Bedside Rounds1 Aug 2017

25 - Salt Water

Intravenous or IV fluids are a ubiquitous treatment in medicine, and one of the most cost-effective treatments that we have, costing less than a cup of coffee in the developing world. But it wasn't always this way. In this episode, called Salt Water, we go back to the second great cholera epidemic, where a young doctor developed IV fluids to help fight this mysterious disease, only to see his invention abandoned for over half a century. We also have a new #AdamAnswers about bloodletting. So join us for another rollicking adventure of Bedside Rounds, a tiny podcast about fascinating stories in clinical medicine!

Sources:

Foex B. How the cholera epidemic of 1831 resulted in a new
technique for fluid resuscitation. Emerg Med J 2003;20:316–318.
Gill G. William O'Shaughnessy and the forgotten cure for cholera
in the 1832 British epidemic.
Letter from Lord Cavendish: Online at: http://mssweb.nottingham.ac.uk/elearning/view-text.asp?resource=HealthHousing&ref=pwh287&theme=3&view=text&page=1
O'Shaughnessy, W.B. (1838–40). "Case of Tetanus, Cured by a Preparation of Hemp (the Cannabis indica.)". Transactions of the Medical and Physical Society of Bengal. 8: 462–469.
Chan C, et al. Historical Epidemiology of the Second Cholera Pandemic: Relevance to Present Day Disease Dynamics. PLOS One: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072498
BB4: Diary of an Epidemic. Online at: http://www.bbc.co.uk/radio4/history/longview/longview_20030415.shtml
Kresta R. The Origin of IV Fluids. Discover Magazine. Online at: http://blogs.discovermagazine.com/bodyhorrors/2016/05/31/intravenous-fluids-cholera/#.WX9z4JdtmUl
Prasad V and Cifu A, Medical Reversal: Why We Must Raise the Bar Before Adopting New Technologies. Yale J Biol Med. 2011 Dec; 84(4): 471–478.

Further reading:

r/AskHistorians thread: https://www.reddit.com/r/AskHistorians/comments/6nzbfz/if_bloodletting_was_rubbish_why_was_it_considered/
Ending Medical Reversal by Cifu and Prasad. On Amazon at: https://www.amazon.com/Ending-Medical-Reversal-Improving-Outcomes/dp/1421417723

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(86)

48 - Micrographia

Germs are regarded today with a combination of fear and disgust. But mankind's first introduction to the microbial world started off on a very different foot. In this episode, as part of a larger seri...

28 Aug 201939min

Summer Shorts #3 - Insulin Drama

Bedside Rounds is on a summer vacation! In the meantime, I'm joined by journalist Dan Weissmann of the podcast An Arm and a Leg to talk about the tawdry history of the discovery of insulin.

26 Juli 201922min

47 - The Criteria

Can we ever know what causes a chronic disease? In this episode, I'm joined again by Dr. Shoshana Herzig to finish a three-part miniseries on Bradford Hill and Doll's attempts to prove that smoking ca...

24 Juni 201944min

46 - Cause and Effect

Does smoking cause lung cancer? How could you ever know? The second in a three-part series on causality, I'm joined by Dr. Shoshana Herzig to discuss how Austin Bradford Hill and Richard Doll set out ...

20 Maj 201938min

45 - The French Disease at 500

In 1495, a mysterious and deadly plague struck the city of Naples. Over the next 500 years, the medical attempts to understand and treat this new disease -- syphilis -- would mold and shape medicine i...

22 Apr 20191h 9min

44 - The Great Smog

What was behind the mysterious increase in lung cancer deaths at the turn of the 20th century? The first of a three-parter investigating the cigarette-smoking link and causality, this episode looks at...

25 Mars 201942min

43 - The Cursed

What killed Charles II of Spain, the inbred monarch whose autopsy famously showed a heart the size of a peppercorn, a head full of water, and a bloodless body? This episode addresses that medical myst...

18 Feb 201943min

42 - The Lady with the Lamp

Florence Nightingale stands as one of the most important reformers of 19th century medicine -- a woman whose belief in the power of reason and statistical thinking would critically shape the both the ...

14 Jan 201939min