Moderna and Flagship Pioneering: Noubar Afeyan

Moderna and Flagship Pioneering: Noubar Afeyan

In the field of bio-tech, it can take 10 years and millions of dollars to see if an experimental idea might turn into a life-saving treatment—if it ever does. Noubar Afeyan fully understood those risks when he co-founded Moderna in 2010. He and his colleagues were looking for a way to deploy the messenger RNA molecule to tackle life-threatening diseases. In January of 2020, an urgent opportunity presented itself in the form of a deadly virus that was spreading across the globe. At a breathtaking pace, Moderna produced a prototype for a COVID-19 vaccine, partnered with the NIH to test it, and produced millions of doses, becoming part of the most rapid vaccine roll-out in human history. While Moderna is the best known of Noubar's companies, he has launched many others in the bio-tech space as part of Flagship Pioneering, his multi-billion dollar venture studio. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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The Lip Bar: Melissa Butler

The Lip Bar: Melissa Butler

While working long hours as a Wall Street analyst, Melissa Butler started making lipstick in her kitchen as a hobby. But it soon turned into an obsession, costing thousands of dollars. She was frustrated by the lack of diversity in the cosmetics industry, and as a Black woman, wanted to create lipstick colors that complimented her complexion and style. So in 2010, she launched The Lip Bar, with bold colors like green and purple, and boozy names like "Cosmo" and "Sour Apple Martini." Undeterred by a disastrous appearance on Shark Tank with her partner Rosco Spears, Melissa was motivated to pitch her lipstick to Target, and in 2016, launched a new color on Target's online store. Today, The Lip Bar has expanded to 500 Target stores, and has continued to grow a following, despite the pain points of the pandemic. Order the How I Built This book at: https://smarturl.it/HowIBuiltThisSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Nov 20201h 20min

How I Built Resilience: Father Gregory Boyle of Homeboy Industries

How I Built Resilience: Father Gregory Boyle of Homeboy Industries

Father Gregory Boyle is the founder of Homeboy Industries, one of the largest gang-intervention, rehabilitation and re-entry programs in the world. He speaks with Guy about how the Los Angeles based organization has adapted to continue training and employing people during the pandemic. These conversations are excerpts from our How I Built Resilience series, where Guy talks online with founders and entrepreneurs about how they're navigating turbulent times.Order the How I Built This book at:https://smarturl.it/HowIBuiltThisSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

19 Nov 202025min

Kenneth Cole: Kenneth Cole

Kenneth Cole: Kenneth Cole

Kenneth Cole launched his shoe business out of a forty-foot truck in midtown Manhattan and quickly became known as an up-and-coming designer with an eye for street fashion. In 1986, he made a bold move by associating his nascent brand with a controversial issue at the time: the AIDS crisis, and the vital need for research. Through the 1990s and 2000s, Kenneth grew the company into a $500M brand, leading it through downturns, department store consolidation, an IPO and a return to private ownership. Throughout, he stayed committed to AIDS research and many other social causes. Order the How I Built This book at: https://smarturl.it/HowIBuiltThisSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Nov 20201h 15min

Dropbox: Drew Houston

Dropbox: Drew Houston

In 2006, Drew Houston got on a bus from Boston heading to New York. He planned to use the three-hour ride to get some work done, so he opened his laptop, and realized he had left his thumb drive with all of his work files at home. Drew decided he never wanted to have that problem again. On that bus ride, he started writing the code to build a cloud-based file storage and sharing service he called Dropbox. Fourteen years later, Drew and his co-founder, Arash Ferdowsi, have built Dropbox into a public company worth close to $8 billion. Order the How I Built This book at: https://smarturl.it/HowIBuiltThisSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Nov 202047min

How I Built Resilience: Varshini Prakash of Sunrise Movement

How I Built Resilience: Varshini Prakash of Sunrise Movement

Guy talks with Varshini Prakash, co-founder of Sunrise Movement, a grassroots organization that's fighting to make climate change a top priority in the US. The group launched in 2017 and has since grown into one of the largest youth movements in the country. These conversations are excerpts from our How I Built Resilience series, where Guy talks online with founders about how they're navigating these turbulent times.Order the How I Built This book at:https://smarturl.it/HowIBuiltThisSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Nov 202023min

Famous Dave's: Dave Anderson

Famous Dave's: Dave Anderson

Growing up in 1960's Chicago, Dave Anderson didn't eat much deep dish. Instead, his dad took the family to the South Side for barbecue, and those memories—and aromas—stayed with him. For years, Dave tinkered with his own recipes for sauces and sides while working as a salesman and business advisor to Native American tribes. Finally in 1994, he opened his first barbecue shack in the last place you might expect to find one: the little town of Hayward, Wisconsin. The chain grew quickly—too quickly—and Dave developed a love-hate relationship with the brand he'd created, but never lost his passion for smoked ribs and brisket. Today, Famous Dave's has around 125 restaurants across the U.S., making it one of the largest barbecue chains in the country. Order the How I Built This book at: https://smarturl.it/HowIBuiltThisSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Nov 20201h 15min

How I Built Resilience: Justin Gold of Justin's

How I Built Resilience: Justin Gold of Justin's

Justin Gold is the founder of Justin's, known for its nut butters and chocolate peanut butter cups. He talks about how he started by pulverizing peanuts in his home blender, and describes how his customers are shopping differently during the pandemic. These conversations are excerpts from our How I Built Resilience series, where Guy talks online with founders and entrepreneurs about how they're navigating these turbulent times.Order the How I Built This book at:https://smarturl.it/HowIBuiltThisSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

31 Okt 202021min

How I Built Resilience: Cheryl Contee of Do Big Things

How I Built Resilience: Cheryl Contee of Do Big Things

Do Big Things is a Black woman-led, mission-driven digital agency that works with companies like Google, Etsy, and the NAACP, and has a staff that's 50% people of color. The agency's CEO and founder Cheryl Contee says having a diverse team is a strategy for authentic engagement. These conversations are excerpts from our How I Built Resilience series, where Guy talks online with founders and entrepreneurs about how they're navigating turbulent times. Order the How I Built This book at:https://smarturl.it/HowIBuiltThisSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Okt 202019min

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