Ep 339 - ECA Stack & Yohimbine

Ep 339 - ECA Stack & Yohimbine

In this episode of Iron Culture, Helms and Trex have a lengthy discussion about the ECA stack and yohimbine. The history, the mechanisms, the regulatory changes, the practical applications – you name it, they cover it. Don’t miss this episode if you have an interest in fat loss, stimulants, or dietary supplementation in general.


Also, be sure to check out the newest issue of the MASS Research Review! Learn more at massresearchreview.com


Time stamps

0:00 Intro

4:18 New issue of the MASS Research Review

10:42 Helms contest prep update

13:15 The history of the ECA stack and supplement regulation

30:07 Ephedra vs Ephedrine

35:31 Why people took ephedrine / ECA stack

36:30 Trends in PED use over time

45:00 Research on the ECA stack

50:58 Banning lifters for stimulant use

53:15 Effects of ephedrine + caffeine on metabolism and fat loss

1:02:44 What does aspirin really add to the ECA stack?

1:13:00 Do NSAIDs blunt hypertrophy?

1:21:25 How yohimbine works (and yohimbe vs yohimbine distinction)

1:31:10 Regulatory status of yohimbine

1:32:58 Practical applications

Avsnitt(133)

Ep 340 - Protein: Valuable, But Overvalued

Ep 340 - Protein: Valuable, But Overvalued

In this episode, Drs Trexler and Helms discuss various topics including updates on Eric's surgery, the valuable (but very modest) effects of protein intake on muscle gains, incontinence after contest ...

13 Aug 20251h 21min

Ep 338 – The many eras of evidence-based fitness (ft. Dr. Jim Stoppani)

Ep 338 – The many eras of evidence-based fitness (ft. Dr. Jim Stoppani)

Back when Trex was a 14 year old, his wrestling coach noticed his passion for training and nutrition. This coach took Trex under his wing, and they started absorbing and applying as much information a...

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Ep 337 - Is There A Crisis In Exercise Science?

Ep 337 - Is There A Crisis In Exercise Science?

Join hosts Eric Trexler and Eric Helms as they explore the potential "replication crisis" in exercise science, drawing parallels to the well-documented crisis in psychology. In this episode, they delv...

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Ep 336 - The Science Of Being Cool & Attractive

Ep 336 - The Science Of Being Cool & Attractive

In this episode of Iron Culture, Dr. Eric Trexler and Dr. Lauren Colenso-Semple discuss science related to attractiveness, coolness, and personality type. They explore scientific studies on the factor...

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Ep 335: Sticking Points, Exercise Selection, and Long Muscle Length Training (ft. Dr. Stian Larsen)

Ep 335: Sticking Points, Exercise Selection, and Long Muscle Length Training (ft. Dr. Stian Larsen)

In this episode of Iron Culture, Eric Helms interviews Dr. Stian Larsen, who shares his journey from powerlifting to becoming a researcher in exercise science. They discuss the intricacies of biomecha...

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Ep 334 - Microplastics: Setting the Record Straight

Ep 334 - Microplastics: Setting the Record Straight

In this episode of Iron Culture, the Erics provide some updates, corrections, and clarifications related to their recent episode exploring the science of microplastics. After that they take a brief mo...

2 Juli 20251h 29min

Ep 333 - Are High-Protein Diets Really Harmless?

Ep 333 - Are High-Protein Diets Really Harmless?

In this episode of Iron Culture, Dr. Eric Helms talks about his forthcoming article in the MASS Research Review covering the purported harms of high-protein diets. This isn’t your typical oversimplifi...

25 Juni 20251h 34min

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