
TWiV 860: Evading a Toll on the road to RNA vaccines
TWiV reviews a seminal paper showing that chemically modified bases in RNAs suppress recognition by Toll-like receptors, a finding that that was essential for the development of COVID-19 mRNA vaccines...
30 Jan 20221h 48min

TWiV 859: COVID-19 clinical update #99 with Dr. Daniel Griffin
In COVID-19 clinical update #99, Daniel Griffin discusses Omicron disease severity, neurologic manifestations in children, testing outcomes during multiple infections, boosters improve VE and VD, boos...
29 Jan 202237min

TWiV 858: The vax of life with John Mascola
John Mascola joins TWiV to discuss the history and mission of the NIH Vaccine Research Center, how it prepared for devising pandemic vaccines, and development of the COVID-19 vaccines. Hosts: Vincent ...
28 Jan 20221h 48min

TWiV 857: Not just antibody, Jon Yewdell
Jon Yewdell returns to TWiV to discuss how antibodies are made, vaccination against SARS-CoV-2, antigenic variation of the virus, booster shots, and more. Hosts: Vincent Racaniello, Dickson Despommier...
23 Jan 20221h 39min

TWiV 856: COVID-19 clinical update #98 with Dr. Daniel Griffin
In COVID-19 clinical update #98, Daniel Griffin reviews COVID-19 in South Africa, recognition of Omicron by ancestral T cells, booster effectiveness against disease, infection and vaccination in pregn...
22 Jan 202251min

TWiV 855: T time with Alessandro Sette
Alessandro Sette returns to TWiV to discuss the observation that SARS-CoV-2 vaccination induces T cells that are able to cross-recognize variants Alpha to Omicron. Hosts: Vincent Racaniello, Rich Cond...
21 Jan 20221h 36min

TWiV 854: Omicron is evasive
TWiV reviews findings that increased fitness of the Omicron variant is due to immune evasion, not an increase in intrinsic transmissibility, and determination of infectious viral load in patients infe...
16 Jan 20222h 5min

TWiV 853: COVID-19 clinical update #97 with Dr. Daniel Griffin
In COVID-19 clinical update #97, Daniel Griffin covers immunity after infection recognized by CDC, outcomes before and after Omicron, infectious viral load in Delta vs Omicron, PCR vs rapid antigen te...
15 Jan 202253min




















