Do SSRIs Really Work? Depression Treatment and the Serotonin Debate with Dr Ferghal Armstrong

Do SSRIs Really Work? Depression Treatment and the Serotonin Debate with Dr Ferghal Armstrong

Do SSRIs Really Work? Understanding Depression Treatment and the Serotonin Debate.Are you wondering how SSRIs work for depression treatment or if they’re right for your mental health? Join Dr. Ferghal Armstrong on Cracking Addiction for a myth-busting dive into selective serotonin reuptake inhibitors, the cornerstone antidepressants for mood disorders like severe depression, mild depression, and moderate depression. This episode unpacks the science behind SSRIs, from the chemical imbalance theory of serotonin to the modern role of neuroplasticity in reshaping brain pathways.Dr. Armstrong explains what do SSRIs do, revealing why antidepressant efficacy isn’t instant—those crucial 4-8 weeks are about brain adaptation, not just a serotonin boost. He breaks down clinical trials, showing where SSRIs outperform the placebo effect and where they fall short, especially for mild depression. With antidepressant controversy swirling, learn why side effects like lethargy or emotional numbness affect many, and why only about half of patients see success, highlighting the need for personalized medicine.This video is essential for anyone navigating depression treatment, supporting loved ones, or prescribing antidepressants as clinicians. Dr. Armstrong explores how therapy options and the therapeutic setting amplify results, while the placebo effect can rival SSRIs in some cases. He tackles real-world challenges, from varying response rates to the push for mental health awareness in choosing the right path.Don’t miss this honest look at SSRIs—their strengths, limits, and role in mental health. Dr. Armstrong’s evidence-based insights from clinical trials empower you to make informed decisions about mood disorders and therapy options. Hit play for trustworthy answers and a fresh perspective on the antidepressant controversy!Chapters00:00:00 Introduction: SSRIs and the Mystery of How They Work00:00:41 How SSRIs Affect Serotonin in the Brain00:01:19 Challenging the Chemical Imbalance Theory00:02:09 Do SSRIs Actually Work? Examining the Evidence00:02:53 The Placebo Effect and Study Limitations00:03:31 Real World Response Rates and What They Mean00:04:05 Clinical Judgment and Finding the Right Treatment00:04:44 Setting Realistic Expectations: SSRIs Are Not Magic Bullets00:05:11 Conclusion: The Evolving Science and Role of SSRIs in Depression

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Opioid use disorder and pregnancy

Opioid use disorder and pregnancy

Episode 18 of Cracking Addiction explores the management of opioid use disorder in pregnancy.Most women presenting with opioid dependence are of child-bearing age with chaotic drug use predisposes to amenorrhoea. The initiation of opioid substitution therapy (OST) facilitates stability and reinstatement of regular menstrual cycles and thus OST is a risk factor for unplanned pregnancy. About Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses availablehttps://www.meducate.com.au

1 Dec 202117min

Drugs of Concern

Drugs of Concern

Episode 17 of Cracking Addiction explores the range of drugs one can become dependent upon or addicted to and how to identify someone at risk of prescription drug aberrancy.About Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses availablehttps://www.meducate.com.au

24 Nov 202121min

How to take an accurate substance use history

How to take an accurate substance use history

How to take an accurate substance use history.Taking an accurate substance use history is of great importance in the management of addiction. There are a number of strategies that one could use but the most important part of history taking is that of demeanour and empathy. The best results and most accurate information are often obtained when one treats one’s patients with human empathy and in a non-judgemental manner. About Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses availablehttps://www.meducate.com.au

17 Nov 202115min

Methadone and it’s social benefits

Methadone and it’s social benefits

Cracking Addiction explores the social and societal benefits of Methadone. Methadone has a number of benefits that extend from not only the person taking it but also society as a whole. Methadone decreases criminality with the overall reduction in convictions and cautions estimated to be at 10% for each six months enrolled in methadone maintenance therapy with patients in continuous treatment receiving the best outcomes.

10 Nov 202115min

Methadone in Opioid Agonist Therapy

Methadone in Opioid Agonist Therapy

Ferghal & Thileepan explore the role of Methadone in opioid agonist therapy.

3 Nov 202113min

Opioid Replacement Therapy Part 1

Opioid Replacement Therapy Part 1

Episode 13 of Cracking Addiction covers opioid replacement therapy (ORT) and the philosophy and evidence behind this highly effective treatment for patients with opioid use disorder.

26 Okt 202119min

Dependence, Addiction and Opioid Use Disorder

Dependence, Addiction and Opioid Use Disorder

In this episode of Cracking Addiction we cover the difference between dependence and addiction, the intricacies of addiction and provide a definition of opioid use disorder

20 Okt 202113min

OPQRST

OPQRST

Cracking Addiction covers the OPQRST framework and how to use this framework to prescribe safely to patients on opioid medications.

13 Okt 202118min

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