Ep 50 Antibiotics: We owe it all to chemistry!

Ep 50 Antibiotics: We owe it all to chemistry!

Fifty episodes. That’s fifty (sometimes) deadly viruses, bacteria, protozoa, parasites, and poisons. And don’t forget the fifty quarantinis to accompany each! What better way to celebrate this momentous occasion than talking about something that may actually save you: antibiotics. In this, our golden anniversary episode, our ambition tempts us to tackle the massive world of these bacteria-fighting drugs. We explore the various ways that antibiotics duel with their bacterial enemies to deliver us from infection, and we trace their history, from the early years of Fleming and Florey to the drama-laden labs of some soil microbiologists. Finally, we end, as we always do, with discussing where we stand with antibiotics today. Dr. Jonathan Stokes (@ItsJonStokes), postdoctoral fellow in Dr. Jim Collins’ lab at MIT, joins us to talk about some of his lab’s amazing research on using machine learning to discover new antibiotics, which prompts us to repeat “that is SO COOL” and “we are truly living in the future.” We think you’ll agree.

To read more about using machine learning to uncover antibiotic compounds, head to the Collins’ lab website, the Audacious Project site, or check out Dr. Stokes’ paper:

Stokes, Jonathan M., et al. "A deep learning approach to antibiotic discovery." Cell 180.4 (2020): 688-702.

See omnystudio.com/listener for privacy information.

Avsnitt(282)

From the Vault - Endometriosis: Menstrual Backwash (Ep 88)

From the Vault - Endometriosis: Menstrual Backwash (Ep 88)

This episode originally aired on January 11th, 2022. Chances are you know someone with endometriosis, or perhaps you’re affected yourself. But despite its incredibly high prevalence, endo remains almo...

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From the Vault - Hepatitis B: Hepatiti, Take 2 (Ep 89)

From the Vault - Hepatitis B: Hepatiti, Take 2 (Ep 89)

This episode originally aired on January 25th, 2022. In light of the recent changes by RFK jr’s Advisory Committee on Immunization Practices (ACIP) to eliminate the universal birth dose of the hepatit...

23 Dec 20251h 30min

Ep 196 Health Myths: Fact or fiction?

Ep 196 Health Myths: Fact or fiction?

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Special Episode: Dr. Homer Venters & Outbreak Behind Bars

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Ep 195 Salt Part 2: The Substance

Ep 195 Salt Part 2: The Substance

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Ep 194 Salt Part 1: The Seasoning

Ep 194 Salt Part 1: The Seasoning

Have you ever thrown a pinch of spilled salt over your left shoulder? Or said to someone “well, take his opinion with a grain of salt”? Or looked up the potential salary of a job listing? Salt is so d...

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Special Episode: Gabriel Weston & Alive

Special Episode: Gabriel Weston & Alive

In an anatomy and physiology class, you may learn how the different heart valves work to circulate your blood, how the structure of your kidney helps to maintain electrolyte levels, and how the expans...

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Ep 193 Necrotizing Fasciitis: A strange beast

Ep 193 Necrotizing Fasciitis: A strange beast

If you were asked to describe necrotizing fasciitis in three words, you might choose: rapid, deadly, and rare. The third of those adjectives may provide some comfort, but the first two are the clear i...

11 Nov 20251h 7min

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