience or a college education, I wanted to find out what drives him and the lessons he's learnt along the way. We discuss the struggles of being an entrepreneur, the pressures of being a reality tv star and his addiction to alcohol and Xanax. Learn more about your ad choices. Visit megaphone.fm/adchoices

4 Juni 20181h 4min

E17: Marriage, Mental Health, Masturbation

E17: Marriage, Mental Health, Masturbation

Damn, it's been a long time, this the first episode on my new US journey. In this chapter I explain why an elderly couple made me jealous, debunk a common myth around visualisation and discuss marriage, mental health and masturbation. What a weird ending. Learn more about your ad choices. Visit megaphone.fm/adchoices

27 Maj 201832min

E16: I Am Jealous Of Death

E16: I Am Jealous Of Death

This is my favourite episode I've recorded alone. In this chapter I discuss the goals and dangers of moving to New York, explain the reason why I'm jealous of death, an unpredicted problem this week almost cost the business millions and of course, no episode would be complete without a development in my relationship status. Learn more about your ad choices. Visit megaphone.fm/adchoices

22 Apr 201834min

E15: Gerard Adams - A $50m Elite Exit

E15: Gerard Adams - A $50m Elite Exit

In this Chapter, I meet Gerard Adams - A born entrepreneur. He takes us through his journey of struggle, success & tough decisions as he grew one of the most popular online publishers - Elite daily, through to it's sale to the Daily Mail. Now heading up an incubator for entrepreneurs in Fownders, Gerard's mission is bigger than ever. Learn more about your ad choices. Visit megaphone.fm/adchoices

16 Apr 201841min

E14: John Vincent - Building A Restaurant Empire

E14: John Vincent - Building A Restaurant Empire

In Chapter Fourteen, I'm honoured to invite John Vincent, Co-Founder of hugely popular healthy eating fast food chain Leon. Having built an empire of 52 restaurants, I wanted to find out what drives him and the lessons he's learnt along the way. Tragically, John's father passed away a week prior to our conversation, and he discusses what his fathers influence has taught him. Learn more about your ad choices. Visit megaphone.fm/adchoices

9 Apr 201852min

E13: Why We're All F*cked Up

E13: Why We're All F*cked Up

In this chapter, I discuss the importance I've learnt this past week in first impressions, the reason why we're ALL f*cked up and how we can use that to our advantage, the 20 reasons why you shouldn't be an entrepreneur, and I update on my new journey in moving to New York and as always, my relationship status.. Learn more about your ad choices. Visit megaphone.fm/adchoices

19 Mars 201848min

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