From Dopamine to Disease: Understanding the Addiction-Cancer Connection

From Dopamine to Disease: Understanding the Addiction-Cancer Connection

From Dopamine to Disease: Understanding the Addiction-Cancer Connection.

What’s the hidden link between addiction and cancer? In this Cracking Addiction episode, Dr. Ferghal Armstrong and UC San Diego’s Dr Raphael E. Cuomo reveal how lifestyle and cancer risk intertwine.

Discover how cancer prevention and healthy lifestyle choices can transform your health and lower risks, including skin cancer and lifestyle choices like sun exposure or smoking.

Dr. Cuomo debunks the myth that lifestyle and cancer are solely genetic, diving into how addiction and cancer connect through neurobiology—think dopamine, mesolimbic pathways, and epigenetics.

Learn how modifiable habits, from processed foods and red meat to screen time and stress, fuel lifestyle and cancer risk. Skin cancer and lifestyle choices, like neglecting sunscreen, and behavioural addictions, like binge-watching or social media scrolling, silently drive disease.

This episode empowers you with cancer prevention and healthy lifestyle strategies to break free from self-sabotaging cycles.

Dr. Armstrong and Dr. Cuomo unpack actionable health tips, showing how lifestyle and cancer are shaped by daily choices. From understanding addiction’s grip on your brain to adopting cancer prevention and healthy lifestyle habits, this science-backed guide offers hope for addiction recovery and long-term wellness.

Whether you’re aiming to reduce lifestyle and cancer risk or live healthier, this video delivers insights on the biology of wellness and proactive prevention.

Get The Book Crave: The Hidden Biology of Addiction and Cancerhttps://raphaelcuomo.com/crave

Subscribe for more addiction and cancer insights! Share your health journey below!

Chapters:00:00:00 Introducing Dr. Raphael Cuomo: Background and Professional Focus

00:01:59 Lifestyle Factors and Cancer Risk: Beyond Smoking

00:02:44 The Role of Diet, Sugar, and Red Meat in Cancer Development

00:04:42 Addictive Behaviors and Lesser-Known Cancer Risks

00:05:29 Moving Public Health “Upstream”: Changing Mindsets, Not Just Behaviours

00:06:29 Why We Struggle to Establish Healthy Habits00:07:52 Addiction Pathways: Dopamine and Lifestyle Diseases

00:08:08 Cancer as a Modifiable Lifestyle Disease

00:09:01 Brain Pathways Involved in Addiction

00:10:11 Dopamine: “Wanting” vs. Pleasure, and the Hijacking of Reward Systems

00:12:10 How Addictive Foods and Behaviours Fuel Chronic Illness

00:13:43 The Modern Difficulty with Rest, Repair, and Reflection

00:15:03 Linking Lifestyle Addiction to Cancer: The Prevention 2.0 Model

00:16:29 Are Addictive Substances Directly Carcinogenic

00:17:55 How Process Addictions like Food and Screen Time Affect Cancer Risk

00:20:10 Epigenetics and How Lifestyle Changes Influence Cancer Outcomes

00:22:39 The Chain: Addiction, Lifestyle, Epigenetics, and Cancer Risk

00:23:22 Professor Cuomo’s Book: The Hidden Biology of Addiction and Cancer

00:24:49 Closing Remarks and Reflections on Healthy Change

#AddictionAndCancer #CancerPreventionAndHealthyLifestyle #LifestyleAndCancerRisk #SkinCancerAndLifestyleChoices

Avsnitt(218)

Benzodiazepines

Benzodiazepines

In episode 58 of Cracking Addiction we discuss the pharmacology of benzodiazepines and their interaction with the GABA-A receptor, the different types of benzodiazepines and their different half lives and effects, discuss how to calculator benzodiazepine dose equivalence, the increased risks of benzodiazepine overdose when compared with other medications especially with opioid medications and the pharmacokinetics and metabolism of benzodiazepines.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

21 Sep 202221min

Lifestyle Medicine in Addiction

Lifestyle Medicine in Addiction

In today's episode of Cracking Addiction we are joined by Dr Sam Manger the President of the Australasian Society of Lifestyle Medicine and host of the GP Show podcast who discusses lifestyle interventions in substance use disorders. Lifestyle interventions can be safe and efficacious interventions and there is a growing evidence base for certain lifestyle interventions in some substance use disorders. For further information on lifestyle interventions in substance use disorders please read our journal article on this topic at: https://www1.racgp.org.au/ajgp/2022/august/lifestyle-interventions-for-substance-use-disorderThe GP Show podcast and other lifestyle medicine resources: https://thegpshow.comDiscussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

14 Sep 202228min

Methamphetamine relapse prevention

Methamphetamine relapse prevention

In this episode of Cracking Addiction we discuss relapse prevention strategies with regards to methamphetamine use and discuss harm reduction strategies, how to avoid a lapse becoming a relapse, the Matrix Model, motivational intervention and contingency management. We also discuss the importance of peer support programs in aiding people on their path to recovery from substance use disorder and discuss the evidence surrounding pharmacotherapy interventions for methamphetamine use disorder.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

7 Sep 202217min

Methamphetamine withdrawal

Methamphetamine withdrawal

In this Episode of Cracking Addiction we discuss the three phases of methamphetamine withdrawal, strategies to manage the methamphetamine withdrawal including possible medication options and the ongoing psychosocial support required to support patients during methamphetamine withdrawal. Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle. Latest Blogs https://www.meducate.com.au/blogs About Meducate ® Meducate provides online education for doctors, clinicians, health professionals and the public. See the website to browse the many different talks and courses available https://www.meducate.com.au

31 Aug 202217min

Methamphetamine and amphetamines

Methamphetamine and amphetamines

In this episode of Cracking Addiction we mainly speak about methamphetamines but also amphetamines and discuss the amphetamine class of drugs and their physiological effects, the different types of methamphetamines, symptoms of intoxication with amphetamines, side effects of methamphetamine and amphetamines including the various organ systems they impact and in particular the potential psychological and psychiatric harms and focus on drug induced psychosis. Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

24 Aug 202223min

Living with Addiction

Living with Addiction

In this episode of Cracking Addiction we are privileged to have Steven McDonald who discusses his lived experience with addiction and his path towards recovery. Steven speaks openly and honestly about his past history and his experiences. Steven has written a book 'Thanks for Letting Me Share' which is a book of 368 quotes that have helped him along his journey. The book is available on Amazon https://www.amazon.com/dp/B09BCG67JK/ and Facebook https://www.facebook.com/Thanks-for-Letting-Me-Share-book-102078078856382Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

16 Aug 202236min

Cannabis hyperemesis syndrome

Cannabis hyperemesis syndrome

In this episode of Cracking Addiction we discuss cannabis hyperemesis syndrome, the various theories surrounding the pathophysiology of cannabis hyperemesis, treatment of cannabis hyperemesis syndrome, diagnostic criteria for cannabis hyperemesis syndrome and discuss the other potential differential diagnoses of cyclic vomiting symptoms and how cannabis hyperemesis syndrome is often a diagnosis of exclusion.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

10 Aug 202216min

Synthetic cannabis

Synthetic cannabis

In this episode of Cracking Addiction we discuss the variety within the class of synthetic cannabinoids, symptoms of synthetic cannabis intoxications, side effects and complication of synthetic cannabis usage and specific considerations in withdrawal management.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

3 Aug 202214min

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