019 - DPD Deficiency: To Screen or Not To Screen?

019 - DPD Deficiency: To Screen or Not To Screen?

Questions? Comments? Send us a message! This academic article explores the complexities surrounding dihydropyrimidine dehydrogenase (DPD) deficiency screening in patients receiving 5-fluorouracil (5-FU) based chemotherapy. The authors present a case study of a fatal reaction to capecitabine, a prodrug of 5-FU, to illustrate the severe, potentially life-threatening toxicity that can occur in DPD-deficient individuals. The text analyzes various methods of DPD testing, highlighting their limita...

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Avsnitt(30)

024 - NEW FRONTIERS: Inhaled DMT for Treatment Resistant Depression

024 - NEW FRONTIERS: Inhaled DMT for Treatment Resistant Depression

Questions? Comments? Send us a message! This scientific article examines how inhaled DMT, paired with psychological support, impacts the overall well-being of healthy volunteers and individuals with ...

27 Juli 21min

023 - GLP-1 Agonists and Addiction:  Surprise!

023 - GLP-1 Agonists and Addiction: Surprise!

Questions? Comments? Send us a message! Recent research indicates that GLP-1 receptor agonists, originally developed for diabetes and obesity, show significant potential in treating substance use dis...

18 Mars 23min

022 - A 10 Minute Treatment for Depression : DMT in a Phase 2a Study

022 - A 10 Minute Treatment for Depression : DMT in a Phase 2a Study

Questions? Comments? Send us a message! We discuss a Phase 2a clinical trial investigating the use of intravenous DMT (SPL026) as a fast-acting treatment for major depressive disorder. The research d...

3 Mars 22min

021 - Ethics Roundtable: Prescribing Controlled Substances in a Terminally Ill Patient With Suspected Substance Abuse Disorder and Opioid Agreement Violations

021 - Ethics Roundtable: Prescribing Controlled Substances in a Terminally Ill Patient With Suspected Substance Abuse Disorder and Opioid Agreement Violations

Questions? Comments? Send us a message! This is an interdisciplinary ethics roundtable centered on a terminal lung cancer patient suspected of diverting methadone and violating his controlled substan...

27 Jan 17min

ACHPN Board Exam Review Part 6: Leadership

ACHPN Board Exam Review Part 6: Leadership

Questions? Comments? Send us a message! The ACHPN Prep (Advanced Certified Hospice and Palliative Nurse) series on the Topics in Palliative Medicine podcast consists of several parts designed to help...

12 Aug 202535min

020 - The Surrogate vs the Advance Care Plan

020 - The Surrogate vs the Advance Care Plan

Questions? Comments? Send us a message! This episode presents an "Ethics Roundtable" discussion, focusing on the complex case of a 68-year-old female veteran, LK, whose advanced directive conflicts w...

8 Aug 202517min

ACHPN Board Exam Review Part 5: Ethics and the Law

ACHPN Board Exam Review Part 5: Ethics and the Law

Questions? Comments? Send us a message! The ACHPN Prep (Advanced Certified Hospice and Palliative Nurse) series on the Topics in Palliative Medicine podcast consists of several parts designed to help...

5 Aug 202533min

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