Special Episode: Human African Trypanosomiasis & Drug Development

Special Episode: Human African Trypanosomiasis & Drug Development

Our episode last week ended on a hopeful note, a rare occurrence for this podcast, and it was due in large part to the incredible decline in reported cases of human African trypanosomiasis (HAT) over the past decade. In this bonus episode, we explore one of the major reasons behind this drop in HAT: the new medication fexinidazole, developed through a partnership between the Drugs for Neglected Diseases initiative (DNDi), a non-profit organization dedicated to developing new treatments for neglected diseases and Sanofi, a French healthcare company. We are thrilled to be joined by two researchers from DNDi, Dr. Nathalie Strub-Wourgaft and Dr. Wilfried Mutombo Kalonji, who share their insights into the challenges associated with bringing a medication all the way from its development stage, to testing it in the field, and finally ensuring that access is provided for those who need it most. We also chat about how this treatment works, the impact that COVID-19 has had on screening efforts for sleeping sickness, the lessons learned from fexinidazole’s development, and so much more. Tune in wherever you get your podcasts! And when you’re finished with the ep, check out this beautiful video from DNDi chronicling the story of fexinidazole: A doctor’s dream: A pill for sleeping sickness.

See omnystudio.com/listener for privacy information.

Avsnitt(281)

From the Vault - Hepatitis B: Hepatiti, Take 2 (Ep 89)

From the Vault - Hepatitis B: Hepatiti, Take 2 (Ep 89)

This episode originally aired on January 25th, 2022. In light of the recent changes by RFK jr’s Advisory Committee on Immunization Practices (ACIP) to eliminate the universal birth dose of the hepatit...

23 Dec 20251h 30min

Ep 196 Health Myths: Fact or fiction?

Ep 196 Health Myths: Fact or fiction?

Did your grandma ever warn you against going out in the cold with wet hair because “you’ll catch your death”? Or have you ever tossed a few more carrots into your shopping basket in the hope that they...

16 Dec 20251h 6min

Special Episode: Dr. Homer Venters & Outbreak Behind Bars

Special Episode: Dr. Homer Venters & Outbreak Behind Bars

[Content warning: self-harm, suicide, violence] In this day and age, we are equipped with an abundance of tools and knowledge to fight the spread of disease. Yet what good does that toolkit do if we l...

9 Dec 202555min

Ep 195 Salt Part 2: The Substance

Ep 195 Salt Part 2: The Substance

We ended last week’s episode on a bit of a cliffhanger: is salt actually bad for us and if so, why does there still seem to be a debate? This week’s episode holds all the answers. We’re sifting throug...

2 Dec 202553min

Ep 194 Salt Part 1: The Seasoning

Ep 194 Salt Part 1: The Seasoning

Have you ever thrown a pinch of spilled salt over your left shoulder? Or said to someone “well, take his opinion with a grain of salt”? Or looked up the potential salary of a job listing? Salt is so d...

25 Nov 202555min

Special Episode: Gabriel Weston & Alive

Special Episode: Gabriel Weston & Alive

In an anatomy and physiology class, you may learn how the different heart valves work to circulate your blood, how the structure of your kidney helps to maintain electrolyte levels, and how the expans...

18 Nov 202549min

Ep 193 Necrotizing Fasciitis: A strange beast

Ep 193 Necrotizing Fasciitis: A strange beast

If you were asked to describe necrotizing fasciitis in three words, you might choose: rapid, deadly, and rare. The third of those adjectives may provide some comfort, but the first two are the clear i...

11 Nov 20251h 7min

Ep 192 New World Screwworm: Oh-oh here they come

Ep 192 New World Screwworm: Oh-oh here they come

It’s the stuff nightmares are made of. A fly lands on an open wound and lays hundreds of eggs, from which hatch countless ravenous maggots. There they writhe, devouring flesh, insatiable and relentles...

4 Nov 20251h 10min

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