Dr Karan Explores25 Juli 2025

Ozempic Is Just the Beginning: What’s Next in Weight Loss Drugs | Dr Spencer Nadolsky

💬 Dr Spencer Nadolsky is an obesity and lipid specialist, and an expert in GLP-1 care. He’s also the co-host of the Docs Who Lift podcast.

⚡️In this episode Spencer and I discuss emerging research around weight loss injections tirzepatide and semaglutide, known as Ozempic, Wegovy and Mounjaro - and discuss the proper use of these drugs.

🎧 Stay tuned to find out:

➡︎ Why old restrictions on weight loss drugs are no longer being enforced

➡ How a combo of GLP-1 and GIP may be even more revolutionary for weight loss

➡︎ Why most people have to take these drugs for life

➡︎ Why people get so angry when people lose weight on GLP-1s

➡︎ How GLP-1 drugs are going to make weight-loss surgery extinct

📕 Chapters

(0:41) The non-weight loss benefits from GLP-1 use

(4:55) Getting the dosage right

(7:24) Drugs of the future

(11:09) How to get started on a weight-loss injection

(16:38) Why restrictions on weight loss drugs are being lifted

(19:46) Why people get mad about GLP-1 use

(23:57) Do you have to take these drugs for life?

(27:55) Do fat cells have memory?

(29:25) What if you want to stop GLP-1 use?

(31:48) The mental health drawbacks of weight loss drugs

(35:44) Unique insights from Spencer’s time with patients

(38:47) Is excessive muscle loss really a big problem?

(42:46) Should everyone be taking GLP-1s?

(45:14) Will weight loss surgeries go extinct?

(49:11) GLP supplements are a scam

📱 Connect with me:

TikTok: https://www.instagram.com/drkaranrajan

YouTube: https://www.youtube.com/@DrKaran

Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Spencer:

Instagram: https://www.instagram.com/drnadolsky/

X: https://x.com/DrNadolsky

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

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