The Fastest-Acting Nootropic I’ve Ever Used  : 1303

The Fastest-Acting Nootropic I’ve Ever Used : 1303

What if one spray could upgrade your brain, protect your mitochondria, and outperform IV therapy and liposomal supplements? In this episode, you’ll discover the breakthrough science behind topical glutathione delivery that uses your skin’s water channels to raise intracellular glutathione levels in just 60 seconds. Learn how this powerful antioxidant works at the cellular level to reduce oxidative stress, support mitochondrial function, and drive real improvements in brain health, emotional resilience, and human performance.


Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR


Host Dave Asprey sits down with Nayan Patel, a world-leading pharmacist and formulator who pioneered this next-gen delivery method. With over two decades of clinical work in functional medicine, Nayan has helped reshape how we think about glutathione benefits, systemic detox, and performance optimization. His research shows that topical delivery bypasses traditional fat-based absorption, achieving higher brain uptake and faster results than IVs or capsules.


You’ll learn:

• Why glutathione for longevity is foundational to biohacking

• How it protects against cellular inflammation and improves TBI recovery issues

• Why pairing glutathione with NAD+, vitamin C, or pharmaceutical nicotine creates a powerful synergy

• How it preserves NAD+, supports sirtuins, and enhances ATP production

• When to use glutathione as an immune booster for resilience and recovery


This conversation also reveals the truth behind liposomal supplements, how your age affects glutathione absorption, and why this molecule is critical for anyone using nootropics, in ketosis, or pushing metabolic limits.


This episode is essential listening for anyone into biohacking, cold therapy, functional medicine, or RFK-style medical freedom. You’ll walk away with practical tools to boost nitric oxide naturally, prevent dysfunction, and optimize your biology whether you’re on a carnivore diet or just looking for an edge.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.


Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.


Resources:

• Auro Wellness Website: Use code ‘dave10’ at checkout https://aurowellness.com/

• Dave Asprey’s Website: https://daveasprey.com

• Danger Coffee: https://dangercoffee.com/DAVE15

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

00:00 Trailer

00:20 Intro

01:12 Water Channel Delivery Explained

02:25 What Makes Glutathione Special

05:04 Why IVs and Liposomes Fail

06:29 Measuring Glutathione in the Brain

10:42 Key Benefits and Use Cases

20:49 Emotional Resilience Effects

23:54 Sensitivity and Response

24:55 Best Timing for Use

25:53 Workout Performance Boost

26:47 Brain Health and TBI Support

28:22 Best Stack Combinations

29:32 Nicotine + Glutathione Synergy

33:18 Longevity, Sirtuins, and Genes

40:36 Glutathione as Immune Booster

43:15 Peptides and Next-Gen Hacks

45:29 Dosing Tips and Wrap-Up

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Avsnitt(1381)

#38: Mark Divine, Bulletproof Warrior and SEALFIT's founder

#38: Mark Divine, Bulletproof Warrior and SEALFIT's founder

Mark Divine is from upstate New York and did his formal undergraduate education at Colgate University. His years at Colgate University were focused on the athletic endeavors of competitive swimming, rowing and triathlon racing. Mark pursued a Ph.D. in Leadership at the University of San Diego and served as an Adjunct Professor of Leadership in their undergraduate school. The Doctorate was interrupted by a one-year recall to active duty for Operation Iraqi Freedom. The recall took him to Baghdad in 2004 with SEAL Team One to conduct a special project studying the future role of the USMC in the Special Operations Command. Upon his return home he left USD to focus on developing SEALFIT and put his Unbeatable Mind training philosophy to work on a new generation of Special Ops candidates. You will learn all about this amazing program and more in this exclusive interview! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

8 Mars 201355min

Bulletproof Exec 37 w The Caltons.mp3

Bulletproof Exec 37 w The Caltons.mp3

The Caltons are among the world's leading experts on the topics of weight management, lifestyle medicine and micronutrient deficiency. Their high success rate working with adults and children to achieve sustainable weight loss and reverse health and disease conditions has made their consultancy highly sought after by celebrities, athletes and top corporate executives around the world. It is their belief that becoming micronutrient sufficient is the first step towards preventing and reversing many of today's most prevalent health conditions and diseases. In today's podcast, they discuss their new book, Rich Food, Poor Food, and go into a step-by-step guide of how to shop for food, make good choices, and discuss top micro-nutrient deficiencies.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Feb 201348min

Podcast #36:Hacking your Biome with uBiome's Jessica Richman

Podcast #36:Hacking your Biome with uBiome's Jessica Richman

Jessica Richman started and sold her first company after high school. Returning to formal education, she attended Stanford University, where she earned degrees in Economics and Science, Technology & Society (emphasis in computer science). Along the way, she worked for Google, McKinsey, Lehman Brothers, the Grameen Bank, and top-tier Silicon Valley venture firms. Currently a doctoral student at Oxford University, her academic interests include social networks, innovation, collective intelligence, and entrepreneurship. uBiome is the world’s first effort to map the human microbiome with citizen science. While the sequencing of the human genome has provided invaluable knowledge, it is very difficult to change our own genetic makeup. The microbiome, in contrast, is much more easily changed through simple means such as healthful probiotic cultures and other lifestyle interventions. The microbiome thus may provide some of the most important medical breakthroughs of our era. uBiome will ultimately empower participants to manage their microbiomes to improve their health as well as make important scientific discoveries for humanity. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Jan 201331min

Podcast #35: Bulletproof Your Nervous System with Jay Schroeder

Podcast #35: Bulletproof Your Nervous System with Jay Schroeder

World-class strength and neurological conditioning authority, and creator of new technology that stimulates rapid nervous system and cellular improvements He has studied the greatest training systems of the world, not to find the successes but to establish the point at which they failed. He then put together his system of training to overcome these points of failure. He has traveled to Eastern bloc countries and developed working relationships with some of the most knowledgeable in the field. He has designed unique protocols for use with his device as well as the typical equipment in the gym setting, as they relate to rehab strength, injury prevention and elite athletic mastery. Elite level pro athletes pay more than $50,000 to train with Jay. He has designed unique protocols for use with the ARP as well as the typical equipment in the gym setting, as they relate to rehab strength, injury prevention and elite athletic mastery. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Jan 201351min

Podcast #34: The Perfect Health Diet with Paul Jaminet

Podcast #34: The Perfect Health Diet with Paul Jaminet

Paul Jaminet. Ph.D. was an astrophysicist at the Harvard-Smithsonian Center for Astrophysics, became a software entrepreneur during the Internet boom, and now provides strategic advice to entrepreneurial companies while pursuing research in economics. Paul’s experience overcoming a chronic illness has been key to his views of aging and disease, and in writing his new book Perfect Diet Solution. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Dec 201240min

Podcast #33: Injury prevention and Wellness with Dr. Justin Marchegiani

Podcast #33: Injury prevention and Wellness with Dr. Justin Marchegiani

Dr. Justin Marchegiani is a graduate of the University of Massachusetts at Amherst with a B.S. degree in Kinesiology and Pre-medical studies. Dr. Justin has completed his Doctorate degree in Chiropractic Medicine from Life West University. Dr. Justin has completed post graduate study in the area of clinical nutrition, exercise and functional medicine so he can offer the most cutting edge techniques to help address his patient’s growing health care needs. Justin is head of Just In Health Wellness Clinic, a leading systems and functional medical provider who treats patients and athletes using biohacking and quantification. He can help you Bulletproof your game through education on injury prevention and performance enhancement! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Dec 201236min

Podcast #32: Hacking your Heart and Preventing Diabetes with Dr. Rocky Patel

Podcast #32: Hacking your Heart and Preventing Diabetes with Dr. Rocky Patel

Dr. Patel is a Bulletproof Physician.  He is a family physician whose practice is focused on the prevention, early detection and treatment of Diabetes and Heart Attack.  He knows his stuff, he lost over 85 lbs practicing what he preaches. He uses Bulletproof diet principles in treating patients in his practice at risk for or who have developed diabetes and/or cardiovascular disease.   In addition, he is the chief medical officer for Heart Fit for Duty, providing similar services to the first responder community.  For those of you interested in WellnessFx in Arizona, he is a WellnessFX practitioner and his family medical practice is based in Gilbert, Arizona.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Nov 20121h 15min

Podcast #31: Hack Your Sleep with Dr. Jonathan Wisor, Ph.D.

Podcast #31: Hack Your Sleep with Dr. Jonathan Wisor, Ph.D.

Dr. Wisor is one of the foremost researchers on sleep and nervous system function.  His laboratory is funded by both the Department of Defense and the National Institute of Neurological Disorders and Stroke to apply molecular genetic and biochemical techniques to study sleep. Dr. Wisor comes on the show today to talk about how you can use biochemistry and the latest research to improve sleep and your quality of life. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Sep 20121h 16min

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