Ep 90 Human African Trypanosomiasis: A lot to unpack

Ep 90 Human African Trypanosomiasis: A lot to unpack

Here on the podcast, we’re no strangers to multi-host parasites with complicated life cycles, intricate ecologies and dense human histories. But human African trypanosomiasis (HAT) might require the most unpacking yet. In this episode, we do a deep dive into the tsetse fly-transmitted HAT, whose other name, sleeping sickness, doesn’t quite capture just how deadly this parasitic infection can be. First, we ask how these two trypanosomes cause the signs and symptoms they do, especially the strange sleep disruptions that gave this neglected tropical disease one of its names. Then, after a brief detour discussing the fascinating ability of tsetse flies to give live birth, we explore the many political and ecological factors that set the stage for the devastating HAT epidemics of the early 20th century. We wrap up the episode with a look at the current global status of HAT, and with new, effective, and easy-to-administer drugs on the scene along with a downward trend in cases, we’re certainly hopeful for the future elimination of this disease.

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Avsnitt(292)

Ep 214 Boogers: Digging for treasure

Ep 214 Boogers: Digging for treasure

Hard and crusty. Green and gloopy. Clear and watery. Boogers come in a veritable rainbow of colors and a full spectrum of textures from liquid to solid. They’re really quite impressive if you think ab...

30 Juni 1h 2min

Special Episode: Dr. Carl Elliott & The Occasional Human Sacrifice

Special Episode: Dr. Carl Elliott & The Occasional Human Sacrifice

Stories of unethical medical experimentation often center around the individuals who spearheaded such atrocities or highlight how patient protection laws were changed in response to the studies. But r...

23 Juni 57min

Ep 213 Burns Part 2: It’s like sci-fi but real 

Ep 213 Burns Part 2: It’s like sci-fi but real 

At the turn of the 20th century, a severe burn was often a death sentence. Today, that is no longer the case. Over the past eighty years, burn care has undergone a profound transformation thanks to cr...

16 Juni 58min

Ep 212 Burns Part 1: The first million or so years

Ep 212 Burns Part 1: The first million or so years

Burns have been a part of the human experience since our hominin relatives began controlling fire 1.5 million years ago. Until very recently, we’ve been limited in our ability to manage burn wounds wi...

9 Juni 55min

Special Episode: Alexandra Sifferlin & The Elusive Body

Special Episode: Alexandra Sifferlin & The Elusive Body

An accurate diagnosis can give us so much. It can give us a path forward. It can give us answers to long-standing questions. And it can give us much-needed hope. Yet many people around the world wait ...

2 Juni 51min

Ep 211 Motion Sickness: It comes in waves

Ep 211 Motion Sickness: It comes in waves

It comes on sneakily. You become aware of your stomach. You break out in a cold sweat. Your mouth fills with saliva. And before you know it, you’re leaning over the side of the boat (or out of the car...

26 Maj 1h 16min

Ep 210 Histoplasmosis: Bats, birds, and budding yeast

Ep 210 Histoplasmosis: Bats, birds, and budding yeast

Once thought to be a rare, always fatal disease, histoplasmosis is now recognized as one of the most prevalent fungal infections in North America. It infects hundreds of thousands of people every year...

19 Maj 1h 18min

Special Episode: Dr. Olivia Weisser & The Dreaded Pox

Special Episode: Dr. Olivia Weisser & The Dreaded Pox

In a time when smallpox, tuberculosis, measles, and typhus ran rampant through the streets of London, there was another disease that instilled even more fear than these other killers: syphilis. So fea...

12 Maj 51min

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