Ep. 15 - AI Factories, Wicked Problems, and the Limits of Alignment

In this episode of In The Long Run, we discuss Anthropic’s growing role in AI, from its collaboration with the Vatican on ethical questions to its compute deal with xAI. We also explore Andrej Karpath...

30 Maj 41min

Agentic AI is moving from clever chat to real work. In this episode, Jim and João discuss GPT Image 2.0, Codex, GPT-5.5, agents in ChatGPT, and why these tools matter beyond software development. They...

2 Maj 38min

This week's episode opens with the Artemis II launch as a jumping-off point: progress doesn't happen automatically, it takes investment and will. Jim and João then unpack Alberto Romero's "How to Surv...

2 Apr 40min

Brain cells on a chip learning to play Doom: early signs of biological computing as an alternative to silicon chipsEmbodied intelligence through a simulated fly: testing whether cognition needs a body...

21 Mars 48min

In this episode of "In the long run", we unpack the escalating clash between the U.S. “Department of War” (Pentagon) and Anthropic, centered on whether a private AI company can restrict government use...

6 Mars 45min

Something Big is Happening… and we can feel it in the AI tools, the timelines, the culture and our business.In this episode of In the Long Run, we unpack Matt Schumer’s viral article and ask what’s si...

20 Feb 43min

In this episode we debate whether it makes sense to wait for the future, try to lead the frontier, or invest in the present — and what that means for change-management in an AI world.We also cover: th...

26 Nov 20251h 2min

This week’s episode: Jim attended an event with OpenAI in London and shares some highlights. OpenAI’s reorganisation has been finalised, sparking fresh discussions about AGI timelines. There was also ...

13 Nov 202546min