#118 - Do Indolent Systemic Mastocytosis Patients & Providers Agree on Symptom Control?

Do patients and their healthcare teams view the impact of indolent systemic mastocytosis on quality of life in the same way?

In this episode of The Itch Review, we unpack key findings from a May 4, 2025, descriptive study from The Journal of the Advanced Practitioner in Oncology, “Patient and Advanced Practitioner Perspectives on Symptom Burden and Symptom Management in Indolent Systemic Mastocytosis.”

Is there a disconnect between what patients feel and what providers think when it comes to indolent systemic mastocytosis (ISM)? A new study suggests yes, revealing a mismatch between how patients and advanced practitioners (APs) perceive disease control and what that means for care. This episode dives into whether research like this could help bridge the gap between patient experience and clinical perspective.

What we cover in our episode about the indolent systemic mastocytosis:

• Understanding ISM: What makes indolent systemic mastocytosis a unique multisystem condition?
• Symptom burden explained: Frequency, severity, duration, distress, and functional interference.
• Patient vs practitioner views: Understanding the most impactful symptoms differs from patient to AP.
• Practical tools: The Indolent Systemic Mastocytosis-Symptom Assessment Form (ISM-SAF) is a validated instrument that can be used to determine symptoms and severity.
• Barriers and solutions: Why tracking symptoms is hard and how clinics can improve coordination.
• AP-focused Toolkit: Resources to help nurse practitioners, PAs, and pharmacists provide patient-centered ISM care.

GET THE INFOGRAPHIC HERE

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The Itch Review, hosted by Dr. Gupta, Kortney, and Dr. Blaiss, explores the latest allergy and immunology studies, breaking down complex research in conversations accessible to clinicians, patients, and caregivers. Each episode provides key insights from journal articles and includes a one-page infographic in the show notes for easy reference.

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This podcast is made in partnership with The Allergy & Asthma Network.

Thanks to Blueprint Medicines for sponsoring today’s episode.

This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.